Neuronal Shp2 tyrosine phosphatase controls energy balance and metabolism
about
Diversity and functional consequences of germline and somatic PTPN11 mutations in human disease.Ptpn11/Shp2 acts as a tumor suppressor in hepatocellular carcinogenesisRecent advances in understanding leptin signaling and leptin resistanceRole of Protein Phosphorylation and Tyrosine Phosphatases in the Adrenal Regulation of Steroid Synthesis and Mitochondrial FunctionControl of metabolic and cardiovascular function by the leptin-brain melanocortin pathwayLeptin's role in lipodystrophic and nonlipodystrophic insulin-resistant and diabetic individualsLeptin signaling and leptin resistanceAcute leptin treatment enhances functional recovery after spinal cord injuryCoordinated regulation by Shp2 tyrosine phosphatase of signaling events controlling insulin biosynthesis in pancreatic beta-cellsProtein tyrosine phosphatases in the JAK/STAT pathwayShp2 in forebrain neurons regulates synaptic plasticity, locomotion, and memory formation in miceSHP-1 and SHP-2 in T cells: two phosphatases functioning at many levelsAcute effects of leptin require PI3K signaling in hypothalamic proopiomelanocortin neurons in mice.Novel role for SHP-2 in nutrient-responsive control of S6 kinase 1 signaling.Postnatal growth after intrauterine growth restriction alters central leptin signal and energy homeostasis.A conserved mechanism for control of human and mouse embryonic stem cell pluripotency and differentiation by shp2 tyrosine phosphatase.Frs2α and Shp2 signal independently of Gab to mediate FGF signaling in lens development.Control of oligodendrocyte generation and proliferation by Shp2 protein tyrosine phosphatase.Deletion of Shp2 in bronchial epithelial cells impairs IL-25 production in vitro, but has minor influence on asthmatic inflammation in vivo.PTP1B and SHP2 in POMC neurons reciprocally regulate energy balance in mice.Sprouty2-modulated Kras signaling rescues Shp2 deficiency during lens and lacrimal gland development.Signaling through Tyr985 of leptin receptor as an age/diet-dependent switch in the regulation of energy balanceTemporal requirement of the protein tyrosine phosphatase Shp2 in establishing the neuronal fate in early retinal development.Helicobacter pylori CagA phosphorylation status determines the gp130-activated SHP2/ERK and JAK/STAT signal transduction pathways in gastric epithelial cells.Metabolic regulation by protein tyrosine phosphatases.Twin infant with lymphatic dysplasia diagnosed with Noonan syndrome by molecular genetic testingObesity-induced hypertension: role of sympathetic nervous system, leptin, and melanocortinsA role of phosphodiesterase-3B pathway in mediating leptin action on proopiomelanocortin and neurotensin neurons in the hypothalamus.Inactivation of SOCS3 in leptin receptor-expressing cells protects mice from diet-induced insulin resistance but does not prevent obesityGlucose enhances leptin signaling through modulation of AMPK activity.Leptin signaling.20 years of leptin: connecting leptin signaling to biological functionEnhanced leptin sensitivity, reduced adiposity, and improved glucose homeostasis in mice lacking exchange protein directly activated by cyclic AMP isoform 1LEOPARD syndrome-associated SHP2 mutation confers leanness and protection from diet-induced obesityDevelopment of severe skeletal defects in induced SHP-2-deficient adult mice: a model of skeletal malformation in humans with SHP-2 mutationsMEK-ERK pathway modulation ameliorates disease phenotypes in a mouse model of Noonan syndrome associated with the Raf1(L613V) mutationShp2 signaling in POMC neurons is important for leptin's actions on blood pressure, energy balance, and glucose regulationProtein tyrosine phosphatase-1B contributes to LPS-induced leptin resistance in male ratsProtein-tyrosine phosphatase Shp2 positively regulates macrophage oxidative burstTyrosine phosphatases epsilon and alpha perform specific and overlapping functions in regulation of voltage-gated potassium channels in Schwann cells.
P2860
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P2860
Neuronal Shp2 tyrosine phosphatase controls energy balance and metabolism
description
2004 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
article publié dans les Procee ...... f the United States of America
@fr
artículu científicu espublizáu en 2004
@ast
im November 2004 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2004/11/09)
@sk
vědecký článek publikovaný v roce 2004
@cs
wetenschappelijk artikel (gepubliceerd op 2004/11/09)
@nl
наукова стаття, опублікована в листопаді 2004
@uk
name
Neuronal Shp2 tyrosine phosphatase controls energy balance and metabolism
@ast
Neuronal Shp2 tyrosine phosphatase controls energy balance and metabolism
@en
Neuronal Shp2 tyrosine phosphatase controls energy balance and metabolism
@nl
type
label
Neuronal Shp2 tyrosine phosphatase controls energy balance and metabolism
@ast
Neuronal Shp2 tyrosine phosphatase controls energy balance and metabolism
@en
Neuronal Shp2 tyrosine phosphatase controls energy balance and metabolism
@nl
prefLabel
Neuronal Shp2 tyrosine phosphatase controls energy balance and metabolism
@ast
Neuronal Shp2 tyrosine phosphatase controls energy balance and metabolism
@en
Neuronal Shp2 tyrosine phosphatase controls energy balance and metabolism
@nl
P2093
P2860
P3181
P356
P1476
Neuronal Shp2 tyrosine phosphatase controls energy balance and metabolism
@en
P2093
Emilie Chapeau
Gen-Sheng Feng
Kazuki Hagihara
P2860
P304
16064-16069
P3181
P356
10.1073/PNAS.0405041101
P407
P577
2004-11-01T00:00:00Z