Dynamic impacts of the inhibition of the molecular chaperone Hsp90 on the T-cell proteome have implications for anti-cancer therapy

Dynamic impacts of the inhibition of the molecular chaperone Hsp90 on the T-cell proteome have implications for anti-cancer therapy

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http://www.wikidata.org/entity/Q28535465
The Hsp90-dependent proteome is conserved and enriched for hub proteins with high levels of protein-protein connectivity.Protein networks and activation of lymphocytes.Characterization of CLL exosomes reveals a distinct microRNA signature and enhanced secretion by activation of BCR signalingQuantitative proteomics of heat-treated human cells show an across-the-board mild depletion of housekeeping proteins to massively accumulate few HSPsCombined HSP90 and kinase inhibitor therapy: Insights from The Cancer Genome Atlas.How Selective are Hsp90 Inhibitors for Cancer Cells over Normal Cells?Activation of Hsp90 Enzymatic Activity and Conformational Dynamics through Rationally Designed Allosteric Ligands.Chemically accessible hsp90 inhibitor that does not induce a heat shock responseTriazole Containing Novobiocin and Biphenyl Amides as Hsp90 C-Terminal Inhibitors.Effect of Morinda citrifolia (Noni)-Enriched Diet on Hepatic Heat Shock Protein and Lipid Metabolism-Related Genes in Heat Stressed Broiler Chickens.Proteomic Profiling of Hsp90 Inhibitors.Proteomic interrogation of HSP90 and insights for medical research.Multiplexed Proteome Dynamics Profiling Reveals Mechanisms Controlling Protein Homeostasis.Regulating the cytoprotective response in cancer cells using simultaneous inhibition of Hsp90 and Hsp70.
P2860

Dynamic impacts of the inhibition of the molecular chaperone Hsp90 on the T-cell proteome have implications for anti-cancer therapy

Item
http://www.wikidata.org/entity/Q28535465
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2013 nî lūn-bûn
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2013 թուականին հրատարակուած գիտական յօդուած
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2013 թվականին հրատարակված գիտական հոդված
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2013年の論文
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2013年論文
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2013年論文
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2013年論文
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2013年論文
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2013年論文
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2013年论文
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name
Dynamic impacts of the inhibit ...... ations for anti-cancer therapy
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Dynamic impacts of the inhibit ...... ations for anti-cancer therapy
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Dynamic impacts of the inhibit ...... ations for anti-cancer therapy
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type
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Dynamic impacts of the inhibit ...... ations for anti-cancer therapy
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Dynamic impacts of the inhibit ...... ations for anti-cancer therapy
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Dynamic impacts of the inhibit ...... ations for anti-cancer therapy
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Dynamic impacts of the inhibit ...... ations for anti-cancer therapy
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Dynamic impacts of the inhibit ...... ations for anti-cancer therapy
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Dynamic impacts of the inhibit ...... ations for anti-cancer therapy
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Dynamic impacts of the inhibit ...... ations for anti-cancer therapy
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10.1371/JOURNAL.PONE.0080425
P407
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P921
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