Essential function of HIPK2 in TGFbeta-dependent survival of midbrain dopamine neurons
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Homeodomain-interacting protein kinase 2 plays an important role in normal terminal erythroid differentiationHow cells switch HIPK2 on and offMethyl-CpG-binding protein 2 is phosphorylated by homeodomain-interacting protein kinase 2 and contributes to apoptosisRole of HIPK2 in kidney fibrosisHIPK2 is a new drug target for anti-fibrosis therapy in kidney diseaseHomeodomain-Interacting Protein Kinase-2: A Critical Regulator of the DNA Damage Response and the EpigenomeThe neuroprotective functions of transforming growth factor beta proteinsRole for Rab10 in Methamphetamine-Induced BehaviorA small molecule p75(NTR) ligand protects neurogenesis after traumatic brain injuryTranscriptional corepressors HIPK1 and HIPK2 control angiogenesis via TGF-β-TAK1-dependent mechanismHIPK2: a multitalented partner for transcription factors in DNA damage response and development.Homeodomain interacting protein kinase 2: a target for Alzheimer's beta amyloid leading to misfolded p53 and inappropriate cell survivalIdentification of Hipk2 as an essential regulator of white fat development.Regulation of genotoxic stress response by homeodomain-interacting protein kinase 2 through phosphorylation of cyclic AMP response element-binding protein at serine 271.Transcriptional regulation of ferritin and antioxidant genes by HIPK2 under genotoxic stress.Loss of mitochondrial fission depletes axonal mitochondria in midbrain dopamine neurons.HIPK2 represses beta-catenin-mediated transcription, epidermal stem cell expansion, and skin tumorigenesisHomeodomain interacting protein kinase 2 regulates postnatal development of enteric dopaminergic neurons and glia via BMP signaling.Cell death and the developing enteric nervous system.SMAD transcription factors are altered in cell models of HD and regulate HTT expression.Genetic ablation of homeodomain-interacting protein kinase 2 selectively induces apoptosis of cerebellar Purkinje cells during adulthood and generates an ataxic-like phenotype.Homeodomain-Interacting Protein Kinase (HPK-1) regulates stress responses and ageing in C. elegans.TGFβ signaling induces expression of Gadd45b in retinal ganglion cells.Temporal and spatial requirements of Smoothened in ventral midbrain neuronal developmentActivation of HIPK2 Promotes ER Stress-Mediated Neurodegeneration in Amyotrophic Lateral Sclerosis.Autophosphorylation and Pin1 binding coordinate DNA damage-induced HIPK2 activation and cell death.TGF-β Signaling in Dopaminergic Neurons Regulates Dendritic Growth, Excitatory-Inhibitory Synaptic Balance, and Reversal Learning.HIPK2-T566 autophosphorylation diversely contributes to UV- and doxorubicin-induced HIPK2 activation.In sickness and in health: the role of methyl-CpG binding protein 2 in the central nervous system.SUMO and Parkinson's disease.Dopaminergic Neurons and Brain Reward Pathways: From Neurogenesis to Circuit Assembly.Arsenic-Induced Activation of the Homeodomain-Interacting Protein Kinase 2 (HIPK2) to cAMP-Response Element Binding Protein (CREB) Axis.Neuronal survival in the brain: neuron type-specific mechanisms.miR-141 regulates TGF-β1-induced epithelial-mesenchymal transition through repression of HIPK2 expression in renal tubular epithelial cells.A Novel Inhibitor of Homeodomain Interacting Protein Kinase 2 Mitigates Kidney Fibrosis through Inhibition of the TGF-β1/Smad3 Pathway.TGF-β Family Signaling in Neural and Neuronal Differentiation, Development, and Function.Dopamine and α-synuclein dysfunction in Smad3 null miceLong-term oral kinetin does not protect against α-synuclein-induced neurodegeneration in rodent models of Parkinson's disease.Deficiency in Neuronal TGF-β Signaling Leads to Nigrostriatal Degeneration and Activation of TGF-β Signaling Protects against MPTP Neurotoxicity in Mice.Interactions of Wnt/beta-catenin signaling and sonic hedgehog regulate the neurogenesis of ventral midbrain dopamine neurons.
P2860
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P2860
Essential function of HIPK2 in TGFbeta-dependent survival of midbrain dopamine neurons
description
2006 nî lūn-bûn
@nan
2006 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Essential function of HIPK2 in TGFbeta-dependent survival of midbrain dopamine neurons
@ast
Essential function of HIPK2 in TGFbeta-dependent survival of midbrain dopamine neurons
@en
Essential function of HIPK2 in TGFbeta-dependent survival of midbrain dopamine neurons
@nl
type
label
Essential function of HIPK2 in TGFbeta-dependent survival of midbrain dopamine neurons
@ast
Essential function of HIPK2 in TGFbeta-dependent survival of midbrain dopamine neurons
@en
Essential function of HIPK2 in TGFbeta-dependent survival of midbrain dopamine neurons
@nl
prefLabel
Essential function of HIPK2 in TGFbeta-dependent survival of midbrain dopamine neurons
@ast
Essential function of HIPK2 in TGFbeta-dependent survival of midbrain dopamine neurons
@en
Essential function of HIPK2 in TGFbeta-dependent survival of midbrain dopamine neurons
@nl
P2093
P2860
P50
P921
P3181
P356
P1433
P1476
Essential function of HIPK2 in TGFbeta-dependent survival of midbrain dopamine neurons
@en
P2093
Amy T Tang
Jed Holtzman
Jiasheng Zhang
Joanna Hellmuth
Laurence H Tecott
Siuwah Tang
P2860
P2888
P3181
P356
10.1038/NN1816
P407
P577
2006-12-10T00:00:00Z