Mice lacking alpha 1 (IX) collagen develop noninflammatory degenerative joint disease
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Developmental regulation of mRNA species for types II, IX and XI collagens during mouse embryogenesisCartilage oligomeric matrix protein-deficient mice have normal skeletal development.COL9A3: A third locus for multiple epiphyseal dysplasia.Attenuation of osteoarthritis progression by reduction of discoidin domain receptor 2 in miceDecreased physical function and increased pain sensitivity in mice deficient for type IX collagen.A mutation in the alpha 3 chain of type IX collagen causes autosomal dominant multiple epiphyseal dysplasia with mild myopathyThe role of structural genes in the pathogenesis of osteoarthritic disordersCrystal structure of the N-terminal NC4 domain of collagen IX, a zinc binding member of the laminin-neurexin-sex hormone binding globulin (LNS) domain familyComplete sequence of the 23-kilobase human COL9A3 gene. Detection of Gly-X-Y triplet deletions that represent neutral variantsClinical phenotype and molecular diagnosis of multiple epiphyseal dysplasia with relative hip sparing during childhood (EDM2)Regulation of human COL9A1 gene expression. Activation of the proximal promoter region by SOX9Skeletal abnormalities in mice lacking extracellular matrix proteins, thrombospondin-1, thrombospondin-3, thrombospondin-5, and type IX collagenTargeted disruption of Col11a2 produces a mild cartilage phenotype in transgenic mice: comparison with the human disorder otospondylomegaepiphyseal dysplasia (OSMED)Type III collagen is crucial for collagen I fibrillogenesis and for normal cardiovascular developmentThe extracellular matrix in development and morphogenesis: a dynamic view.Type IX collagen deficiency enhances the binding of cartilage-specific antibodies and arthritis severity.Genetics and osteoarthritis: exposing the iceberg.Genetic linkage analysis of 14 candidate gene loci in a family with autosomal dominant osteoarthritis without dysplasia.The elusive functions of proteoglycans: in vivo veritasComprehensive profiling of cartilage extracellular matrix formation and maturation using sequential extraction and label-free quantitative proteomics.Type IX collagen interacts with fibronectin providing an important molecular bridge in articular cartilage.Locomotor activity and gait in aged mice deficient for type IX collagenCollagens: building blocks at the end of the development line.Hypertrophic differentiation of chondrocytes in osteoarthritis: the developmental aspect of degenerative joint disordersThe fibril-associated collagen IX provides a novel mechanism for cell adhesion to cartilaginous matrix.Association of reduced type IX collagen gene expression in human osteoarthritic chondrocytes with epigenetic silencing by DNA hypermethylationTGF-ß1 enhances the BMP-2-induced chondrogenesis of bovine synovial explants and arrests downstream differentiation at an early stage of hypertrophyEpigenetic regulation during fetal femur development: DNA methylation matters.Biomechanical spinal growth modulation and progressive adolescent scoliosis--a test of the 'vicious cycle' pathogenetic hypothesis: summary of an electronic focus group debate of the IBSE.COL9A1 gene polymorphism is associated with Kashin-Beck disease in a northwest Chinese Han populationLifelong voluntary joint loading increases osteoarthritis in mice housing a deletion mutation in type II procollagen gene, and slightly also in non-transgenic mice.Cartilage morphogenetic proteins: role in joint development, homoeostasis, and regenerationUnique matrix structure in the rough endoplasmic reticulum cisternae of pseudoachondroplasia chondrocytes.Epigenetics and Osteoarthritis.A short isoform of Col9a1 supports alveolar bone repair.Severe Extracellular Matrix Abnormalities and Chondrodysplasia in Mice Lacking Collagen Prolyl 4-Hydroxylase Isoenzyme II in Combination with a Reduced Amount of Isoenzyme I.Epigenetic mechanisms underlying the aberrant catabolic and anabolic activities of osteoarthritic chondrocytes.Lessons from genetic forms of osteoarthritis for the pathogenesis of the diseaseNeural tube opening and abnormal extraembryonic membrane development in SEC23A deficient mice.Large and small splice variants of collagen XII: differential expression and ligand binding.
P2860
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P2860
Mice lacking alpha 1 (IX) collagen develop noninflammatory degenerative joint disease
description
1994 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
1994 թվականի մայիսին հրատարակված գիտական հոդված
@hy
article publié dans les Procee ...... f the United States of America
@fr
artículu científicu espublizáu en 1994
@ast
im Mai 1994 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 1994/05/24)
@sk
vědecký článek publikovaný v roce 1994
@cs
wetenschappelijk artikel (gepubliceerd op 1994/05/24)
@nl
наукова стаття, опублікована в травні 1994
@uk
name
Mice lacking alpha 1 (IX) collagen develop noninflammatory degenerative joint disease
@ast
Mice lacking alpha 1 (IX) collagen develop noninflammatory degenerative joint disease
@en
Mice lacking alpha 1 (IX) collagen develop noninflammatory degenerative joint disease
@nl
type
label
Mice lacking alpha 1 (IX) collagen develop noninflammatory degenerative joint disease
@ast
Mice lacking alpha 1 (IX) collagen develop noninflammatory degenerative joint disease
@en
Mice lacking alpha 1 (IX) collagen develop noninflammatory degenerative joint disease
@nl
prefLabel
Mice lacking alpha 1 (IX) collagen develop noninflammatory degenerative joint disease
@ast
Mice lacking alpha 1 (IX) collagen develop noninflammatory degenerative joint disease
@en
Mice lacking alpha 1 (IX) collagen develop noninflammatory degenerative joint disease
@nl
P2093
P2860
P356
P1476
Mice lacking alpha 1 (IX) collagen develop noninflammatory degenerative joint disease
@en
P2093
B. R. Olsen
J. Dausman
M. T. McCarthy
P. N. Schnegelsberg
R. Fässler
R. Jaenisch
Y. Muragaki
P2860
P304
P356
10.1073/PNAS.91.11.5070
P407
P577
1994-05-24T00:00:00Z