Enhanced Ca2+ transport and muscle relaxation in skeletal muscle from sarcolipin-null mice
about
Crystal structures of the calcium pump and sarcolipin in the Mg2+-bound E1 stateA micropeptide encoded by a putative long noncoding RNA regulates muscle performanceA peptide encoded by a transcript annotated as long noncoding RNA enhances SERCA activity in muscleThe role of skeletal-muscle-based thermogenic mechanisms in vertebrate endothermySarcolipin is a newly identified regulator of muscle-based thermogenesis in mammals.Co-expression of SERCA isoforms, phospholamban and sarcolipin in human skeletal muscle fibersSarcolipin Is a Key Determinant of the Basal Metabolic Rate, and Its Overexpression Enhances Energy Expenditure and Resistance against Diet-induced Obesity.Sarcolipin deletion exacerbates soleus muscle atrophy and weakness in phospholamban overexpressing mice.Sarcolipin protein interaction with sarco(endo)plasmic reticulum Ca2+ ATPase (SERCA) is distinct from phospholamban protein, and only sarcolipin can promote uncoupling of the SERCA pump.Diaphragm assessment in mice overexpressing phospholamban in slow-twitch type I muscle fibers.Mitogen-activated protein kinase-activated protein kinases 2 and 3 regulate SERCA2a expression and fiber type composition to modulate skeletal muscle and cardiomyocyte function.Sarcolipin trumps β-adrenergic receptor signaling as the favored mechanism for muscle-based diet-induced thermogenesis.Role of SERCA Pump in Muscle Thermogenesis and Metabolism.Persistence of diet-induced obesity despite access to voluntary activity in mice lacking sarcolipin.Mitsugumin 53 attenuates the activity of sarcoplasmic reticulum Ca(2+)-ATPase 1a (SERCA1a) in skeletal muscle.The effects of sarcolipin over-expression in mouse skeletal muscle on metabolic activity.Reducing sarcolipin expression mitigates Duchenne muscular dystrophy and associated cardiomyopathy in mice.Ablation of sarcolipin decreases the energy requirements for Ca2+ transport by sarco(endo)plasmic reticulum Ca2+-ATPases in resting skeletal muscle.Increased sarcolipin expression and decreased sarco(endo)plasmic reticulum Ca2+ uptake in skeletal muscles of mouse models of Duchenne muscular dystrophy.Parvalbumin is overexpressed in the late phase of pharmacological preconditioning in skeletal muscle.Sarcoplasmic Reticulum Phospholipid Fatty Acid Composition and Sarcolipin Content in Rat Skeletal Muscle.Effects of sarcolipin deletion on skeletal muscle adaptive responses to functional overload and unload.Sarcolipin expression is not required for the mitochondrial enzymatic response to physical activity or diet.Sarcolipin knockout mice fed a high-fat diet exhibit altered indices of adipose tissue inflammation and remodeling.
P2860
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P2860
Enhanced Ca2+ transport and muscle relaxation in skeletal muscle from sarcolipin-null mice
description
2011 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2011
@ast
im Oktober 2011 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2011/10/01)
@sk
vědecký článek publikovaný v roce 2011
@cs
wetenschappelijk artikel (gepubliceerd op 2011/10/01)
@nl
наукова стаття, опублікована в жовтні 2011
@uk
مقالة علمية (نشرت في أكتوبر 2011)
@ar
name
Enhanced Ca2+ transport and mu ...... scle from sarcolipin-null mice
@ast
Enhanced Ca2+ transport and mu ...... scle from sarcolipin-null mice
@en
Enhanced Ca2+ transport and mu ...... scle from sarcolipin-null mice
@nl
type
label
Enhanced Ca2+ transport and mu ...... scle from sarcolipin-null mice
@ast
Enhanced Ca2+ transport and mu ...... scle from sarcolipin-null mice
@en
Enhanced Ca2+ transport and mu ...... scle from sarcolipin-null mice
@nl
prefLabel
Enhanced Ca2+ transport and mu ...... scle from sarcolipin-null mice
@ast
Enhanced Ca2+ transport and mu ...... scle from sarcolipin-null mice
@en
Enhanced Ca2+ transport and mu ...... scle from sarcolipin-null mice
@nl
P2093
P2860
P3181
P1476
Enhanced Ca2+ transport and mu ...... scle from sarcolipin-null mice
@en
P2093
A. Russell Tupling
Anthony O. Gramolini
Chris Vigna
Darin Bloemberg
David H. MacLennan
Dawar Hussain
Eric Bombardier
Gopal J. Babu
Joe Quadrilatero
Maria G. Trivieri
P2860
P304
P3181
P356
10.1152/AJPCELL.00409.2010
P577
2011-10-01T00:00:00Z