Targeted deletion of the tub mouse obesity gene reveals that tubby is a loss-of-function mutation
about
Microtubule-associated protein 1A is a modifier of tubby hearing (moth1).Neuropeptide Y in normal eating and in genetic and dietary-induced obesityMouse hitchhiker mutants have spina bifida, dorso-ventral patterning defects and polydactyly: identification of Tulp3 as a novel negative regulator of the Sonic hedgehog pathwayThyroid hormone regulates the obesity gene tubA model for obesity and gigantism due to disruption of the Ankrd26 geneTubby is required for trafficking G protein-coupled receptors to neuronal ciliaThe tubby family proteins.Deafness and retinal degeneration in a novel USH1C knock-in mouse modelMolecular mechanisms underlying cochlear degeneration in the tubby mouse and the therapeutic effect of sulforaphane.Polymorphisms of the TUB gene are associated with body composition and eating behavior in middle-aged women.Sensory perception of food and insulin-like signals influence seizure susceptibility.From the cytoplasm into the cilium: bon voyage.Tub has a key role in insulin and leptin signaling and action in vivo in hypothalamic nucleiCentral regulation of metabolism by protein tyrosine phosphatasesPredisposition to late-onset obesity in GIRK4 knockout mice.Microarray analysis of differentially expressed genes in the brains of tubby mice.Naturally occurring animal models with outer retina phenotypes.C-terminally mutated tubby protein accumulates in aggresomes.Phagocyte dysfunction, tissue aging and degeneration.Cholesterol gallstone formation in overweight mice establishes that obesity per se is not linked directly to cholelithiasis risk.Recent Progress in the Understanding of Obesity: Contributions of Genome-Wide Association Studies.TUB gene expression in hypothalamus and adipose tissue and its association with obesity in humans.Abnormal cholinergic and GABAergic vascular innervation in the hypothalamic arcuate nucleus of obese tub/tub mice.Polygenic control of Caenorhabditis elegans fat storage.Defective carbohydrate metabolism in mice homozygous for the tubby mutation.The Human Obesity Gene Map: The 2004 Update
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P2860
Targeted deletion of the tub mouse obesity gene reveals that tubby is a loss-of-function mutation
description
2000 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2000
@ast
im Februar 2000 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2000/02/01)
@sk
vědecký článek publikovaný v roce 2000
@cs
wetenschappelijk artikel (gepubliceerd op 2000/02/01)
@nl
наукова стаття, опублікована в лютому 2000
@uk
مقالة علمية (نشرت في فبراير 2000)
@ar
name
Targeted deletion of the tub m ...... is a loss-of-function mutation
@ast
Targeted deletion of the tub m ...... is a loss-of-function mutation
@en
Targeted deletion of the tub m ...... is a loss-of-function mutation
@nl
type
label
Targeted deletion of the tub m ...... is a loss-of-function mutation
@ast
Targeted deletion of the tub m ...... is a loss-of-function mutation
@en
Targeted deletion of the tub m ...... is a loss-of-function mutation
@nl
prefLabel
Targeted deletion of the tub m ...... is a loss-of-function mutation
@ast
Targeted deletion of the tub m ...... is a loss-of-function mutation
@en
Targeted deletion of the tub m ...... is a loss-of-function mutation
@nl
P2093
P2860
P1476
Targeted deletion of the tub m ...... is a loss-of-function mutation
@en
P2093
A. Moriarty
C. A. Lynch
H. Stubdal
J. D. Deeds
J. H. Dunmore
O. Charlat
R. Kapeller
P2860
P304
P356
10.1128/MCB.20.3.878-882.2000
P407
P577
2000-02-01T00:00:00Z