Multi-kinase inhibitor C1 triggers mitotic catastrophe of glioma stem cells mainly through MELK kinase inhibition
about
EZH2 protects glioma stem cells from radiation-induced cell death in a MELK/FOXM1-dependent mannerMELK-a conserved kinase: functions, signaling, cancer, and controversy.Glioblastoma stem cells (GSCs) epigenetic plasticity and interconversion between differentiated non-GSCs and GSCs.Kinase Gene Expression Profiling of Metastatic Clear Cell Renal Cell Carcinoma Tissue Identifies Potential New Therapeutic Targets.Discovery of benzo[e]pyridoindolones as kinase inhibitors that disrupt mitosis exit while erasing AMPK-Thr172 phosphorylation on the spindle.MELK kinase holds promise as a new radiosensitizing target and biomarker in triple-negative breast cancer.Identification of IL11RA and MELK amplification in gastric cancer by comprehensive genomic profiling of gastric cancer cell lines.MELK: a potential novel therapeutic target for TNBC and other aggressive malignancies.Maternal embryonic leucine zipper kinase inhibits epithelial-mesenchymal transition by regulating transforming growth factor-β signaling.Targeting Programmed Cell Death Using Small-Molecule Compounds to Improve Potential Cancer Therapy.FOXD1-ALDH1A3 Signaling Is a Determinant for the Self-Renewal and Tumorigenicity of Mesenchymal Glioma Stem Cells.Divergent evolution of temozolomide resistance in glioblastoma stem cells is reflected in extracellular vesicles and coupled with radiosensitization.Targeting dual specificity protein kinase TTK attenuates tumorigenesis of glioblastoma.Challenges in validating candidate therapeutic targets in cancer.
P2860
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P2860
Multi-kinase inhibitor C1 triggers mitotic catastrophe of glioma stem cells mainly through MELK kinase inhibition
description
2014 nî lūn-bûn
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2014 թուականին հրատարակուած գիտական յօդուած
@hyw
2014 թվականին հրատարակված գիտական հոդված
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2014年の論文
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2014年論文
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2014年論文
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2014年論文
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2014年論文
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2014年論文
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2014年论文
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name
Multi-kinase inhibitor C1 trig ...... through MELK kinase inhibition
@ast
Multi-kinase inhibitor C1 trig ...... through MELK kinase inhibition
@en
Multi-kinase inhibitor C1 trig ...... through MELK kinase inhibition
@nl
type
label
Multi-kinase inhibitor C1 trig ...... through MELK kinase inhibition
@ast
Multi-kinase inhibitor C1 trig ...... through MELK kinase inhibition
@en
Multi-kinase inhibitor C1 trig ...... through MELK kinase inhibition
@nl
prefLabel
Multi-kinase inhibitor C1 trig ...... through MELK kinase inhibition
@ast
Multi-kinase inhibitor C1 trig ...... through MELK kinase inhibition
@en
Multi-kinase inhibitor C1 trig ...... through MELK kinase inhibition
@nl
P2093
P2860
P3181
P1433
P1476
Multi-kinase inhibitor C1 trig ...... through MELK kinase inhibition
@en
P2093
Chi-Hung Nguyen
Christopher Hong
Harley I Kornblum
Ichiro Nakano
Kaushal Joshi
Mariko Nakano-Okuno
Mutsuko Minata
P2860
P304
P3181
P356
10.1371/JOURNAL.PONE.0092546
P407
P50
P577
2014-04-16T00:00:00Z