Osteoclast stimulatory transmembrane protein (OC-STAMP), a novel protein induced by RANKL that promotes osteoclast differentiation
about
Tks5-dependent formation of circumferential podosomes/invadopodia mediates cell-cell fusionRegulation of osteoclasts by membrane-derived lipid mediatorsStudies of OC-STAMP in Osteoclast Fusion: A New Knockout Mouse Model, Rescue of Cell Fusion, and Transmembrane TopologyDC-STAMP: A Key Regulator in Osteoclast DifferentiationCD109 plays a role in osteoclastogenesisMolecules and signaling pathways involved in the expression of OC-STAMP during osteoclastogenesisGenetic basis of cell-cell fusion mechanisms.RANKL induces heterogeneous DC-STAMP(lo) and DC-STAMP(hi) osteoclast precursors of which the DC-STAMP(lo) precursors are the master fusogens.SNX10 gene mutation leading to osteopetrosis with dysfunctional osteoclasts.Using osteoclast differentiation as a model for gene discovery in an undergraduate cell biology laboratory.Recent advances in understanding the mechanisms of osteoclast precursor fusion.The loss of Cbl-phosphatidylinositol 3-kinase interaction perturbs RANKL-mediated signaling, inhibiting bone resorption and promoting osteoclast survival.Dynamin and endocytosis are required for the fusion of osteoclasts and myoblasts.Dual Effect of Chrysanthemum indicum Extract to Stimulate Osteoblast Differentiation and Inhibit Osteoclast Formation and Resorption In VitroAgelasine D suppresses RANKL-induced osteoclastogenesis via down-regulation of c-Fos, NFATc1 and NF-κB.(+)-Vitisin A inhibits osteoclast differentiation by preventing TRAF6 ubiquitination and TRAF6-TAK1 formation to suppress NFATc1 activationSexual Dimorphism in MAPK-Activated Protein Kinase-2 (MK2) Regulation of RANKL-Induced Osteoclastogenesis in Osteoclast Progenitor Subpopulations.RNA therapeutics targeting osteoclast-mediated excessive bone resorption.Serum amyloid A inhibits RANKL-induced osteoclast formation.Osteoclast fusion and regulation by RANKL-dependent and independent factors.Microgravity Induction of TRAIL Expression in Preosteoclast Cells Enhances Osteoclast Differentiation.Muscle Paralysis Induces Bone Marrow Inflammation and Predisposition to Formation of Giant Osteoclasts.Selective targeting of Bromodomains of the Bromodomain-PHD Fingers family impairs osteoclast differentiation.DC-STAMP Is an Osteoclast Fusogen Engaged in Periodontal Bone Resorption.Possible role of IRTKS in Tks5-driven osteoclast fusion.Osteoclastogenesis is influenced by modulation of gap junctional communication with antiarrhythmic peptides.Foreign body giant cells and osteoclasts are TRAP positive, have podosome-belts and both require OC-STAMP for cell fusion.Mevalonates restore zoledronic acid-induced osteoclastogenesis inhibition.FAM19A5, a brain-specific chemokine, inhibits RANKL-induced osteoclast formation through formyl peptide receptor 2.Atorvastatin inhibits osteoclast differentiation by suppressing NF-κB and MAPK signaling during IL-1β-induced osteoclastogenesis.Osteoclast stimulatory transmembrane protein induces a phenotypic switch in macrophage polarization suppressing an M1 pro-inflammatory state.Lysophosphatidic acid stimulates osteoclast fusion through OC-STAMP and P2X7 receptor signaling.Conditional Disruption of miR17~92 in Osteoclasts Led to Activation of Osteoclasts and Loss of Trabecular Bone In Part Through Suppression of the miR17-Mediated Downregulation of Protein-Tyrosine Phosphatase-oc in Mice.Vitamin E decreases bone mass by stimulating osteoclast fusion.Genetic backgrounds and redox conditions influence morphological characteristics and cell differentiation of osteoclasts in mice.
P2860
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P2860
Osteoclast stimulatory transmembrane protein (OC-STAMP), a novel protein induced by RANKL that promotes osteoclast differentiation
description
2008 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի մայիսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2008
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im Mai 2008 veröffentlichter wissenschaftlicher Artikel
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scientific journal article
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vedecký článok (publikovaný 2008/05/01)
@sk
vědecký článek publikovaný v roce 2008
@cs
wetenschappelijk artikel (gepubliceerd op 2008/05/01)
@nl
наукова стаття, опублікована в травні 2008
@uk
مقالة علمية (نشرت في مايو 2008)
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name
Osteoclast stimulatory transme ...... tes osteoclast differentiation
@ast
Osteoclast stimulatory transme ...... tes osteoclast differentiation
@en
Osteoclast stimulatory transme ...... tes osteoclast differentiation
@nl
type
label
Osteoclast stimulatory transme ...... tes osteoclast differentiation
@ast
Osteoclast stimulatory transme ...... tes osteoclast differentiation
@en
Osteoclast stimulatory transme ...... tes osteoclast differentiation
@nl
prefLabel
Osteoclast stimulatory transme ...... tes osteoclast differentiation
@ast
Osteoclast stimulatory transme ...... tes osteoclast differentiation
@en
Osteoclast stimulatory transme ...... tes osteoclast differentiation
@nl
P2093
P2860
P3181
P356
P1476
Osteoclast stimulatory transme ...... tes osteoclast differentiation
@en
P2093
April Mason-Savas
Benjamin Thompson
Carole A. MacKay
Mark J. Birnbaum
Meiheng Yang
Paul R. Odgren
P2860
P304
P3181
P356
10.1002/JCP.21331
P577
2008-05-01T00:00:00Z