The histone deacetylase inhibitor, Vorinostat, represses hypoxia inducible factor 1 alpha expression through translational inhibition - Wikidata - awgldk - TriplyDB

The histone deacetylase inhibitor, Vorinostat, represses hypoxia inducible factor 1 alpha expression through translational inhibition

The histone deacetylase inhibitor, Vorinostat, represses hypoxia inducible factor 1 alpha expression through translational inhibition

http://www.wikidata.org/entity/Q28542639

about

Epigenetic Therapy for Solid Tumors: Highlighting the Impact of Tumor Hypoxia The centrosomal OFD1 protein interacts with the translation machinery and regulates the synthesis of specific targets.ERAD defects and the HFE-H63D variant are associated with increased risk of liver damages in Alpha 1-Antitrypsin Deficiency 5-Azacitidine induces demethylation of PTPL1 and inhibits growth in non-Hodgkin lymphoma.Novel chemoimmunotherapeutic strategy for hepatocellular carcinoma based on a genome-wide association study Acetazolamide potentiates the anti-tumor potential of HDACi, MS-275, in neuroblastoma The epigenetic regulation of HIF-1α by SIRT1 in MPP(+) treated SH-SY5Y cells Targeting HDAC with a novel inhibitor effectively reverses paclitaxel resistance in non-small cell lung cancer via multiple mechanisms Class I and IIa HDACs Mediate HIF-1α Stability Through PHD2-Dependent Mechanism, While HDAC6, a Class IIb Member, Promotes HIF-1α Transcriptional Activity in Nucleus Pulposus Cells of the Intervertebral Disc.HIF-1α inhibition by 2-methoxyestradiol induces cell death via activation of the mitochondrial apoptotic pathway in acute myeloid leukemia.Isobolographic analysis demonstrates additive effect of cisplatin and HDIs combined treatment augmenting their anti-cancer activity in lung cancer cell lines.Development of Inhibitors Targeting Hypoxia-Inducible Factor 1 and 2 for Cancer Therapy.Histone deacetylase inhibitors in hematological malignancies and solid tumors.HDAC6 regulates sensitivity to cell death in response to stress and post-stress recovery Vorinostat suppresses hypoxia signaling by modulating nuclear translocation of hypoxia inducible factor 1 alpha.Hypoxia-inducible factor 1 alpha promotes cancer stem cells-like properties in human ovarian cancer cells by upregulating SIRT1 expression Melatonin enhances sorafenib actions in human hepatocarcinoma cells by inhibiting mTORC1/p70S6K/HIF-1α and hypoxia-mediated mitophagy.Histone Deacetylase Inhibitor-Induced Autophagy in Tumor Cells: Implications for p53.The mechanism and potential targets of class II HDACs in angiogenesis."Vessels in the Storm": Searching for Prognostic and Predictive Angiogenic Factors in Colorectal Cancer.A quantitative LumiFluo assay to test inhibitory compounds blocking p53 degradation induced by human papillomavirus oncoprotein E6 in living cells.

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The histone deacetylase inhibitor, Vorinostat, represses hypoxia inducible factor 1 alpha expression through translational inhibition

http://www.wikidata.org/entity/Q28542639

description

2014 nî lūn-bûn

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2014 թուականին հրատարակուած գիտական յօդուած

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2014 թվականին հրատարակված գիտական հոդված

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2014年の論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年论文

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name

The histone deacetylase inhibi ...... rough translational inhibition

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The histone deacetylase inhibi ...... rough translational inhibition

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The histone deacetylase inhibi ...... rough translational inhibition

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type

label

The histone deacetylase inhibi ...... rough translational inhibition

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The histone deacetylase inhibi ...... rough translational inhibition

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The histone deacetylase inhibi ...... rough translational inhibition

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prefLabel

The histone deacetylase inhibi ...... rough translational inhibition

@ast

The histone deacetylase inhibi ...... rough translational inhibition

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The histone deacetylase inhibi ...... rough translational inhibition

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The histone deacetylase inhibi ...... rough translational inhibition

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Daniela Martino Roth

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Darren M Hutt

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Hélène Vignaud

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Marion Bouchecareilh

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PML inhibits HIF-1alpha translation and neoangiogenesis through repression of mTOR

Reconstitution reveals the functional core of mammalian eIF3

Control of Paip1-eukayrotic translation initiation factor 3 interaction by amino acids through S6 kinase

Regulation of tumor angiogenesis by p53-induced degradation of hypoxia-inducible factor 1alpha

Reduced histone deacetylase 7 activity restores function to misfolded CFTR in cystic fibrosis

Histone deacetylase inhibitor (HDACi) suberoylanilide hydroxamic acid (SAHA)-mediated correction of α1-antitrypsin deficiency

Hypoxia-inducible factor determines sensitivity to inhibitors of mTOR in kidney cancer.

Targeting HIF-1 for cancer therapy

Sorafenib in advanced hepatocellular carcinoma

Loss of PTEN facilitates HIF-1-mediated gene expression

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e106224

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scholarly article

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10.1371/JOURNAL.PONE.0106224

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Christophe Cullin

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