Lack of cadherins Celsr2 and Celsr3 impairs ependymal ciliogenesis, leading to fatal hydrocephalus
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The Small GTPase Rsg1 is important for the cytoplasmic localization and axonemal dynamics of intraflagellar transport proteinsVisualisation of cerebrospinal fluid flow patterns in albino Xenopus larvae in vivoICK is essential for cell type-specific ciliogenesis and the regulation of ciliary transportFrizzled3 is required for the development of multiple axon tracts in the mouse central nervous systemThe cell biology of planar cell polarityUnderstanding ciliated epithelia: the power of XenopusAlix-mediated assembly of the actomyosin-tight junction polarity complex preserves epithelial polarity and epithelial barrierThe PDZ Protein Na+/H+ Exchanger Regulatory Factor-1 (NHERF1) Regulates Planar Cell Polarity and Motile Cilia OrganizationGpr116 Receptor Regulates Distinctive Functions in Pneumocytes and Vascular EndotheliumEctopic expression of human BBS4 can rescue Bardet-Biedl syndrome phenotypes in Bbs4 null miceSperm-associated antigen 6 (SPAG6) deficiency and defects in ciliogenesis and cilia function: polarity, density, and beatSortilin, encoded by the cardiovascular risk gene SORT1, and its suggested functions in cardiovascular diseaseInternational Union of Basic and Clinical Pharmacology. XCIV. Adhesion G protein-coupled receptorsActivation of myeloid cell-specific adhesion class G protein-coupled receptor EMR2 via ligation-induced translocation and interaction of receptor subunits in lipid raft microdomainsPTEN regulates cilia through Dishevelled.Sticky signaling--adhesion class G protein-coupled receptors take the stageGpr97 is essential for the follicular versus marginal zone B-lymphocyte fate decisionArl13b-regulated cilia activities are essential for polarized radial glial scaffold formationPlanar cell polarity effector gene Intu regulates cell fate-specific differentiation of keratinocytes through the primary ciliaAbnormal development of NG2+PDGFR-α+ neural progenitor cells leads to neonatal hydrocephalus in a ciliopathy mouse modelCiliary proteins Bbs8 and Ift20 promote planar cell polarity in the cochleaComparative expression study of the endo-G protein coupled receptor (GPCR) repertoire in human glioblastoma cancer stem-like cells, U87-MG cells and non malignant cells of neural origin unveils new potential therapeutic targetsDisruption of the mouse Jhy gene causes abnormal ciliary microtubule patterning and juvenile hydrocephalusTubulin glycylases and glutamylases have distinct functions in stabilization and motility of ependymal ciliaKnockdown of Bardet-Biedl syndrome gene BBS9/PTHB1 leads to cilia defectsAtypical cadherins Celsr1-3 differentially regulate migration of facial branchiomotor neurons in miceFrom Planar Cell Polarity to Ciliogenesis and Back: The Curious Tale of the PPE and CPLANE proteins.Mechanical strain determines the axis of planar polarity in ciliated epitheliaProteomic analysis of multiple primary cilia reveals a novel mode of ciliary development in mammalsLysophosphatidic acid signaling may initiate fetal hydrocephalus.Transcription factor Emx2 controls stereociliary bundle orientation of sensory hair cells.Loss of Mpdz impairs ependymal cell integrity leading to perinatal-onset hydrocephalus in mice.Genetic evidence that Celsr3 and Celsr2, together with Fzd3, regulate forebrain wiring in a Vangl-independent mannerStructural and temporal requirements of Wnt/PCP protein Vangl2 function for convergence and extension movements and facial branchiomotor neuron migration in zebrafishA dual role for planar cell polarity genes in ciliated cellsLoss of Dishevelleds disrupts planar polarity in ependymal motile cilia and results in hydrocephalus.Traumatic brain injury-induced ependymal ciliary loss decreases cerebral spinal fluid flow.Cilia in the CNS: the quiet organelle claims center stageNull and hypomorph Prickle1 alleles in mice phenocopy human Robinow syndrome and disrupt signaling downstream of Wnt5aRegulation of the protocadherin Celsr3 gene and its role in globus pallidus development and connectivity.
P2860
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P248
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P2860
Lack of cadherins Celsr2 and Celsr3 impairs ependymal ciliogenesis, leading to fatal hydrocephalus
description
2010 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հունիսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2010
@ast
im Juni 2010 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2010/06/01)
@sk
vědecký článek publikovaný v roce 2010
@cs
wetenschappelijk artikel (gepubliceerd op 2010/06/01)
@nl
наукова стаття, опублікована в червні 2010
@uk
مقالة علمية (نشرت في يونيو 2010)
@ar
name
Lack of cadherins Celsr2 and C ...... leading to fatal hydrocephalus
@ast
Lack of cadherins Celsr2 and C ...... leading to fatal hydrocephalus
@en
Lack of cadherins Celsr2 and C ...... leading to fatal hydrocephalus
@nl
type
label
Lack of cadherins Celsr2 and C ...... leading to fatal hydrocephalus
@ast
Lack of cadherins Celsr2 and C ...... leading to fatal hydrocephalus
@en
Lack of cadherins Celsr2 and C ...... leading to fatal hydrocephalus
@nl
prefLabel
Lack of cadherins Celsr2 and C ...... leading to fatal hydrocephalus
@ast
Lack of cadherins Celsr2 and C ...... leading to fatal hydrocephalus
@en
Lack of cadherins Celsr2 and C ...... leading to fatal hydrocephalus
@nl
P2093
P50
P921
P3181
P356
P1433
P1476
Lack of cadherins Celsr2 and C ...... leading to fatal hydrocephalus
@en
P2093
Andre M. Goffinet
Fadel Tissir
Jason Labeau
Kouji Komatsu
Libing Zhou
Pierre Courtoy
P2888
P304
P3181
P356
10.1038/NN.2555
P407
P577
2010-06-01T00:00:00Z
P5875
P6179
1000648912