The ETS protein MEF plays a critical role in perforin gene expression and the development of natural killer and NK-T cells
about
Myeloid ELF1-like factor is a potent activator of interleukin-8 expression in hematopoietic cellsMyeloid Elf-1-like factor, an ETS transcription factor, up-regulates lysozyme transcription in epithelial cells through interaction with promyelocytic leukemia proteinThe ETS protein MEF is regulated by phosphorylation-dependent proteolysis via the protein-ubiquitin ligase SCFSkp2.The transcription factor PLZF directs the effector program of the NKT cell lineageThe oncogenic role of the ETS transcription factors MEF and ERGRoles and regulations of the ETS transcription factor ELF4/MEFMature natural killer cell and lymphoid tissue-inducing cell development requires Id2-mediated suppression of E protein activityMouse Hobit is a homolog of the transcriptional repressor Blimp-1 that regulates NKT cell effector differentiationProgression of regulatory gene expression states in fetal and adult pro-T-cell development.Invariant NKT cell development requires a full complement of functional CD3 zeta immunoreceptor tyrosine-based activation motifsMEF up-regulates human beta-defensin 2 expression in epithelial cells.An effector phenotype of CD8+ T cells at the junction epithelium during clinical quiescence of herpes simplex virus 2 infection.Molecular mechanisms influencing NK cell development: implications for NK cell malignancies.Differential requirements for the Ets transcription factor Elf-1 in the development of NKT cells and NK cellsDiverse roles of inhibitor of differentiation 2 in adaptive immunity.Peripheral natural killer cell maturation depends on the transcription factor AiolosThe transcription factor E74-like factor controls quiescence of endothelial cells and their resistance to myeloablative treatments in bone marrow.The basic leucine zipper transcription factor E4BP4 is essential for natural killer cell development.Predicting tissue specific transcription factor binding sites.Innate self recognition by an invariant, rearranged T-cell receptor and its immune consequences.Inactivation of X-linked tumor suppressor genes in human cancer.Integration of Elf-4 into stem/progenitor and erythroid regulatory networks through locus-wide chromatin studies coupled with in vivo functional validationGenetic control of NKT cell numbers.Kruppel-like factor 4 (KLF4) promotes the survival of natural killer cells and maintains the number of conventional dendritic cells in the spleenPrimary hemophagocytic syndromes point to a direct link between lymphocyte cytotoxicity and homeostasis.Gene deregulation and chronic activation in natural killer cells deficient in the transcription factor ETS1TGF-β is responsible for NK cell immaturity during ontogeny and increased susceptibility to infection during mouse infancy.At the crossroads: diverse roles of early thymocyte transcriptional regulators.The transcriptional control of the perforin locusDevelopment and maturation of natural killer cellsMutations in the nucleolar phosphoprotein, nucleophosmin, promote the expression of the oncogenic transcription factor MEF/ELF4 in leukemia cells and potentiates transformation.Core binding factors are necessary for natural killer cell development and cooperate with Notch signaling during T-cell specificationDoes the developmental status of Valpha14i NKT cells play a role in disease?Ets transcription factors in intestinal morphogenesis, homeostasis and disease.The transcription factor E74-like factor 4 suppresses differentiation of proliferating CD4+ T cells to the Th17 lineageExpression profiles frame the promoter specificity dilemma of the ETS family of transcription factorsELF4 is critical for induction of type I interferon and the host antiviral response.Regulation of Murine Natural Killer Cell Development.Raising the NKT cell family.The transcription factor E4bp4/Nfil3 controls commitment to the NK lineage and directly regulates Eomes and Id2 expression.
P2860
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P2860
The ETS protein MEF plays a critical role in perforin gene expression and the development of natural killer and NK-T cells
description
2002 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2002
@ast
im Oktober 2002 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2002/10/01)
@sk
vědecký článek publikovaný v roce 2002
@cs
wetenschappelijk artikel (gepubliceerd op 2002/10/01)
@nl
наукова стаття, опублікована в жовтні 2002
@uk
مقالة علمية (نشرت في أكتوبر 2002)
@ar
name
The ETS protein MEF plays a cr ...... natural killer and NK-T cells
@ast
The ETS protein MEF plays a cr ...... natural killer and NK-T cells
@en
The ETS protein MEF plays a cr ...... natural killer and NK-T cells
@nl
type
label
The ETS protein MEF plays a cr ...... natural killer and NK-T cells
@ast
The ETS protein MEF plays a cr ...... natural killer and NK-T cells
@en
The ETS protein MEF plays a cr ...... natural killer and NK-T cells
@nl
prefLabel
The ETS protein MEF plays a cr ...... natural killer and NK-T cells
@ast
The ETS protein MEF plays a cr ...... natural killer and NK-T cells
@en
The ETS protein MEF plays a cr ...... natural killer and NK-T cells
@nl
P2093
P1433
P1476
The ETS protein MEF plays a cr ...... natural killer and NK-T cells
@en
P2093
Anthony Deblasio
Antonio Di Cristofano
Cyrus Hedvat
H. Daniel Lacorazza
Shifeng Mao
Stephen D. Nimer
Yasushi Miyazaki
P304
P356
10.1016/S1074-7613(02)00422-3
P407
P577
2002-10-01T00:00:00Z