A model organism approach: defining the role of Neph proteins as regulators of neuron and kidney morphogenesis
about
Motor protein Myo1c is a podocyte protein that facilitates the transport of slit diaphragm protein Neph1 to the podocyte membraneFunctional and spatial analysis of C. elegans SYG-1 and SYG-2, orthologs of the Neph/nephrin cell adhesion module directing selective synaptogenesisExtracellular Architecture of the SYG-1/SYG-2 Adhesion Complex Instructs SynaptogenesisComparative analysis of Neph gene expression in mouse and chicken developmentGenetic association for renal traits among participants of African ancestry reveals new loci for renal function.Structural Analysis of the Myo1c and Neph1 Complex Provides Insight into the Intracellular Movement of Neph1Using zebrafish to study podocyte genesis during kidney development and regeneration.Functional study of mammalian Neph proteins in Drosophila melanogasterIdentification of novel Kirrel3 gene splice variants in adult human skeletal muscle.A functional variant in NEPH3 gene confers high risk of renal failure in primary hematuric glomerulopathies. Evidence for predisposition to microalbuminuria in the general population.Human Induced Pluripotent Stem Cell-Derived Podocytes Mature into Vascularized Glomeruli upon Experimental TransplantationIdentification and characterization of novel Kirrel isoform during myogenesis.Myo1c is an unconventional myosin required for zebrafish glomerular development.Nephrin and Podocin functions are highly conserved between the zebrafish pronephros and mammalian metanephros.Slit diaphragm protein Neph1 and its signaling: a novel therapeutic target for protection of podocytes against glomerular injurySignaling from the podocyte intercellular junction to the actin cytoskeleton.Molecular understanding of the slit diaphragm.The podocyte slit diaphragm--from a thin grey line to a complex signalling hub.Functions of the podocyte proteins nephrin and Neph3 and the transcriptional regulation of their genes.A brief overview on IRM function across evolution.Genetic kidney diseases: Caenorhabditis elegans as model system.KLB, encoding β-Klotho, is mutated in patients with congenital hypogonadotropic hypogonadism.Life without nephrin: it's for the birds.Neph1 is reduced in primary focal segmental glomerulosclerosis, minimal change nephrotic syndrome, and corresponding experimental animal models of adriamycin-induced nephropathy and puromycin aminonucleoside nephrosis.The irre cell recognition module (IRM) protein Kirre is required to form the reciprocal synaptic network of L4 neurons in the Drosophila lamina.The Rst-Neph family of cell adhesion molecules in Gallus gallus.Cis-Heterodimerization of nephrin and KIRRELHeterodimerization of nephrin and KIRREL2; KIRREL3
P2860
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P2860
A model organism approach: defining the role of Neph proteins as regulators of neuron and kidney morphogenesis
description
2010 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հունիսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2010
@ast
im Juni 2010 veröffentlichter wissenschaftlicher Artikel
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scientific journal article
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vedecký článok (publikovaný 2010/06/15)
@sk
vědecký článek publikovaný v roce 2010
@cs
wetenschappelijk artikel (gepubliceerd op 2010/06/15)
@nl
наукова стаття, опублікована в червні 2010
@uk
مقالة علمية (نشرت في 15-6-2010)
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name
A model organism approach: def ...... euron and kidney morphogenesis
@ast
A model organism approach: def ...... euron and kidney morphogenesis
@en
A model organism approach: def ...... euron and kidney morphogenesis
@nl
type
label
A model organism approach: def ...... euron and kidney morphogenesis
@ast
A model organism approach: def ...... euron and kidney morphogenesis
@en
A model organism approach: def ...... euron and kidney morphogenesis
@nl
prefLabel
A model organism approach: def ...... euron and kidney morphogenesis
@ast
A model organism approach: def ...... euron and kidney morphogenesis
@en
A model organism approach: def ...... euron and kidney morphogenesis
@nl
P2093
P2860
P921
P356
P1476
A model organism approach: def ...... euron and kidney morphogenesis
@en
P2093
Alexander Ritter
Alexandra Müller
Björn Hartleben
Elke Neumann-Haefelin
Foteini Noutsou
Katrin Martin
Krasimir Slanchev
Markus Gödel
Nicola Wanner
P2860
P304
P356
10.1093/HMG/DDQ108
P577
2010-06-15T00:00:00Z