Hematopoietic tissue-specific expression of mouse Neil3 for endonuclease VIII-like protein
about
8-Oxoguanine DNA glycosylase (OGG1) deficiency increases susceptibility to obesity and metabolic dysfunctionDNA glycosylases: in DNA repair and beyondNew perspectives on oxidized genome damage and repair inhibition by pro-oxidant metals in neurological diseasesThe Fpg/Nei family of DNA glycosylases: substrates, structures, and search for damageBase excision repair and cancerStructural Characterization of a Mouse Ortholog of Human NEIL3 with a Marked Preference for Single-Stranded DNAMouse RS21-C6 is a mammalian 2'-deoxycytidine 5'-triphosphate pyrophosphohydrolase that prefers 5-iodocytosineThe mouse ortholog of NEIL3 is a functional DNA glycosylase in vitro and in vivoNo cancer predisposition or increased spontaneous mutation frequencies in NEIL DNA glycosylases-deficient miceEndonuclease VIII-like 3 (Neil3) DNA glycosylase promotes neurogenesis induced by hypoxia-ischemia.Expression and purification of active mouse and human NEIL3 proteins.Neil2-null Mice Accumulate Oxidized DNA Bases in the Transcriptionally Active Sequences of the Genome and Are Susceptible to Innate InflammationBase excision repair in physiology and pathology of the central nervous systemNeil3, the final frontier for the DNA glycosylases that recognize oxidative damage.Base excision repair, aging and health span.Deficiency of base excision repair enzyme NEIL3 drives increased predisposition to autoimmunity.Neil3 induced neurogenesis protects against prion disease during the clinical phase.DNA glycosylases search for and remove oxidized DNA bases.Formation and processing of DNA damage substrates for the hNEIL enzymes.NEIL3 Repairs Telomere Damage during S Phase to Secure Chromosome Segregation at Mitosis.Neil3-dependent base excision repair regulates lipid metabolism and prevents atherosclerosis in Apoe-deficient mice.Widespread distribution of DNA glycosylases removing oxidative DNA lesions in human and rodent brains.Expression patterns of Neil3 during embryonic brain development and neoplasia.Replication-Dependent Unhooking of DNA Interstrand Cross-Links by the NEIL3 Glycosylase.TET-mediated oxidation of methylcytosine causes TDG or NEIL glycosylase dependent gene reactivation.Cancer-related PRUNE2 protein is associated with nucleotides and is highly expressed in mature nerve tissues.Loss of NEIL3 DNA glycosylase markedly increases replication associated double strand breaks and enhances sensitivity to ATR inhibitor in glioblastoma cells.
P2860
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P2860
Hematopoietic tissue-specific expression of mouse Neil3 for endonuclease VIII-like protein
description
2005 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2005
@ast
im Dezember 2005 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2005/12/01)
@sk
vědecký článek publikovaný v roce 2005
@cs
wetenschappelijk artikel (gepubliceerd op 2005/12/01)
@nl
наукова стаття, опублікована в грудні 2005
@uk
مقالة علمية (نشرت في ديسمبر 2005)
@ar
name
Hematopoietic tissue-specific ...... endonuclease VIII-like protein
@ast
Hematopoietic tissue-specific ...... endonuclease VIII-like protein
@en
Hematopoietic tissue-specific ...... endonuclease VIII-like protein
@nl
type
label
Hematopoietic tissue-specific ...... endonuclease VIII-like protein
@ast
Hematopoietic tissue-specific ...... endonuclease VIII-like protein
@en
Hematopoietic tissue-specific ...... endonuclease VIII-like protein
@nl
prefLabel
Hematopoietic tissue-specific ...... endonuclease VIII-like protein
@ast
Hematopoietic tissue-specific ...... endonuclease VIII-like protein
@en
Hematopoietic tissue-specific ...... endonuclease VIII-like protein
@nl
P2093
P3181
P356
P1476
Hematopoietic tissue-specific ...... endonuclease VIII-like protein
@en
P2093
Daisuke Tsuchimoto
Kumiko Torisu
Yoshinori Ohnishi
P304
P3181
P356
10.1093/JB/MVI168
P577
2005-12-01T00:00:00Z