Cloning and characterization of subunits of the T-cell receptor and murine leukemia virus enhancer core-binding factor
about
Activation of AML1-mediated transcription by MOZ and inhibition by the MOZ-CBP fusion proteinIsoforms of the Ets transcription factor NERF/ELF-2 physically interact with AML1 and mediate opposing effects on AML1-mediated transcription of the B cell-specific blk geneA novel transcript encoding an N-terminally truncated AML1/PEBP2 alphaB protein interferes with transactivation and blocks granulocytic differentiation of 32Dcl3 myeloid cellsSubcellular localization of the alpha and beta subunits of the acute myeloid leukemia-linked transcription factor PEBP2/CBFThe AML1-MTG8 leukemic fusion protein forms a complex with a novel member of the MTG8(ETO/CDR) family, MTGR1Disruption of the Cbfa2 gene causes necrosis and hemorrhaging in the central nervous system and blocks definitive hematopoiesisAlternative splicing and genomic structure of the AML1 gene involved in acute myeloid leukemiaThe inv(16) encodes an acute myeloid leukemia 1 transcriptional corepressorCore Binding Factor Acute Myeloid Leukemia: New Prognostic Categories and Therapeutic OpportunitiesRole of RUNX2 in Breast CarcinogenesisA mechanism of repression by acute myeloid leukemia-1, the target of multiple chromosomal translocations in acute leukemiaAML1 (CBFalpha2) cooperates with B cell-specific activating protein (BSAP/PAX5) in activation of the B cell-specific BLK gene promoterNuclear import and subnuclear localization of the proto-oncoprotein ETO (MTG8)AML1 interconnected pathways of leukemogenesisInteractions between the leukaemia-associated ETO homologues of nuclear repressor proteinsThe RUNX genes: gain or loss of function in cancerTransforming growth factor-beta stimulates p300-dependent RUNX3 acetylation, which inhibits ubiquitination-mediated degradationRunx2: a master organizer of gene transcription in developing and maturing osteoblastsMaturational disturbance of chondrocytes in Cbfa1-deficient miceExpression of the Runt domain-encoding PEBP2 alpha genes in T cells during thymic developmentThe mood-stabilizing agents lithium and valproate robustly increase the levels of the neuroprotective protein bcl-2 in the CNSRunt-related transcription factor 1 regulates luteinized hormone-induced prostaglandin-endoperoxide synthase 2 expression in rat periovulatory granulosa cellsAML1 is expressed in skeletal muscle and is regulated by innervationMutagenesis of the Runt domain defines two energetic hot spots for heterodimerization with the core binding factor beta subunitHematopoiesis in the fetal liver is impaired by targeted mutagenesis of a gene encoding a non-DNA binding subunit of the transcription factor, polyomavirus enhancer binding protein 2/core binding factorPI(2)PE: A Suite of Web Servers for Predictions Ranging From Protein Structure to Binding Kinetics.CBFbeta is critical for AML1-ETO and TEL-AML1 activity.A mutation in the S-switch region of the Runt domain alters the dynamics of an allosteric network responsible for CBFbeta regulation.The E47 transcription factor binds to the enhancer sequences of recombinant murine leukemia viruses and influences enhancer functionAbsence of fetal liver hematopoiesis in mice deficient in transcriptional coactivator core binding factor beta.A novel gene, FGA7, is fused to RUNX1/AML1 in a t(4;21)(q28;q22) in a patient with T-cell acute lymphoblastic leukemia.Mouse glutaredoxin - cDNA cloning, high level expression in E. coli and its possible implication in redox regulation of the DNA binding activity in transcription factor PEBP2.The common retroviral insertion locus Dsi1 maps 30 kilobases upstream of the P1 promoter of the murine Runx3/Cbfa3/Aml2 geneIntegrative analysis of RUNX1 downstream pathways and target genes.Transcription factors RUNX1 and RUNX3 in the induction and suppressive function of Foxp3+ inducible regulatory T cellsCbfb/Runx1 repression-independent blockage of differentiation and accumulation of Csf2rb-expressing cells by Cbfb-MYH11.The AML1-ETO chimaeric transcription factor in acute myeloid leukaemia: biology and clinical significance.Multiple functional domains of AML1: PU.1 and C/EBPalpha synergize with different regions of AML1The leukemic protein core binding factor beta (CBFbeta)-smooth-muscle myosin heavy chain sequesters CBFalpha2 into cytoskeletal filaments and aggregatesIn vivo footprinting of the enhancer sequences in the upstream long terminal repeat of Moloney murine leukemia virus: differential binding of nuclear factors in different cell types
P2860
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P2860
Cloning and characterization of subunits of the T-cell receptor and murine leukemia virus enhancer core-binding factor
description
1993 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
1993 թվականի հունիսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 1993
@ast
im Juni 1993 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 1993/06/01)
@sk
vědecký článek publikovaný v roce 1993
@cs
wetenschappelijk artikel (gepubliceerd op 1993/06/01)
@nl
наукова стаття, опублікована в червні 1993
@uk
научни чланак (објављен 1993/06/01)
@sr
name
Cloning and characterization o ...... s enhancer core-binding factor
@ast
Cloning and characterization o ...... s enhancer core-binding factor
@en
Cloning and characterization o ...... s enhancer core-binding factor
@nl
type
label
Cloning and characterization o ...... s enhancer core-binding factor
@ast
Cloning and characterization o ...... s enhancer core-binding factor
@en
Cloning and characterization o ...... s enhancer core-binding factor
@nl
prefLabel
Cloning and characterization o ...... s enhancer core-binding factor
@ast
Cloning and characterization o ...... s enhancer core-binding factor
@en
Cloning and characterization o ...... s enhancer core-binding factor
@nl
P2093
P2860
P921
P356
P1476
Cloning and characterization o ...... s enhancer core-binding factor
@en
P2093
B. E. Crute
I. N. Melnikova
N. A. Speck
S. R. Keller
P2860
P304
P356
10.1128/MCB.13.6.3324
P407
P577
1993-06-01T00:00:00Z