Force fluctuations within focal adhesions mediate ECM-rigidity sensing to guide directed cell migration.
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Fibronectin Mechanobiology Regulates TumorigenesisMechanosensitive components of integrin adhesions: Role of vinculinMechanosensing via cell-matrix adhesions in 3D microenvironmentsFocal adhesions, stress fibers and mechanical tensionMechanochemical regulation of growth cone motilityEarly events in cell spreading as a model for quantitative analysis of biomechanical eventsMechanosensitivity and compositional dynamics of cell-matrix adhesionsMechanotransduction and extracellular matrix homeostasisNew paradigms in the establishment and maintenance of gradients during directed cell migrationPhysical biology in cancer. 5. The rocky road of metastasis: the role of cytoskeletal mechanics in cell migratory response to 3D matrix topographySuper-Resolved Traction Force Microscopy (STFM)PKCδ localization at the membrane increases matrix traction force dependent on PLCγ1/EGFR signalingThe FAK-Arp2/3 interaction promotes leading edge advance and haptosensing by coupling nascent adhesions to lamellipodia actin.Synaptopodin couples epithelial contractility to α-actinin-4-dependent junction maturationSpatiotemporal dynamics of traction forces show three contraction centers in migratory neuronsForces driving epithelial wound healing.Evidence for the mechanosensor function of filamin in tissue development.The focal adhesion-localized CdGAP regulates matrix rigidity sensing and durotaxisCation type specific cell remodeling regulates attachment strengthLocal 3D matrix microenvironment regulates cell migration through spatiotemporal dynamics of contractility-dependent adhesions.The direction of stretch-induced cell and stress fiber orientation depends on collagen matrix stressRoles of endothelial A-type lamins in migration of T cells on and under endothelial layers.In-situ coupling between kinase activities and protein dynamics within single focal adhesions.Persistence of fan-shaped keratocytes is a matrix-rigidity-dependent mechanism that requires α5β1 integrin engagement.Genetic Background is a Key Determinant of Glomerular Extracellular Matrix Composition and OrganizationExtracellular rigidity sensing by talin isoform-specific mechanical linkagesSchwann cells promote endothelial cell migrationTalin tension sensor reveals novel features of focal adhesion force transmission and mechanosensitivity.Integrated micro/nanoengineered functional biomaterials for cell mechanics and mechanobiology: a materials perspective.A plastic relationship between vinculin-mediated tension and adhesion complex area defines adhesion size and lifetime.Tissue stiffness dictates development, homeostasis, and disease progression.A FAK-Cas-Rac-lamellipodin signaling module transduces extracellular matrix stiffness into mechanosensitive cell cycling.To pull or be pulled: parsing the multiple modes of mechanotransduction.Vinculin tension distributions of individual stress fibers within cell-matrix adhesions.Pancreatic stellate cells promote hapto-migration of cancer cells through collagen I-mediated signalling pathway.Actomyosin-dependent formation of the mechanosensitive talin-vinculin complex reinforces actin anchoring.Mechanotransduction of fluid stresses governs 3D cell migration.Rigidity sensing and adaptation through regulation of integrin types.Vinculin regulates osteoclast functionProbing the biomechanical contribution of the endothelium to lymphocyte migration: diapedesis by the path of least resistance.
P2860
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P2860
Force fluctuations within focal adhesions mediate ECM-rigidity sensing to guide directed cell migration.
description
2012 nî lūn-bûn
@nan
2012 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Force fluctuations within foca ...... guide directed cell migration
@nl
Force fluctuations within foca ...... guide directed cell migration.
@ast
Force fluctuations within foca ...... guide directed cell migration.
@en
type
label
Force fluctuations within foca ...... guide directed cell migration
@nl
Force fluctuations within foca ...... guide directed cell migration.
@ast
Force fluctuations within foca ...... guide directed cell migration.
@en
prefLabel
Force fluctuations within foca ...... guide directed cell migration
@nl
Force fluctuations within foca ...... guide directed cell migration.
@ast
Force fluctuations within foca ...... guide directed cell migration.
@en
P2093
P2860
P3181
P1433
P1476
Force fluctuations within foca ...... guide directed cell migration.
@en
P2093
Ana M Pasapera
Benedikt Sabass
Sergey V Plotnikov
P2860
P304
P3181
P356
10.1016/J.CELL.2012.11.034
P407
P50
P577
2012-12-01T00:00:00Z