Metformin, a diabetes drug, eliminates tumor-initiating hepatocellular carcinoma cells
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Diabetes mellitus and metformin in hepatocellular carcinomaAnti-tumor effects of metformin in animal models of hepatocellular carcinoma: a systematic review and meta-analysisTurning hepatic cancer stem cells inside out--a deeper understanding through multiple perspectives.The Progress and Prospects of Putative Biomarkers for Liver Cancer Stem Cells in Hepatocellular CarcinomaMetformin as a cellular protector; a synoptic view of modern evidencesRole of metformin in suppressing 1,2-dimethylhydrazine-induced colon cancer in diabetic and non-diabetic mice: effect on tumor angiogenesis and cell proliferationMetformin may function as anti-cancer agent via targeting cancer stem cells: the potential biological significance of tumor-associated miRNAs in breast and pancreatic cancersMetformin repositioning as antitumoral agent: selective antiproliferative effects in human glioblastoma stem cells, via inhibition of CLIC1-mediated ion currentHepatocellular carcinoma: clinical frontiers and perspectives.In vitro and in vivo antiproliferative activity of metformin on stem-like cells isolated from spontaneous canine mammary carcinomas: translational implications for human tumorsMetformin suppresses diethylnitrosamine-induced liver tumorigenesis in obese and diabetic C57BL/KsJ-+Leprdb/+Leprdb mice.Targeting AMPK for cancer prevention and treatment.Diabetes Mellitus Predicts Occurrence of Cirrhosis and Hepatocellular Cancer in Alcoholic Liver and Non-alcoholic Fatty Liver Diseases.Metformin inhibits early stage diethylnitrosamine‑induced hepatocarcinogenesis in rats.Metformin prevents hepatocellular carcinoma development by suppressing hepatic progenitor cell activation in a rat model of cirrhosis.Liver Label Retaining Cancer Cells Are Relatively Resistant to the Reported Anti-Cancer Stem Cell Drug Metformin.A clinical perspective of the link between metabolic syndrome and hepatocellular carcinomaMetformin enhances the radiosensitivity of human liver cancer cells to γ-rays and carbon ion beams.Metformin promotes apoptosis in hepatocellular carcinoma through the CEBPD-induced autophagy pathway.Repositioning metformin in cancer: genetics, drug targets, and new ways of delivery.Cancer stem cells in hepatocellular carcinoma: Therapeutic implications based on stem cell biology.Metabolic Modification in Gastrointestinal Cancer Stem Cells: Characteristics and Therapeutic Approaches.Targeting cancer stem-like cells using dietary-derived agents - Where are we now?Mir-152 inhibits cell proliferation and colony formation of CD133(+) liver cancer stem cells by targeting KIT.Metformin inhibits the invasion of human hepatocellular carcinoma cells and enhances the chemosensitivity to sorafenib through a downregulation of the ERK/JNK-mediated NF-κB-dependent pathway that reduces uPA and MMP-9 expression.Additive impact of pre-liver transplant metabolic factors on survival post-liver transplant.Metformin requires 4E-BPs to induce apoptosis and repress translation of Mcl-1 in hepatocellular carcinoma cells.Metformin inhibition of neuroblastoma cell proliferation is differently modulated by cell differentiation induced by retinoic acid or overexpression of NDM29 non-coding RNA.Oncogene-Driven Metabolic Alterations in Cancer.Simvastatin and metformin inhibit cell growth in hepatitis C virus infected cells via mTOR increasing PTEN and autophagy.Development of an Injectable Slow-Release Metformin Formulation and Evaluation of Its Potential Antitumor Effects.Metformin reverses stem cell‑like HepG2 sphere formation and resistance to sorafenib by attenuating epithelial‑mesenchymal transformation
P2860
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P2860
Metformin, a diabetes drug, eliminates tumor-initiating hepatocellular carcinoma cells
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2013 nî lūn-bûn
@nan
2013 թուականին հրատարակուած գիտական յօդուած
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2013 թվականին հրատարակված գիտական հոդված
@hy
2013年の論文
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2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
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name
Metformin, a diabetes drug, eliminates tumor-initiating hepatocellular carcinoma cells
@ast
Metformin, a diabetes drug, eliminates tumor-initiating hepatocellular carcinoma cells
@en
Metformin, a diabetes drug, eliminates tumor-initiating hepatocellular carcinoma cells
@nl
type
label
Metformin, a diabetes drug, eliminates tumor-initiating hepatocellular carcinoma cells
@ast
Metformin, a diabetes drug, eliminates tumor-initiating hepatocellular carcinoma cells
@en
Metformin, a diabetes drug, eliminates tumor-initiating hepatocellular carcinoma cells
@nl
prefLabel
Metformin, a diabetes drug, eliminates tumor-initiating hepatocellular carcinoma cells
@ast
Metformin, a diabetes drug, eliminates tumor-initiating hepatocellular carcinoma cells
@en
Metformin, a diabetes drug, eliminates tumor-initiating hepatocellular carcinoma cells
@nl
P2093
P2860
P3181
P1433
P1476
Metformin, a diabetes drug, eliminates tumor-initiating hepatocellular carcinoma cells
@en
P2093
Akinobu Tawada
Atsushi Iwama
Eiichiro Suzuki
Fumihiko Kanai
Kaori Yuki
Motohiko Oshima
Motohisa Tada
Osamu Yokosuka
Sadahisa Ogasawara
Shuhei Koide
P2860
P304
P3181
P356
10.1371/JOURNAL.PONE.0070010
P407
P577
2013-01-01T00:00:00Z