Tumor necrosis factor receptor-associated factor 2 (TRAF2)-deficient B lymphocytes reveal novel roles for TRAF2 in CD40 signaling
about
TNAP, a novel repressor of NF-kappaB-inducing kinase, suppresses NF-kappaB activationSIGIRR inhibits interleukin-1 receptor- and toll-like receptor 4-mediated signaling through different mechanismsThe E3 ubiquitin ligase Triad3A negatively regulates the RIG-I/MAVS signaling pathway by targeting TRAF3 for degradationHOIL-1L interacting protein (HOIP) as an NF-kappaB regulating component of the CD40 signaling complexRoles of tumor necrosis factor receptor associated factor 3 (TRAF3) and TRAF5 in immune cell functionsEpstein-Barr virus LMP2A reduces hyperactivation induced by LMP1 to restore normal B cell phenotype in transgenic miceThe developmental regulator protein Gon4l associates with protein YY1, co-repressor Sin3a, and histone deacetylase 1 and mediates transcriptional repressionCDK-mediated regulation of cell functions via c-Jun phosphorylation and AP-1 activation.HOIL-1L interacting protein (HOIP) is essential for CD40 signalingThe noncanonical NF-κB pathway.cIAP1-dependent TRAF2 degradation regulates the differentiation of monocytes into macrophages and their response to CD40 ligandA BAFF-R mutation associated with non-Hodgkin lymphoma alters TRAF recruitment and reveals new insights into BAFF-R signaling.Emerging complexity of protein ubiquitination in the NF-κB pathway.The germinal center kinase TNIK is required for canonical NF-κB and JNK signaling in B-cells by the EBV oncoprotein LMP1 and the CD40 receptor.A new model of LMP1-MYC interaction in B cell lymphoma.Differential TRAF3 utilization by a variant human CD40 receptor with enhanced signalingA novel TNF receptor-associated factor 6 binding domain mediates NF-kappa B signaling by the common cytokine receptor beta subunit.Molecular mechanisms of TNFR-associated factor 6 (TRAF6) utilization by the oncogenic viral mimic of CD40, latent membrane protein 1 (LMP1).SUMOylation is required for optimal TRAF3 signaling capacityEnhanced Toll-like receptor (TLR) responses of TNFR-associated factor 3 (TRAF3)-deficient B lymphocytes.Targeting signaling factors for degradation, an emerging mechanism for TRAF functionsTRAF2: a double-edged sword?Requirement for TRAF3 in signaling by LMP1 but not CD40 in B lymphocytesTNFR-associated factor 2 deficiency in B lymphocytes predisposes to chronic lymphocytic leukemia/small lymphocytic lymphoma in mice.EBV LMP2A affects LMP1-mediated NF-kappaB signaling and survival of lymphoma cells by regulating TRAF2 expression.TRAF2 regulates TNF and NF-κB signalling to suppress apoptosis and skin inflammation independently of Sphingosine kinase 1Roles of TRAF molecules in B lymphocyte functionLymphocyte-specific TRAF3 transgenic mice have enhanced humoral responses and develop plasmacytosis, autoimmunity, inflammation, and cancerTRAF2 and TRAF3 independently mediate Ig class switching driven by CD40.TRAF5 is a critical mediator of in vitro signals and in vivo functions of LMP1, the viral oncogenic mimic of CD40.Molecular mechanism and function of CD40/CD40L engagement in the immune system.TIFA activates IkappaB kinase (IKK) by promoting oligomerization and ubiquitination of TRAF6.TRAF-mediated regulation of immune and inflammatory responses.Non-canonical NF-κB signaling pathway.How do pleiotropic kinase hubs mediate specific signaling by TNFR superfamily members?LTβR and CD40: working together in dendritic cells to optimize immune responses.Roles for TNF-receptor associated factor 3 (TRAF3) in lymphocyte functions.TRAF3, ubiquitination, and B-lymphocyte regulation.Induction of the alternative NF-κB pathway by lymphotoxin αβ (LTαβ) relies on internalization of LTβ receptor.TRAF6 is required for TRAF2-dependent CD40 signal transduction in nonhemopoietic cells
P2860
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P2860
Tumor necrosis factor receptor-associated factor 2 (TRAF2)-deficient B lymphocytes reveal novel roles for TRAF2 in CD40 signaling
description
2003 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
artículu científicu espublizáu en 2003
@ast
im November 2003 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2003/11/14)
@sk
vědecký článek publikovaný v roce 2003
@cs
wetenschappelijk artikel (gepubliceerd op 2003/11/14)
@nl
наукова стаття, опублікована в листопаді 2003
@uk
name
Tumor necrosis factor receptor ...... es for TRAF2 in CD40 signaling
@ast
Tumor necrosis factor receptor ...... es for TRAF2 in CD40 signaling
@en
Tumor necrosis factor receptor ...... es for TRAF2 in CD40 signaling
@nl
type
label
Tumor necrosis factor receptor ...... es for TRAF2 in CD40 signaling
@ast
Tumor necrosis factor receptor ...... es for TRAF2 in CD40 signaling
@en
Tumor necrosis factor receptor ...... es for TRAF2 in CD40 signaling
@nl
prefLabel
Tumor necrosis factor receptor ...... es for TRAF2 in CD40 signaling
@ast
Tumor necrosis factor receptor ...... es for TRAF2 in CD40 signaling
@en
Tumor necrosis factor receptor ...... es for TRAF2 in CD40 signaling
@nl
P2093
P2860
P921
P356
P1476
Tumor necrosis factor receptor ...... es for TRAF2 in CD40 signaling
@en
P2093
Bruce S. Hostager
Gail A. Bishop
Sarah L. Rowland
Sokol A. Haxhinasto
P2860
P304
45382–45390
P356
10.1074/JBC.M306708200
P407
P577
2003-11-14T00:00:00Z