The distinct spectra of tumor-associated Apc mutations in mismatch repair-deficient Apc1638N mice define the roles of MSH3 and MSH6 in DNA repair and intestinal tumorigenesis
about
Differing patterns of genetic instability in mice deficient in the mismatch repair genes Pms2, Mlh1, Msh2, Msh3 and Msh6Molecular models for the tissue specificity of DNA mismatch repair-deficient carcinogenesisColorectal cancer models for novel drug discoveryNovel roles for MLH3 deficiency and TLE6-like amplification in DNA mismatch repair-deficient gastrointestinal tumorigenesis and progression.Genetic mechanisms in Apc-mediated mammary tumorigenesisMouse models of colorectal cancer.Murine models of colorectal cancer.Mouse models expressing human carcinoembryonic antigen (CEA) as a transgene: evaluation of CEA-based cancer vaccines.Haploinsufficiency of Flap endonuclease (Fen1) leads to rapid tumor progressionBoth hMutSα and hMutSß DNA mismatch repair complexes participate in 5-fluorouracil cytotoxicity.Mbd4 inactivation increases Cright-arrowT transition mutations and promotes gastrointestinal tumor formation.Msh6 protects mature B cells from lymphoma by preserving genomic stability.Increased incidence of endometrioid tumors caused by aberrations in E-cadherin promoter of mismatch repair-deficient mice.Clonal structure of carcinogen-induced intestinal tumors in miceAdenomatous polyposis coli interacts with flap endonuclease 1 to block its nuclear entry and functionSomatic mutations of APC gene in carcinomas from hereditary non-polyposis colorectal cancer patients.Alkylation-induced colon tumorigenesis in mice deficient in the Mgmt and Msh6 proteinsMouse models of DNA mismatch repair in cancer research.Polyclonal tumors in the mammalian intestine: are interactions among multiple initiated clones necessary for tumor initiation, growth, and progression?Interaction between APC and Fen1 during breast carcinogenesis.Transformation of epithelial cells through recruitment leads to polyclonal intestinal tumorsMolecular characterisation of murine acute myeloid leukaemia induced by 56Fe ion and 137Cs gamma ray irradiation.Interaction of Muc2 and Apc on Wnt signaling and in intestinal tumorigenesis: potential role of chronic inflammationAPC and its modifiers in colon cancer.The MutSβ complex is a modulator of p53-driven tumorigenesis through its functions in both DNA double-strand break repair and mismatch repairWhat are the best routes to effectively model human colorectal cancer?Acidic tumor microenvironment downregulates hMLH1 but does not diminish 5-fluorouracil chemosensitivity.The MUTYH base excision repair gene protects against inflammation-associated colorectal carcinogenesisA systems approach defining constraints of the genome architecture on lineage selection and evolvability during somatic cancer evolution
P2860
Q22242924-C33CE535-A00E-4C62-8A0E-47731C182433Q25257401-ACCA2EFD-7E13-4993-AB20-24412597EE8AQ26795724-97948D6D-ECED-4DF6-B88A-485903B4DDDCQ33343446-4D2C47D5-D19D-4E87-8845-2CB43B6CBA10Q33406237-837CBD3B-4A62-4488-AF83-539297F68F42Q33579734-EC359719-E95D-417A-B48D-C713062225A6Q33640905-27B53266-CEA4-434A-99D3-E94290111272Q33754989-1B16BE56-D43A-4D6A-9D86-596C67BA94D0Q34098053-40896C13-B73E-4D01-A25E-F99FC759EFE1Q34099011-E432ADBE-DB9B-45A1-87A0-B250F8F025A2Q34157868-0D795F12-FFFD-4FC3-92FF-FFD3FDE1A60DQ34254602-86ABCC26-AA26-4000-A1CA-45FBC18F7364Q35083547-3098D8F3-6841-4AD6-B108-E9CA6BFE16A0Q35561929-30D83C76-3818-40C5-B154-BCB6DC32EC6BQ36088175-D6BE7A1D-81DB-4015-B330-C7E8899CD97BQ36502627-9D28C469-4720-423A-A488-C4829333CAD4Q36570190-B293ACD9-A465-4948-814B-977AF6D4A501Q36583537-32B03AC1-3C9E-4BD5-8C1D-405D9D18F595Q36666183-BE9B95B2-4217-4683-8E0D-096967FD7129Q36853315-C94E141F-9F3D-492D-9114-3F86F2C898BFQ37010862-9153564C-457F-4D6E-ABD1-F74AD742C8DBQ37026983-DF36ADE3-3769-4935-837A-BF1DB434ACA6Q37232595-F3707F46-09C5-46D8-A424-A83695C7D60EQ37635945-37DEA2AB-F730-4625-9887-7278EC831CB8Q37653026-7D1922B7-3CFD-4857-9F0E-296A3D0B01DAQ38087005-B87D653A-897C-4191-B5E7-8EEF567C7449Q39156478-3D7C845C-9668-461F-B1C4-644193869055Q41141273-A5911D5F-D599-4BBB-B6A8-FDFBAFDF8BBEQ41882366-1D1B122A-DDC3-4F9C-BA61-CF45EB2F3293
P2860
The distinct spectra of tumor-associated Apc mutations in mismatch repair-deficient Apc1638N mice define the roles of MSH3 and MSH6 in DNA repair and intestinal tumorigenesis
description
2001 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2001
@ast
im November 2001 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2001/11/01)
@sk
vědecký článek publikovaný v roce 2001
@cs
wetenschappelijk artikel (gepubliceerd op 2001/11/01)
@nl
наукова стаття, опублікована в листопаді 2001
@uk
مقالة علمية (نشرت في نوفمبر 2001)
@ar
name
The distinct spectra of tumor- ...... r and intestinal tumorigenesis
@ast
The distinct spectra of tumor- ...... r and intestinal tumorigenesis
@en
The distinct spectra of tumor- ...... r and intestinal tumorigenesis
@nl
type
label
The distinct spectra of tumor- ...... r and intestinal tumorigenesis
@ast
The distinct spectra of tumor- ...... r and intestinal tumorigenesis
@en
The distinct spectra of tumor- ...... r and intestinal tumorigenesis
@nl
prefLabel
The distinct spectra of tumor- ...... r and intestinal tumorigenesis
@ast
The distinct spectra of tumor- ...... r and intestinal tumorigenesis
@en
The distinct spectra of tumor- ...... r and intestinal tumorigenesis
@nl
P2093
P921
P1433
P1476
The distinct spectra of tumor- ...... r and intestinal tumorigenesis
@en
P2093
A. M. Brown
E. Avdievich
M. Kuraguchi
R. D. Kolodner
R. Kucherlapati
W. Edelmann
P304
P407
P577
2001-11-01T00:00:00Z