Chemical and genetic validation of the statin drug target to treat the helminth disease, schistosomiasis
about
The diterpenoid 7-keto-sempervirol, derived from Lycium chinense, displays anthelmintic activity against both Schistosoma mansoni and Fasciola hepaticaActivity Profile of an FDA-Approved Compound Library against Schistosoma mansoniApplication of RNAi to Genomic Drug Target Validation in SchistosomesStructure-Bioactivity Relationship for Benzimidazole Thiophene Inhibitors of Polo-Like Kinase 1 (PLK1), a Potential Drug Target in Schistosoma mansoniImage Harvest: an open-source platform for high-throughput plant image processing and analysisReconstructing the Temporal Progression of Biological Data Using Cluster Spanning Trees.Serum albumin and α-1 acid glycoprotein impede the killing of Schistosoma mansoni by the tyrosine kinase inhibitor ImatinibSynthesis of a sugar-based thiosemicarbazone series and structure-activity relationship versus the parasite cysteine proteases rhodesain, cruzain, and Schistosoma mansoni cathepsin B1.Defining the Schistosoma haematobium kinome enables the prediction of essential kinases as anti-schistosome drug targets.Excretion/secretion products from Schistosoma mansoni adults, eggs and schistosomula have unique peptidase specificity profiles.The genome of Onchocerca volvulus, agent of river blindness.Anthelmintic drug discovery: into the future.Target-based molecular modeling strategies for schistosomiasis drug discovery.Repurposing pharma assets: an accelerated mechanism for strengthening the schistosomiasis drug development pipeline.Antischistosomal agents: state of art and perspectives.Drug Repurposing for Schistosomiasis: Combinations of Drugs or Biomolecules.Design, Synthesis, and Characterization of Novel Small Molecules as Broad Range Antischistosomal Agents
P2860
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P2860
Chemical and genetic validation of the statin drug target to treat the helminth disease, schistosomiasis
description
2014 nî lūn-bûn
@nan
2014 թուականին հրատարակուած գիտական յօդուած
@hyw
2014 թվականին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Chemical and genetic validatio ...... minth disease, schistosomiasis
@ast
Chemical and genetic validatio ...... minth disease, schistosomiasis
@en
Chemical and genetic validatio ...... minth disease, schistosomiasis
@nl
type
label
Chemical and genetic validatio ...... minth disease, schistosomiasis
@ast
Chemical and genetic validatio ...... minth disease, schistosomiasis
@en
Chemical and genetic validatio ...... minth disease, schistosomiasis
@nl
prefLabel
Chemical and genetic validatio ...... minth disease, schistosomiasis
@ast
Chemical and genetic validatio ...... minth disease, schistosomiasis
@en
Chemical and genetic validatio ...... minth disease, schistosomiasis
@nl
P2093
P2860
P3181
P1433
P1476
Chemical and genetic validatio ...... minth disease, schistosomiasis
@en
P2093
Brian M Suzuki
Conor R Caffrey
Rahul Singh
Thavy Long
P2860
P304
P3181
P356
10.1371/JOURNAL.PONE.0087594
P407
P577
2014-01-29T00:00:00Z