Gremlin is the BMP antagonist required for maintenance of Shh and Fgf signals during limb patterning
about
The BMP antagonist follistatin-like 1 is required for skeletal and lung organogenesisGenetic analysis of the roles of BMP2, BMP4, and BMP7 in limb patterning and skeletogenesisThe bone morphogenetic protein antagonist gremlin 1 is overexpressed in human cancers and interacts with YWHAH proteinSMOC1 is essential for ocular and limb development in humans and miceDNA methylation-associated inactivation of TGFbeta-related genes DRM/Gremlin, RUNX3, and HPP1 in human cancersRegulation of the ovarian reserve by members of the transforming growth factor beta familyThe DAN family: modulators of TGF-β signaling and beyondGremlin 1 identifies a skeletal stem cell with bone, cartilage, and reticular stromal potential.Shh and Gli3 regulate formation of the telencephalic-diencephalic junction and suppress an isthmus-like signaling source in the forebrainFollistatin-like 1 in vertebrate developmentLaminin-511 is an epithelial message promoting dermal papilla development and function during early hair morphogenesisMammalian formin-1 participates in adherens junctions and polymerization of linear actin cablesSall genes regulate region-specific morphogenesis in the mouse limb by modulating Hox activitiesGenetic evidence that SOST inhibits WNT signaling in the limbMouse limb deformity mutations disrupt a global control region within the large regulatory landscape required for Gremlin expressionNoggin is required for normal lobe patterning and ductal budding in the mouse prostateMsx1 and Msx2 in limb mesenchyme modulate digit number and identityReciprocal epithelial-mesenchymal FGF signaling is required for cecal developmentHolocephalan embryos provide evidence for gill arch appendage reduction and opercular evolution in cartilaginous fishes.Vertebrate limb development: moving from classical morphogen gradients to an integrated 4-dimensional patterning systemPerspectives on hyperphalangy: patterns and processesA new molecular logic for BMP-mediated dorsoventral patterning in the leech HelobdellaIdiopathic pulmonary fibrosis: aberrant recapitulation of developmental programs?Fgfr1 signalling in the development of a sexually selected trait in vertebrates, the sword of swordtail fish.The origin of bmp16, a novel Bmp2/4 relative, retained in teleost fish genomesIdentification of genes associated with regenerative success of Xenopus laevis hindlimbs.Negative Smad expression and regulation in the developing chick limb.Prognostic significance of Gremlin1 (GREM1) promoter CpG island hypermethylation in clear cell renal cell carcinoma.Timed deletion of Twist1 in the limb bud reveals age-specific impacts on autopod and zeugopod patterningFormins in development: orchestrating body plan origami.Shh pathway activation is present and required within the vertebrate limb bud apical ectodermal ridge for normal autopod patterningEvolution of vertebrate appendicular structures: Insight from genetic and palaeontological data.A GREM1 gene variant associates with diabetic nephropathy.Gremlin1 plays a key role in kidney development and renal fibrosisGenomic deletion of a long-range bone enhancer misregulates sclerostin in Van Buchem disease.Genomic identification of regulatory elements by evolutionary sequence comparison and functional analysisTbx2 terminates shh/fgf signaling in the developing mouse limb bud by direct repression of gremlin1.Gremlin in the pathogenesis of hepatocellular carcinoma complicating chronic hepatitis C: an immunohistochemical and PCR study of human liver biopsies.Conserved cis-regulatory regions in a large genomic landscape control SHH and BMP-regulated Gremlin1 expression in mouse limb buds.Cooperative activity of noggin and gremlin 1 in axial skeleton development.
P2860
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P2860
Gremlin is the BMP antagonist required for maintenance of Shh and Fgf signals during limb patterning
description
2003 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
articolo scientifico
@it
artículu científicu espublizáu en 2003
@ast
im Juli 2003 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2003/07/01)
@sk
vědecký článek publikovaný v roce 2003
@cs
wetenschappelijk artikel (gepubliceerd op 2003/07/01)
@nl
наукова стаття, опублікована в липні 2003
@uk
name
Gremlin is the BMP antagonist ...... signals during limb patterning
@ast
Gremlin is the BMP antagonist ...... signals during limb patterning
@en
Gremlin is the BMP antagonist ...... signals during limb patterning
@nl
type
label
Gremlin is the BMP antagonist ...... signals during limb patterning
@ast
Gremlin is the BMP antagonist ...... signals during limb patterning
@en
Gremlin is the BMP antagonist ...... signals during limb patterning
@nl
prefLabel
Gremlin is the BMP antagonist ...... signals during limb patterning
@ast
Gremlin is the BMP antagonist ...... signals during limb patterning
@en
Gremlin is the BMP antagonist ...... signals during limb patterning
@nl
P2093
P3181
P356
P1433
P1476
Gremlin is the BMP antagonist ...... signals during limb patterning
@en
P2093
Lisa J Brunet
Mustafa K Khokha
Richard M Harland
P2888
P304
P3181
P356
10.1038/NG1178
P407
P577
2003-07-01T00:00:00Z