The high-affinity D2/D3 agonist D512 protects PC12 cells from 6-OHDA-induced apoptotic cell death and rescues dopaminergic neurons in the MPTP mouse model of Parkinson's disease

The high-affinity D2/D3 agonist D512 protects PC12 cells from 6-OHDA-induced apoptotic cell death and rescues dopaminergic neurons in the MPTP mouse model of Parkinson's disease

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http://www.wikidata.org/entity/Q28543195
Carriers of a common variant in the dopamine transporter gene have greater dementia risk, cognitive decline, and faster ventricular expansion.Cortex Fraxini (Qingpi) Protects Rat Pheochromocytoma Cells against 6-Hydroxydopamine-Induced ApoptosisAdvances and challenges in the search for D2 and D3 dopamine receptor-selective compounds.D-512, a novel dopamine D2/3 receptor agonist, demonstrates greater anti-Parkinsonian efficacy than ropinirole in Parkinsonian rats.The MPTP Story.Neurotoxin mechanisms and processes relevant to Parkinson's disease: an update.Assessment of Protective Role of Multifunctional Dopamine Agonist D-512 Against Oxidative Stress Produced by Depletion of Glutathione in PC12 Cells: Implication in Neuroprotective Therapy for Parkinson's Disease.Induction of ferroptosis and mitochondrial dysfunction by oxidative stress in PC12 cells.A novel iron (II) preferring dopamine agonist chelator D-607 significantly suppresses α-syn- and MPTP-induced toxicities in vivo.
P2860

The high-affinity D2/D3 agonist D512 protects PC12 cells from 6-OHDA-induced apoptotic cell death and rescues dopaminergic neurons in the MPTP mouse model of Parkinson's disease

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http://www.wikidata.org/entity/Q28543195
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2014 nî lūn-bûn
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2014 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
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2014 թվականի հոտեմբերին հրատարակված գիտական հոդված
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2014年の論文
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2014年論文
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2014年論文
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2014年論文
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The high-affinity D2/D3 agonis ...... e model of Parkinson's disease
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The high-affinity D2/D3 agonis ...... e model of Parkinson's disease
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The high-affinity D2/D3 agonis ...... e model of Parkinson's disease
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label
The high-affinity D2/D3 agonis ...... e model of Parkinson's disease
@ast
The high-affinity D2/D3 agonis ...... e model of Parkinson's disease
@en
The high-affinity D2/D3 agonis ...... e model of Parkinson's disease
@nl
prefLabel
The high-affinity D2/D3 agonis ...... e model of Parkinson's disease
@ast
The high-affinity D2/D3 agonis ...... e model of Parkinson's disease
@en
The high-affinity D2/D3 agonis ...... e model of Parkinson's disease
@nl
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P1476
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P1433
P1476
The high-affinity D2/D3 agonis ...... e model of Parkinson's disease
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P698
P921
P932