Urea-selective concentrating defect in transgenic mice lacking urea transporter UT-B
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Regulation of renal urea transport by vasopressinMolecular mechanisms of urea transport in health and diseaseComparative physiology and architecture associated with the mammalian urine concentrating mechanism: role of inner medullary water and urea transport pathways in the rodent medullaDroplet-based microfluidic platform for measurement of rapid erythrocyte water transportStructure and permeation mechanism of a mammalian urea transporter.Perspectives on edema in childhood nephrotic syndromeProtein- and diabetes-induced glomerular hyperfiltration: role of glucagon, vasopressin, and ureaExpression of urea transporters in potassium-depleted mouse kidneyAnalysis of double knockout mice lacking aquaporin-1 and urea transporter UT-B. Evidence for UT-B-facilitated water transport in erythrocytesUrea and urine concentrating ability in mice lacking AQP1 and AQP3A genome-wide association study of bladder cancer identifies a new susceptibility locus within SLC14A1, a urea transporter gene on chromosome 18q12.3Emerging Targets of Diuretic Therapy.Detection of transgene expression using hyperpolarized 13C urea and diffusion-weighted magnetic resonance spectroscopy.Developing hypothetical inhibition mechanism of novel urea transporter B inhibitor.Generation and phenotypic analysis of mice lacking all urea transporters.Phosphorylation of UT-A1 on serine 486 correlates with membrane accumulation and urea transport activity in both rat IMCDs and cultured cellsFunctional implications of the three-dimensional architecture of the rat renal inner medulla.Urinary concentrating defect in mice with selective deletion of phloretin-sensitive urea transporters in the renal collecting ductImpaired urea accumulation in the inner medulla of mice lacking the urea transporter UT-A2.Diuresis and reduced urinary osmolality in rats produced by small-molecule UT-A-selective urea transport inhibitors.UT-B-deficient mice develop renal dysfunction and structural damage.Urea transport in the kidney.Adenylate cyclase 6 determines cAMP formation and aquaporin-2 phosphorylation and trafficking in inner medulla.UT-A urea transporter promoter, UT-Aalpha, targets principal cells of the renal inner medullary collecting duct.1,1-Difluoroethyl-substituted triazolothienopyrimidines as inhibitors of a human urea transport protein (UT-B): new analogs and binding modelThienoquinolins exert diuresis by strongly inhibiting UT-A urea transporters.A small molecule screen identifies selective inhibitors of urea transporter UT-A.Small-molecule inhibitors of urea transporters.Urea transporter UT-B deletion induces DNA damage and apoptosis in mouse bladder urotheliumCountercurrent exchange in the renal medulla.Structure-activity analysis of thiourea analogs as inhibitors of UT-A and UT-B urea transporters.European genome-wide association study identifies SLC14A1 as a new urinary bladder cancer susceptibility gene.High salt-diet reduces SLC14A1 gene expression in the choroid plexus of Dahl salt sensitive ratsRole of thin descending limb urea transport in renal urea handling and the urine concentrating mechanism.The emerging physiological roles of the SLC14A family of urea transporters.Discovery, synthesis and structure-activity analysis of symmetrical 2,7-disubstituted fluorenones as urea transporter inhibitors.Salt-sparing diuretic action of a water-soluble urea analog inhibitor of urea transporters UT-A and UT-B in ratsUrea and Ammonia Metabolism and the Control of Renal Nitrogen Excretion.Triazolothienopyrimidine inhibitors of urea transporter UT-B reduce urine concentration.Urea transporter physiology studied in knockout mice.
P2860
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P2860
Urea-selective concentrating defect in transgenic mice lacking urea transporter UT-B
description
2002 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի մարտին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
artículu científicu espublizáu en 2002
@ast
im März 2002 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2002/03/22)
@sk
vědecký článek publikovaný v roce 2002
@cs
wetenschappelijk artikel (gepubliceerd op 2002/03/22)
@nl
наукова стаття, опублікована в березні 2002
@uk
name
Urea-selective concentrating defect in transgenic mice lacking urea transporter UT-B
@ast
Urea-selective concentrating defect in transgenic mice lacking urea transporter UT-B
@en
Urea-selective concentrating defect in transgenic mice lacking urea transporter UT-B
@nl
type
label
Urea-selective concentrating defect in transgenic mice lacking urea transporter UT-B
@ast
Urea-selective concentrating defect in transgenic mice lacking urea transporter UT-B
@en
Urea-selective concentrating defect in transgenic mice lacking urea transporter UT-B
@nl
prefLabel
Urea-selective concentrating defect in transgenic mice lacking urea transporter UT-B
@ast
Urea-selective concentrating defect in transgenic mice lacking urea transporter UT-B
@en
Urea-selective concentrating defect in transgenic mice lacking urea transporter UT-B
@nl
P2093
P3181
P356
P1476
Urea-selective concentrating defect in transgenic mice lacking urea transporter UT-B
@en
P2093
A. S. Verkman
Annemarie Gillespie
Baoxue Yang
Charles J. Epstein
Lise Bankir
P304
10633–10637
P3181
P356
10.1074/JBC.M200207200
P407
P577
2002-03-22T00:00:00Z