Identification of host-targeted small molecules that restrict intracellular Mycobacterium tuberculosis growth
about
Immunotherapy for tuberculosis: future prospectsNext-generation antimicrobials: from chemical biology to first-in-class drugsTherapeutic targeting of autophagy in neurodegenerative and infectious diseasesGranulomas and Inflammation: Host-Directed Therapies for Tuberculosis.The cell biology of late blight diseaseContribution of high-content imaging technologies to the development of anti-infective drugsImmune Cell Regulatory Pathways Unexplored as Host-Directed Therapeutic Targets for Mycobacterium tuberculosis: An Opportunity to Apply Precision Medicine Innovations to Infectious DiseasesImmunomodulatory effects mediated by serotoninProtection and pathology in TB: learning from the zebrafish modelCell death and autophagy in tuberculosisNew insights into TB physiology suggest untapped therapeutic opportunitiesMethyl-hydroxylamine as an efficacious antibacterial agent that targets the ribonucleotide reductase enzymexCT increases tuberculosis susceptibility by regulating antimicrobial function and inflammationNovel cell-based in vitro screen to identify small-molecule inhibitors against intracellular replication of Cryptococcus neoformans in macrophagesNew tricks for old dogs: countering antibiotic resistance in tuberculosis with host-directed therapeuticsThe Tyrosine Kinase Inhibitor Gefitinib Restricts Mycobacterium tuberculosis Growth through Increased Lysosomal Biogenesis and Modulation of Cytokine Signaling.Combination therapy for tuberculosis treatment: pulmonary administration of ethionamide and booster co-loaded nanoparticles.Gefitinib inhibits the growth of Toxoplasma gondii in HeLa cells.Cell-autonomous effector mechanisms against mycobacterium tuberculosis.Advancing host-directed therapy for tuberculosis.Differential transcriptional response in macrophages infected with cell wall deficient versus normal Mycobacterium Tuberculosis.Paroxetine differentially modulates LPS-induced TNFα and IL-6 production in mouse macrophages.Mycobacterium tuberculosis metabolismAutophagy in the fight against tuberculosis.Autophagy in Mycobacterium tuberculosis and HIV infectionsScreen of FDA-approved drug library identifies maprotiline, an antibiofilm and antivirulence compound with QseC sensor-kinase dependent activity in Francisella novicida.Advances in discovering small molecules to probe protein function in a systems context.Selective enrichment of mycobacterial proteins from infected host macrophages.N-Desmethylclozapine, Fluoxetine, and Salmeterol Inhibit Postentry Stages of the Dengue Virus Life Cycle.Bis-biguanide dihydrochloride inhibits intracellular replication of M. tuberculosis and controls infection in miceSystematic, multiparametric analysis of Mycobacterium tuberculosis intracellular infection offers insight into coordinated virulenceTargeting Batf2 for infectious diseases and cancer.A tug-of-war between the host and the pathogen generates strategic hotspots for the development of novel therapeutic interventions against infectious diseases.Fine-tuning of macrophage activation using synthetic rocaglate derivatives.Mycobacterium tuberculosis induces the miR-33 locus to reprogram autophagy and host lipid metabolism.Targeting Drug-Sensitive and -Resistant Strains of Mycobacterium tuberculosis by Inhibition of Src Family Kinases Lowers Disease Burden and PathologyPlasma Membrane Profiling Reveals Upregulation of ABCA1 by Infected Macrophages Leading to Restriction of Mycobacterial Growth.Genetic-and-Epigenetic Interspecies Networks for Cross-Talk Mechanisms in Human Macrophages and Dendritic Cells during MTB Infection.The future for early-stage tuberculosis drug discoveryMacrophage defense mechanisms against intracellular bacteria.
P2860
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P2860
Identification of host-targeted small molecules that restrict intracellular Mycobacterium tuberculosis growth
description
2014 nî lūn-bûn
@nan
2014 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Identification of host-targete ...... obacterium tuberculosis growth
@ast
Identification of host-targete ...... obacterium tuberculosis growth
@en
Identification of host-targete ...... obacterium tuberculosis growth
@nl
type
label
Identification of host-targete ...... obacterium tuberculosis growth
@ast
Identification of host-targete ...... obacterium tuberculosis growth
@en
Identification of host-targete ...... obacterium tuberculosis growth
@nl
prefLabel
Identification of host-targete ...... obacterium tuberculosis growth
@ast
Identification of host-targete ...... obacterium tuberculosis growth
@en
Identification of host-targete ...... obacterium tuberculosis growth
@nl
P2093
P2860
P3181
P1433
P1476
Identification of host-targete ...... obacterium tuberculosis growth
@en
P2093
Amy K Barczak
Christopher B Moore
Deborah T Hung
Eric J Rubin
Kimberly Sogi
Mark-Anthony Bray
Martha Vokes
Noman Siddiqi
Samantha S Luo
Sarah A Stanley
P2860
P304
P3181
P356
10.1371/JOURNAL.PPAT.1003946
P407
P577
2014-02-01T00:00:00Z