Cancer associated E17K mutation causes rapid conformational drift in AKT1 pleckstrin homology (PH) domain
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Bioinformatic Analysis of GJB2 Gene Missense Mutations.Molecular dynamic simulation reveals damaging impact of RAC1 F28L mutation in the switch I region.Bauerenol, a triterpenoid from Indian Suregada angustifolia: Induces reactive oxygen species-mediated P38MAPK activation and apoptosis in human hepatocellular carcinoma (HepG2) cells.Identification and analysis of driver missense mutations using rotation forest with feature selection.MiR-133b regulates bladder cancer cell proliferation and apoptosis by targeting Bcl-w and Akt1.Use of long term molecular dynamics simulation in predicting cancer associated SNPs.The expression and significance of Gal-3 and MUC1 in colorectal cancer and colon cancer.A Comprehensive In Silico Analysis on the Structural and Functional Impact of SNPs in the Congenital Heart Defects Associated with NKX2-5 Gene-A Molecular Dynamic Simulation Approach.AKT signaling in ERBB2-amplified breast cancer.AKT1 and BRAF mutations in pediatric aggressive fibromatosis.Oncogenic AKT1(E17K) mutation induces mammary hyperplasia but prevents HER2-driven tumorigenesis.AKT1 E17K in Colorectal Carcinoma Is Associated with BRAF V600E but Not MSI-H Status: A Clinicopathologic Comparison to PIK3CA Helical and Kinase Domain Mutants.Single nucleotide polymorphisms in microRNA binding sites of oncogenes: implications in cancer and pharmacogenomics.Computational SNP analysis: current approaches and future prospects.Single nucleotide polymorphism and its dynamics for pharmacogenomics.AKT in cancer: new molecular insights and advances in drug development.SMYD3-mediated lysine methylation in the PH domain is critical for activation of AKT1.Computational screening of disease-associated mutations in OCA2 gene.In silico analysis of miRNA-mediated gene regulation in OCA and OA genes.AKT kinase pathway: a leading target in cancer research.Unraveling the molecular effects of mutation L270P on Wiskkot-Aldrich syndrome protein: insights from molecular dynamics approach.
P2860
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P2860
Cancer associated E17K mutation causes rapid conformational drift in AKT1 pleckstrin homology (PH) domain
description
2013 nî lūn-bûn
@nan
2013 թուականին հրատարակուած գիտական յօդուած
@hyw
2013 թվականին հրատարակված գիտական հոդված
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2013年の論文
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2013年論文
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2013年論文
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2013年論文
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2013年論文
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2013年論文
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2013年论文
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name
Cancer associated E17K mutatio ...... leckstrin homology (PH) domain
@ast
Cancer associated E17K mutatio ...... leckstrin homology (PH) domain
@en
Cancer associated E17K mutatio ...... leckstrin homology (PH) domain
@nl
type
label
Cancer associated E17K mutatio ...... leckstrin homology (PH) domain
@ast
Cancer associated E17K mutatio ...... leckstrin homology (PH) domain
@en
Cancer associated E17K mutatio ...... leckstrin homology (PH) domain
@nl
prefLabel
Cancer associated E17K mutatio ...... leckstrin homology (PH) domain
@ast
Cancer associated E17K mutatio ...... leckstrin homology (PH) domain
@en
Cancer associated E17K mutatio ...... leckstrin homology (PH) domain
@nl
P2860
P3181
P1433
P1476
Cancer associated E17K mutatio ...... leckstrin homology (PH) domain
@en
P2093
Ambuj Kumar
Rituraj Purohit
P2860
P304
P3181
P356
10.1371/JOURNAL.PONE.0064364
P407
P577
2013-01-01T00:00:00Z