Mutations in Sox18 underlie cardiovascular and hair follicle defects in ragged mice
about
Mutations in the transcription factor gene SOX18 underlie recessive and dominant forms of hypotrichosis-lymphedema-telangiectasiaThe transcription factor SOX18 regulates the expression of matrix metalloproteinase 7 and guidance molecules in human endothelial cellsControl of cell fate and differentiation by Sry-related high-mobility-group box (Sox) transcription factorsLymphatic fate specification: an ERK-controlled transcriptional programVascular anomalies: from genetics toward models for therapeutic trialsGenetics of lymphatic anomaliesThe VCAM-1 gene that encodes the vascular cell adhesion molecule is a target of the Sry-related high mobility group box gene, Sox18Vascular defects in a mouse model of hypotrichosis-lymphedema-telangiectasia syndrome indicate a role for SOX18 in blood vessel maturationMice null for sox18 are viable and display a mild coat defectMouse mu opioid receptor distal promoter transcriptional regulation by SOX proteinsSOX7 transcription factor: sequence, chromosomal localisation, expression, transactivation and interference with Wnt signallingA genotype-first approach for the molecular and clinical characterization of uncommon de novo microdeletion of 20q13.33Dkk4 and Eda regulate distinctive developmental mechanisms for subtypes of mouse hair.The nuclear hormone receptor Coup-TFII is required for the initiation and early maintenance of Prox1 expression in lymphatic endothelial cells.Sox18 preserves the pulmonary endothelial barrier under conditions of increased shear stress.The lymphatic system in health and disease.Sox7 is regulated by ETV2 during cardiovascular developmentCurrent views on the function of the lymphatic vasculature in health and diseaseEpidermal patterning and induction of different hair types during mouse embryonic development.Cytoplasmic plaque formation in hemidesmosome development is dependent on SoxF transcription factor functionTranscriptional control of endothelial cell development.Sox2-positive dermal papilla cells specify hair follicle type in mammalian epidermisTranscriptome sequencing reveals differences between primary and secondary hair follicle-derived dermal papilla cells of the Cashmere goat (Capra hircus).casanova encodes a novel Sox-related protein necessary and sufficient for early endoderm formation in zebrafishSox factors transcriptionally regulate ROBO4 gene expression in developing vasculature in zebrafish.Modulating hair follicle size with Wnt10b/DKK1 during hair regeneration.Expression of stanniocalcin 1 in thyroid side population cells and thyroid cancer cellsTrps1 activates a network of secreted Wnt inhibitors and transcription factors crucial to vibrissa follicle morphogenesis.Shh is required for Tabby hair follicle development.Sry-type HMG box 18 contributes to the differentiation of bone marrow-derived mesenchymal stem cells to endothelial cells.Sox7, Sox17, and Sox18 Cooperatively Regulate Vascular Development in the Mouse Retina.Abnormal pigmentation in hypomelanosis of Ito and pigmentary mosaicism: the role of pigmentary genes.Genetics of dark skin in mice.Molecular regulation of lymphangiogenesis in development and tumor microenvironment.Cutaneous retinoic acid levels determine hair follicle development and downgrowth.Mouse Sox17 haploinsufficiency leads to female subfertility due to impaired implantation.Structure and decoy-mediated inhibition of the SOX18/Prox1-DNA interactionBiomarkers of lymphatic function and disease: state of the art and future directions.From germline towards somatic mutations in the pathophysiology of vascular anomalies.Lymphatic endothelial differentiation: start out with Sox--carry on with Prox.
P2860
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P2860
Mutations in Sox18 underlie cardiovascular and hair follicle defects in ragged mice
description
2000 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
articolo scientifico
@it
artículu científicu espublizáu en 2000
@ast
im April 2000 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2000/04/01)
@sk
vědecký článek publikovaný v roce 2000
@cs
wetenschappelijk artikel (gepubliceerd op 2000/04/01)
@nl
наукова стаття, опублікована у квітні 2000
@uk
name
Mutations in Sox18 underlie cardiovascular and hair follicle defects in ragged mice
@ast
Mutations in Sox18 underlie cardiovascular and hair follicle defects in ragged mice
@en
Mutations in Sox18 underlie cardiovascular and hair follicle defects in ragged mice
@nl
type
label
Mutations in Sox18 underlie cardiovascular and hair follicle defects in ragged mice
@ast
Mutations in Sox18 underlie cardiovascular and hair follicle defects in ragged mice
@en
Mutations in Sox18 underlie cardiovascular and hair follicle defects in ragged mice
@nl
prefLabel
Mutations in Sox18 underlie cardiovascular and hair follicle defects in ragged mice
@ast
Mutations in Sox18 underlie cardiovascular and hair follicle defects in ragged mice
@en
Mutations in Sox18 underlie cardiovascular and hair follicle defects in ragged mice
@nl
P2093
P50
P3181
P356
P1433
P1476
Mutations in Sox18 underlie cardiovascular and hair follicle defects in ragged mice
@en
P2093
B. Hosking
D. Chambers
P2888
P304
P3181
P356
10.1038/74301
P407
P577
2000-04-01T00:00:00Z