In-cell NMR characterization of the secondary structure populations of a disordered conformation of α-synuclein within E. coli cells
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Molecular determinants of α-synuclein mutants' oligomerization and membrane interactionsPhysicochemical properties of cells and their effects on intrinsically disordered proteins (IDPs)Probing protein quinary interactions by in-cell nuclear magnetic resonance spectroscopyIn-cell thermodynamics and a new role for protein surfaces.Quinary structure modulates protein stability in cells.Studying Intrinsically Disordered Proteins under True In Vivo Conditions by Combined Cross-Polarization and Carbonyl-Detection NMR Spectroscopy.A relationship between the transient structure in the monomeric state and the aggregation propensities of α-synuclein and β-synucleinPurification of α-synuclein from human brain reveals an instability of endogenous multimers as the protein approaches purity.The H50Q mutation induces a 10-fold decrease in the solubility of α-synuclein.Direct observation of the three regions in α-synuclein that determine its membrane-bound behaviour.The Differential Response of Proteins to Macromolecular CrowdingStructural characterization of the interaction of α-synuclein nascent chains with the ribosomal surface and trigger factorProtein folding on the ribosome studied using NMR spectroscopy.Structure, function and toxicity of alpha-synuclein: the Bermuda triangle in synucleinopathies.Implication of Alpha-Synuclein Phosphorylation at S129 in Synucleinopathies: What Have We Learned in the Last Decade?Insight into conformational modification of alpha-synuclein in the presence of neuronal whole cells and of their isolated membranes.Protein folding, binding, and droplet formation in cell-like conditions.Characterization of proteins by in-cell NMR spectroscopy in cultured mammalian cells.Hydrogen exchange of disordered proteins in Escherichia coli.HN-NCA heteronuclear TOCSY-NH experiment for (1)H(N) and (15)N sequential correlations in ((13)C, (15)N) labelled intrinsically disordered proteins.An approach to NMR assignment of intrinsically disordered proteins.Formation of covalent di-tyrosine dimers in recombinant α-synuclein.Intracellular pH modulates quinary structure.The PROSECCO server for chemical shift predictions in ordered and disordered proteins.Simultaneous quantification of protein order and disorder.Insights into the Molecular Mechanisms of Alzheimer's and Parkinson's Diseases with Molecular Simulations: Understanding the Roles of Artificial and Pathological Missense Mutations in Intrinsically Disordered Proteins Related to Pathology.Intrinsically Disordered Protein Exhibits Both Compaction and Expansion under Macromolecular Crowding.A Set of Efficient nD NMR Protocols for Resonance Assignments of Intrinsically Disordered Proteins.Studying Intrinsically Disordered Proteins under True In Vivo Conditions by Combined Cross-Polarization and Carbonyl-Detection NMR SpectroscopySer46-Phosphorylated MARCKS Is a Marker of Neurite Degeneration at the Pre-aggregation Stage in PD/DLB Pathologyα-Synuclein interacts directly but reversibly with psychosine: implications for α-synucleinopathies
P2860
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P2860
In-cell NMR characterization of the secondary structure populations of a disordered conformation of α-synuclein within E. coli cells
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2013 թուականին հրատարակուած գիտական յօդուած
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2013 թվականին հրատարակված գիտական հոդված
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2013年の論文
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2013年論文
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2013年論文
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2013年論文
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2013年論文
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2013年論文
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name
In-cell NMR characterization o ...... synuclein within E. coli cells
@ast
In-cell NMR characterization o ...... synuclein within E. coli cells
@en
In-cell NMR characterization o ...... synuclein within E. coli cells
@nl
type
label
In-cell NMR characterization o ...... synuclein within E. coli cells
@ast
In-cell NMR characterization o ...... synuclein within E. coli cells
@en
In-cell NMR characterization o ...... synuclein within E. coli cells
@nl
prefLabel
In-cell NMR characterization o ...... synuclein within E. coli cells
@ast
In-cell NMR characterization o ...... synuclein within E. coli cells
@en
In-cell NMR characterization o ...... synuclein within E. coli cells
@nl
P2093
P2860
P50
P3181
P1433
P1476
In-cell NMR characterization o ...... synuclein within E. coli cells
@en
P2093
Anthony W P Fitzpatrick
John Christodoulou
Lisa D Cabrita
P2860
P304
P3181
P356
10.1371/JOURNAL.PONE.0072286
P407
P577
2013-01-01T00:00:00Z