Bcl-2 expression promotes B- but not T-lymphoid development in scid mice
about
The intracellular distribution and pattern of expression of Mcl-1 overlap with, but are not identical to, those of Bcl-2The BCL2A1 gene as a pre-T cell receptor-induced regulator of thymocyte survivalInactivation of S6 ribosomal protein gene in T lymphocytes activates a p53-dependent checkpoint response.Phospholipase Cgamma2 provides survival signals via Bcl2 and A1 in different subpopulations of B cellsGenetic control of programmed cell death during animal development.Negative selection of semimature CD4(+)8(-)HSA+ thymocytes requires the BH3-only protein Bim but is independent of death receptor signaling.Deletion of immunoglobulin beta in developing B cells leads to cell death.Plasmacytomagenesis in Eμ-v-abl transgenic mice is accelerated when apoptosis is restrained.Role of interleukin-7 in T-cell development from hematopoietic stem cells.The anti-apoptotic activities of Rel and RelA required during B-cell maturation involve the regulation of Bcl-2 expression.Formation of coding joints in V(D)J recombination-inducible severe combined immune deficient pre-B cell lines.The control of apoptosis in lymphocyte selection.Peripheral B-cell maturation: the intersection of selection and homeostasis.The Emu-bcl-2 transgene enhances antigen-induced germinal center formation in both BALB/c and SJL mice but causes age-dependent germinal center hyperplasia only in the lymphoma-prone SJL strainThymocyte-targeted overexpression of xiap transgene disrupts T lymphoid apoptosis and maturationVprBP Is Required for Efficient Editing and Selection of Igκ+ B Cells, but Is Dispensable for Igλ+ and Marginal Zone B Cell Maturation and Selection.Allelic exclusion of the T cell receptor beta locus requires the SH2 domain-containing leukocyte protein (SLP)-76 adaptor protein.bcl-2 transgene expression inhibits apoptosis in the germinal center and reveals differences in the selection of memory B cells and bone marrow antibody-forming cellsKu70 is required for DNA repair but not for T cell antigen receptor gene recombination In vivo.Enforced Bcl-2 expression inhibits antigen-mediated clonal elimination of peripheral B cells in an antigen dose-dependent manner and promotes receptor editing in autoreactive, immature B cells.Unexpected rearrangement and expression of the immunoglobulin lambda1 locus in scid mice.Conditional Disruption of Raptor Reveals an Essential Role for mTORC1 in B Cell Development, Survival, and Metabolism.Targeting the mitochondrial apoptotic pathway: a preferred approach in hematologic malignancies?Cell death and thymic tolerance.IL-7Ralpha and E47: independent pathways required for development of multipotent lymphoid progenitors.Teaching cell biology in the large-enrollment classroom: methods to promote analytical thinking and assessment of their effectivenessFADD/MORT1 regulates the pre-TCR checkpoint and can function as a tumour suppressor.EBI2 overexpression in mice leads to B1 B-cell expansion and chronic lymphocytic leukemia-like B-cell malignancies.Analysis of the role of bcl-2 in apoptosis.BCL2 and JUNB abnormalities in primary cutaneous lymphomas.Specific transcription of the unrearranged TCR V beta 8.2 gene in lymphoid tissues occurs independently of V(D)J rearrangement.Role for Ets-2(Thr-72) transcription factor in stage-specific thymocyte development and survivalJanus-kinase-3-dependent signals induce chromatin remodeling at the Ifng locus during T helper 1 cell differentiation.Cell cycle progression following naive T cell activation is independent of Jak3/common gamma-chain cytokine signals.Early function of Pax5 (BSAP) before the pre-B cell receptor stage of B lymphopoiesis.Thymic epithelial β-catenin is required for adult thymic homeostasis and function.Brca1 required for T cell lineage development but not TCR loci rearrangement.
P2860
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P2860
Bcl-2 expression promotes B- but not T-lymphoid development in scid mice
description
1994 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
1994 թվականի մարտին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Nature
@fr
artículu científicu espublizáu en 1994
@ast
scientific journal article
@en
vedecký článok (publikovaný 1994/03/31)
@sk
vědecký článek publikovaný v roce 1994
@cs
wetenschappelijk artikel (gepubliceerd op 1994/03/31)
@nl
наукова стаття, опублікована в березні 1994
@uk
مقالة علمية (نشرت في 31-3-1994)
@ar
name
Bcl-2 expression promotes B- but not T-lymphoid development in scid mice
@ast
Bcl-2 expression promotes B- but not T-lymphoid development in scid mice
@en
Bcl-2 expression promotes B- but not T-lymphoid development in scid mice
@nl
type
label
Bcl-2 expression promotes B- but not T-lymphoid development in scid mice
@ast
Bcl-2 expression promotes B- but not T-lymphoid development in scid mice
@en
Bcl-2 expression promotes B- but not T-lymphoid development in scid mice
@nl
prefLabel
Bcl-2 expression promotes B- but not T-lymphoid development in scid mice
@ast
Bcl-2 expression promotes B- but not T-lymphoid development in scid mice
@en
Bcl-2 expression promotes B- but not T-lymphoid development in scid mice
@nl
P356
P1433
P1476
Bcl-2 expression promotes B- but not T-lymphoid development in scid mice
@en
P2093
A. W. Harris
L. M. Corcoran
P2888
P304
P356
10.1038/368457A0
P407
P577
1994-03-31T00:00:00Z
P6179
1045984381