Absence of post-translational aspartyl beta-hydroxylation of epidermal growth factor domains in mice leads to developmental defects and an increased incidence of intestinal neoplasia
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Evolution of distinct EGF domains with specific functionsVitamin C: update on physiology and pharmacologyCollagen and calcium-binding EGF domains 1 is frequently inactivated in ovarian cancer by aberrant promoter hypermethylation and modulates cell migration and survivalAsparagine beta-hydroxylation stabilizes the ankyrin repeat domain foldMutations in ASPH cause facial dysmorphism, lens dislocation, anterior-segment abnormalities, and spontaneous filtering blebs, or Traboulsi syndromeExpanding chemical biology of 2-oxoglutarate oxygenasesN-glycosylation of CD97 within the EGF domains is crucial for epitope accessibility in normal and malignant cells as well as CD55 ligand bindingExpression of aspartyl beta-hydroxylase and its clinicopathological significance in hepatocellular carcinomaConsequences of IkappaB alpha hydroxylation by the factor inhibiting HIF (FIH)si-RNA inhibition of brain insulin or insulin-like growth factor receptors causes developmental cerebellar abnormalities: relevance to fetal alcohol spectrum disorder.Differential growth factor regulation of aspartyl-(asparaginyl)-beta-hydroxylase family genes in SH-Sy5y human neuroblastoma cells.Development of a novel anti-human aspartyl-(asparaginyl) β-hydroxylase monoclonal antibody with diagnostic and therapeutic potential.Motor Function Deficits Following Chronic Prenatal Ethanol Exposure are Linked to Impairments in Insulin/IGF, Notch and Wnt Signaling in the Cerebellum.Ethanol inhibition of aspartyl-asparaginyl-beta-hydroxylase in fetal alcohol spectrum disorder: potential link to the impairments in central nervous system neuronal migration.Glycosylation regulates Notch signalling.Role of aspartyl-(asparaginyl)-β-hydroxylase mediated notch signaling in cerebellar development and function.Glial vascular degeneration in CADASIL.Protein Hydroxylation Catalyzed by 2-Oxoglutarate-dependent Oxygenases.Aspartyl-(asparaginyl) beta-hydroxylase, hypoxia-inducible factor-alpha and Notch cross-talk in regulating neuronal motilityImmunization with aspartate-β-hydroxylase-loaded dendritic cells produces antitumor effects in a rat model of intrahepatic cholangiocarcinoma.Anti-Tumor Effects of Second Generation β-Hydroxylase Inhibitors on Cholangiocarcinoma Development and Progression.Ceramide inhibitor myriocin restores insulin/insulin growth factor signaling for liver remodeling in experimental alcohol-related steatohepatitis.Activation of dioxin response element (DRE)-associated genes by benzo(a)pyrene 3,6-quinone and benzo(a)pyrene 1,6-quinone in MCF-10A human mammary epithelial cells.Binding of calcium to anticoagulant protein S: role of the fourth EGF moduleOptimized Expression and Purification of Humbug in Pichia pastoris and Its Monoclonal Antibody Preparation.Systems genetics implicates cytoskeletal genes in oocyte control of cloned embryo quality.Regulatory roles of junctin in sarcoplasmic reticulum calcium cycling and myocardial function.siRNA inhibition of aspartyl-asparaginyl β-hydroxylase expression impairs cell motility, Notch signaling, and fetal growth.APC and its modifiers in colon cancer.Role of isocitrate dehydrogenase in glioma.Oncometabolites-driven tumorigenesis: From genetics to targeted therapy.Global Membrane Protein Interactome Analysis using In vivo Crosslinking and Mass Spectrometry-based Protein Correlation Profiling.A Radiolabeled Fully Human Antibody to Human Aspartyl (Asparaginyl) β-Hydroxylase Is a Promising Agent for Imaging and Therapy of Metastatic Breast Cancer.Overexpression of aspartyl-(asparaginyl)-beta-hydroxylase in hepatocellular carcinoma is associated with worse surgical outcome.Phosphorylation Modulates Aspartyl-(Asparaginyl)-β Hydroxylase Protein Expression, Catalytic Activity and Migration in Human Immature Neuronal Cerebellar Cells.Calcium-Binding EGF-Like DomainsTargeting the Cellular “Oxygen Sensors”: Hypoxia Pre-Conditioning and Stabilization of Hypoxia-Inducible Factors
P2860
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P2860
Absence of post-translational aspartyl beta-hydroxylation of epidermal growth factor domains in mice leads to developmental defects and an increased incidence of intestinal neoplasia
description
2002 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
artículu científicu espublizáu en 2002
@ast
im April 2002 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2002/04/12)
@sk
vědecký článek publikovaný v roce 2002
@cs
wetenschappelijk artikel (gepubliceerd op 2002/04/12)
@nl
наукова стаття, опублікована у квітні 2002
@uk
name
Absence of post-translational ...... idence of intestinal neoplasia
@ast
Absence of post-translational ...... idence of intestinal neoplasia
@en
Absence of post-translational ...... idence of intestinal neoplasia
@nl
type
label
Absence of post-translational ...... idence of intestinal neoplasia
@ast
Absence of post-translational ...... idence of intestinal neoplasia
@en
Absence of post-translational ...... idence of intestinal neoplasia
@nl
prefLabel
Absence of post-translational ...... idence of intestinal neoplasia
@ast
Absence of post-translational ...... idence of intestinal neoplasia
@en
Absence of post-translational ...... idence of intestinal neoplasia
@nl
P2093
P2860
P3181
P356
P1476
Absence of post-translational ...... idence of intestinal neoplasia
@en
P2093
Andrew A. Stern
Bernard H. Selling
Gregory F. Hollis
Jennifer A. Kelley
Jianhong Ma
Joseph E. Dinchuk
Mark J. Rupar
Mark R. Cunningham
Nancy L. Henderson
P2860
P304
12970–12977
P3181
P356
10.1074/JBC.M110389200
P407
P577
2002-04-12T00:00:00Z