Dysfunctional mammalian telomeres join with DNA double-strand breaks
about
The DNA-dependent protein kinase: A multifunctional protein kinase with roles in DNA double strand break repair and mitosisThe role of NBS1 in DNA double strand break repair, telomere stability, and cell cycle checkpoint controlTargeting human telomeric G-quadruplex DNA and inhibition of telomerase activity with [(dmb)2Ru(obip)Ru(dmb)2](4+)An increase in telomere sister chromatid exchange in murine embryonic stem cells possessing critically shortened telomeres.Mice with bad ends: mouse models for the study of telomeres and telomerase in cancer and aging.Regulatory roles of tankyrase 1 at telomeres and in DNA repair: suppression of T-SCE and stabilization of DNA-PKcs.DNA repair kinetics in SCID mice Sertoli cells and DNA-PKcs-deficient mouse embryonic fibroblasts.Telomere fusion to chromosome breaks reduces oncogenic translocations and tumour formation.Telomeres, chromosome instability and cancerMurine Prkdc polymorphisms impact DNA-PKcs functionCentromere fission, not telomere erosion, triggers chromosomal instability in human carcinomas.Ectopic TLX1 expression accelerates malignancies in mice deficient in DNA-PK.53BP1 mediates the fusion of mammalian telomeres rendered dysfunctional by DNA-PKcs loss or inhibition.Identification of telomere dysfunction in Friedreich ataxiaThe life and death of DNA-PK.Telomeres and Telomerase in the Radiation Response: Implications for Instability, Reprograming, and Carcinogenesis.Impact of telomerase ablation on organismal viability, aging, and tumorigenesis in mice lacking the DNA repair proteins PARP-1, Ku86, or DNA-PKcsPARP1 and DNA-PKcs synergize to suppress p53 mutation and telomere fusions during T-lineage lymphomagenesis.Telomere dysfunction and DNA-PKcs deficiency: characterization and consequence.Molecular cytogenetics in the study of cutaneous T-cell lymphomas (CTCL).Tracking genomic instability within irradiated and bystander populations.Chromosomal aberrations involving telomeres and interstitial telomeric sequences.Emerging roles of SIRT6 on telomere maintenance, DNA repair, metabolism and mammalian aging.Genome organization, instabilities, stem cells, and cancer.From radioresistance to radiosensitivity: In vitro evolution of L5178Y lymphoma.Directional genomic hybridization for chromosomal inversion discovery and detection.Effects of BRCA2 deficiency on telomere recombination in non-ALT and ALT cells.Chromosomal aberrations involving telomeres in BRCA1 deficient human and mouse cell lines.Differential radiation effects in smokers--culture time dependence of the yield of gamma ray-induced chromosome damage in first division metaphases.Tumor Cell-Accelerated Senescence Is Associated With DNA-PKcs Status and Telomere Dysfunction Induced by Radiation.
P2860
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P2860
Dysfunctional mammalian telomeres join with DNA double-strand breaks
description
2004 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2004
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scientific journal article
@en
vedecký článok (publikovaný 2004/04/01)
@sk
vědecký článek publikovaný v roce 2004
@cs
wetenschappelijk artikel (gepubliceerd op 2004/04/01)
@nl
wissenschaftlicher Artikel
@de
наукова стаття, опублікована у квітні 2004
@uk
مقالة علمية (نشرت في أبريل 2004)
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name
Dysfunctional mammalian telomeres join with DNA double-strand breaks
@ast
Dysfunctional mammalian telomeres join with DNA double-strand breaks
@en
Dysfunctional mammalian telomeres join with DNA double-strand breaks
@nl
type
label
Dysfunctional mammalian telomeres join with DNA double-strand breaks
@ast
Dysfunctional mammalian telomeres join with DNA double-strand breaks
@en
Dysfunctional mammalian telomeres join with DNA double-strand breaks
@nl
prefLabel
Dysfunctional mammalian telomeres join with DNA double-strand breaks
@ast
Dysfunctional mammalian telomeres join with DNA double-strand breaks
@en
Dysfunctional mammalian telomeres join with DNA double-strand breaks
@nl
P2093
P1433
P1476
Dysfunctional mammalian telomeres join with DNA double-strand breaks
@en
P2093
Edwin H. Goodwin
Michael N. Cornforth
Robert L. Ullrich
Susan M. Bailey
P304
P356
10.1016/J.DNAREP.2003.11.007
P577
2004-04-01T00:00:00Z