Ovarian cancer spheroid cells with stem cell-like properties contribute to tumor generation, metastasis and chemotherapy resistance through hypoxia-resistant metabolism
about
Phytochemical modulators of mitochondria: the search for chemopreventive agents and supportive therapeuticsCancer stem cell metabolismTumorsphere as an effective in vitro platform for screening anti-cancer stem cell drugsAldehyde dehydrogenase as a marker and functional mediator of metastasis in solid tumorsIn vivo molecular imaging of cancer stem cellsBroad targeting of angiogenesis for cancer prevention and therapyControl of Tumor Initiation by NKG2D Naturally Expressed on Ovarian Cancer Cells.Metformin against cancer stem cells through the modulation of energy metabolism: special considerations on ovarian cancer.Ovarian cancer stem cells express ROR1, which can be targeted for anti-cancer-stem-cell therapy.CXCL12/CXCR4 blockade by oncolytic virotherapy inhibits ovarian cancer growth by decreasing immunosuppression and targeting cancer-initiating cells.Developing ovarian cancer stem cell models: laying the pipeline from discovery to clinical intervention.OVCAR-3 spheroid-derived cells display distinct metabolic profilesIn vitro enrichment of ovarian cancer tumor-initiating cellsReversal of anchorage-independent multicellular spheroid into a monolayer mimics a metastatic model.MCT1 promotes the cisplatin-resistance by antagonizing Fas in epithelial ovarian cancer.Bruton's tyrosine kinase (Btk) inhibitor ibrutinib suppresses stem-like traits in ovarian cancer.Inhibition of Fatty Acid Synthase Decreases Expression of Stemness Markers in Glioma Stem Cells.A critical role of Oct4A in mediating metastasis and disease-free survival in a mouse model of ovarian cancer.An apoptosis-enhancing drug overcomes platinum resistance in a tumour-initiating subpopulation of ovarian cancer.AAV9 delivering a modified human Mullerian inhibiting substance as a gene therapy in patient-derived xenografts of ovarian cancerSmall molecule inhibitor of the bone morphogenetic protein pathway DMH1 reduces ovarian cancer cell growthCancer Stem Cells in Small Cell Lung Cancer Cell Line H446: Higher Dependency on Oxidative Phosphorylation and Mitochondrial Substrate-Level Phosphorylation than Non-Stem Cancer CellsGenome-wide RNAi screening identifies TMIGD3 isoform1 as a suppressor of NF-κB and osteosarcoma progressionMethoxyphenyl chalcone sensitizes aggressive epithelial cancer to cisplatin through apoptosis induction and cancer stem cell eradication.Monitoring cancer stem cells: insights into clinical oncology.Evidence for differential viral oncolytic efficacy in an in vitro model of epithelial ovarian cancer metastasisModulation of anti-cancer drug sensitivity through the regulation of mitochondrial activity by adenylate kinase 4.MiRNA Transcriptome Profiling of Spheroid-Enriched Cells with Cancer Stem Cell Properties in Human Breast MCF-7 Cell Line.FOXP1 functions as an oncogene in promoting cancer stem cell-like characteristics in ovarian cancer cellsSpheroid-plug model as a tool to study tumor development, angiogenesis, and heterogeneity in vivo.Low-dose cisplatin-induced CXCR4 expression promotes proliferation of ovarian cancer stem-like cells.Isolation and characterization of renal cancer stem cells from patient-derived xenograftsLiquid-based three-dimensional tumor models for cancer research and drug discovery.miR-509-3p is clinically significant and strongly attenuates cellular migration and multi-cellular spheroids in ovarian cancer.Chronic arsenic trioxide exposure leads to enhanced aggressiveness via Met oncogene addiction in cancer cells.HIF-1-alpha links mitochondrial perturbation to the dynamic acquisition of breast cancer tumorigenicity.NANOG regulates epithelial-mesenchymal transition and chemoresistance in ovarian cancerHypoxia-NOTCH1-SOX2 signaling is important for maintaining cancer stem cells in ovarian cancer.Ovarian cancer stem cells: still an elusive entity?The metabolic landscape of cancer stem cells.
P2860
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P2860
Ovarian cancer spheroid cells with stem cell-like properties contribute to tumor generation, metastasis and chemotherapy resistance through hypoxia-resistant metabolism
description
2014 nî lūn-bûn
@nan
2014 թուականին հրատարակուած գիտական յօդուած
@hyw
2014 թվականին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Ovarian cancer spheroid cells ...... h hypoxia-resistant metabolism
@ast
Ovarian cancer spheroid cells ...... h hypoxia-resistant metabolism
@en
Ovarian cancer spheroid cells ...... h hypoxia-resistant metabolism
@nl
type
label
Ovarian cancer spheroid cells ...... h hypoxia-resistant metabolism
@ast
Ovarian cancer spheroid cells ...... h hypoxia-resistant metabolism
@en
Ovarian cancer spheroid cells ...... h hypoxia-resistant metabolism
@nl
prefLabel
Ovarian cancer spheroid cells ...... h hypoxia-resistant metabolism
@ast
Ovarian cancer spheroid cells ...... h hypoxia-resistant metabolism
@en
Ovarian cancer spheroid cells ...... h hypoxia-resistant metabolism
@nl
P2093
P2860
P921
P3181
P1433
P1476
Ovarian cancer spheroid cells ...... h hypoxia-resistant metabolism
@en
P2093
Carl D Morrison
Jianqun Liao
Nana Tchabo
Paulette Mhawech-Fauceglia
Shashikant B Lele
Wendy J Huss
Xinhui Wang
Zikun Qian
P2860
P304
P3181
P356
10.1371/JOURNAL.PONE.0084941
P407
P50
P577
2014-01-01T00:00:00Z