Genome-wide characterization of Foxa2 targets reveals upregulation of floor plate genes and repression of ventrolateral genes in midbrain dopaminergic progenitors
about
LMX1B is part of a transcriptional complex with PSPC1 and PSF.Embryonic development of selectively vulnerable neurons in Parkinson's disease.Selection Based on FOXA2 Expression Is Not Sufficient to Enrich for Dopamine Neurons From Human Pluripotent Stem CellsReconstruction of the gene regulatory network involved in the sonic hedgehog pathway with a potential role in early development of the mouse brainTranscription factors FOXA1 and FOXA2 maintain dopaminergic neuronal properties and control feeding behavior in adult mice.Excessive Wnt/beta-catenin signaling promotes midbrain floor plate neurogenesis, but results in vacillating dopamine progenitors.Prion protein localizes at the ciliary base during neural and cardiovascular development, and its depletion affects α-tubulin post-translational modificationsNeural-specific Sox2 input and differential Gli-binding affinity provide context and positional information in Shh-directed neural patterning.In vitro generation of mature midbrain-type dopamine neurons by adjusting exogenous Nurr1 and Foxa2 expressions to their physiologic patterns.Cellular programming and reprogramming: sculpting cell fate for the production of dopamine neurons for cell therapy.Transcriptional regulation of guidance at the midline and in motor circuits.Directed midbrain and spinal cord neurogenesis from pluripotent stem cells to model development and disease in a dish.Molecular mechanisms of dopaminergic subset specification: fundamental aspects and clinical perspectives.Genetic control of midbrain dopaminergic neuron development.Genome-wide characterisation of Foxa1 binding sites reveals several mechanisms for regulating neuronal differentiation in midbrain dopamine cellsArx together with FoxA2, regulates Shh floor plate expression.IAP-Based Cell Sorting Results in Homogeneous Transplantable Dopaminergic Precursor Cells Derived from Human Pluripotent Stem Cells.Transcriptional repression of Plxnc1 by Lmx1a and Lmx1b directs topographic dopaminergic circuit formation.Transcriptomic profiling of the ventral tegmental area and nucleus accumbens in rhesus macaques following long-term cocaine self-administration.Synergistic co-regulation and competition by a SOX9-GLI-FOXA phasic transcriptional network coordinate chondrocyte differentiation transitions.Targeting of NAT10 enhances healthspan in a mouse model of human accelerated aging syndrome.
P2860
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P2860
Genome-wide characterization of Foxa2 targets reveals upregulation of floor plate genes and repression of ventrolateral genes in midbrain dopaminergic progenitors
description
2012 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2012
@ast
im Juli 2012 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2012/07/01)
@sk
vědecký článek publikovaný v roce 2012
@cs
wetenschappelijk artikel (gepubliceerd op 2012/07/01)
@nl
наукова стаття, опублікована в липні 2012
@uk
مقالة علمية نشرت في يوليو 2012 حول موضوع: دماغ
@ar
name
Genome-wide characterization o ...... brain dopaminergic progenitors
@ast
Genome-wide characterization o ...... brain dopaminergic progenitors
@en
Genome-wide characterization o ...... brain dopaminergic progenitors
@nl
type
label
Genome-wide characterization o ...... brain dopaminergic progenitors
@ast
Genome-wide characterization o ...... brain dopaminergic progenitors
@en
Genome-wide characterization o ...... brain dopaminergic progenitors
@nl
prefLabel
Genome-wide characterization o ...... brain dopaminergic progenitors
@ast
Genome-wide characterization o ...... brain dopaminergic progenitors
@en
Genome-wide characterization o ...... brain dopaminergic progenitors
@nl
P2093
P2860
P50
P921
P356
P1433
P1476
Genome-wide characterization o ...... brain dopaminergic progenitors
@en
P2093
Emmanouil Metzakopian
Jeffrey A. Whitsett
Mali Salmon-Divon
Siew-Lan Ang
Thomas Perlmann
P2860
P304
P356
10.1242/DEV.081034
P407
P577
2012-07-01T00:00:00Z