Piperlongumine Blocks JAK2-STAT3 to Inhibit Collagen-Induced Platelet Reactivity Independent of Reactive Oxygen Species

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The effects of signal transducer and activator of transcription three mutations on human platelets.Correction: Piperlongumine Blocks JAK2-STAT3 to Inhibit Collagen-Induced Platelet Reactivity Independent of Reactive Oxygen Species†.

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Q41993160-DA23CA5B-920C-4CC2-B495-E7572179950B Q43107071-F18B47FA-4DE5-486A-8573-BB21AA73147E

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Piperlongumine Blocks JAK2-STAT3 to Inhibit Collagen-Induced Platelet Reactivity Independent of Reactive Oxygen Species

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Piperlongumine Blocks JAK2-STA ...... ent of Reactive Oxygen Species

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Piperlongumine Blocks JAK2-STA ...... ent of Reactive Oxygen Species

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Piperlongumine Blocks JAK2-STA ...... ent of Reactive Oxygen Species

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Piperlongumine Blocks JAK2-STA ...... ent of Reactive Oxygen Species

@ast

Piperlongumine Blocks JAK2-STA ...... ent of Reactive Oxygen Species

@en

Piperlongumine Blocks JAK2-STA ...... ent of Reactive Oxygen Species

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Piperlongumine Blocks JAK2-STA ...... ent of Reactive Oxygen Species

@ast

Piperlongumine Blocks JAK2-STA ...... ent of Reactive Oxygen Species

@en

Piperlongumine Blocks JAK2-STA ...... ent of Reactive Oxygen Species

@nl

P1476

Piperlongumine Blocks JAK2-STA ...... ent of Reactive Oxygen Species

@en

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David J Tweardy

http://www.w3.org/2001/XMLSchema#string

Hengjie Yuan

http://www.w3.org/2001/XMLSchema#string

Jianning Zhang

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Jing-fei Dong

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Katie L Houck

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Ken Hull

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Mingzhao Zhu

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Uddalak Bharadwaj

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Xiaoping Wu

http://www.w3.org/2001/XMLSchema#string

Xiaoyun Fu

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P2860

RETRACTED: Selective killing of cancer cells by a small molecule targeting the stress response to ROS

Maximal activation of transcription by Stat1 and Stat3 requires both tyrosine and serine phosphorylation

Stat3: a STAT family member activated by tyrosine phosphorylation in response to epidermal growth factor and interleukin-6

Signal transducer and activator of transcription 3 (STAT3) regulates collagen-induced platelet aggregation independently of its transcription factor activity.

Drug-repositioning screening identified piperlongumine as a direct STAT3 inhibitor with potent activity against breast cancer.

Association of transcription factor APRF and protein kinase Jak1 with the interleukin-6 signal transducer gp130.

Inhibitory effect of piperlonguminine on melanin production in melanoma B16 cell line by downregulation of tyrosinase expression.

Synthesis, cellular evaluation, and mechanism of action of piperlongumine analogs.

Piperlongumine inhibits atherosclerotic plaque formation and vascular smooth muscle cell proliferation by suppressing PDGF receptor signaling.

Tracking STAT nuclear traffic.

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e0143964

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scholarly article

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10.1371/JOURNAL.PONE.0143964

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English

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http://www.w3.org/2001/XMLSchema#string

P478

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Daniel Romo

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2015-12-08T00:00:00Z

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286498355

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26645674

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P932

4672935

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Piperlongumine Blocks JAK2-STAT3 to Inhibit Collagen-Induced Platelet Reactivity Independent of Reactive Oxygen Species

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P2860

P2860

Piperlongumine Blocks JAK2-STAT3 to Inhibit Collagen-Induced Platelet Reactivity Independent of Reactive Oxygen Species

description

name

type

label

prefLabel

P1433

P1476

P2093

P2860

P304

P31

P356

P407

P433

P478

P50

P577

P5875

P698

P932

P356

P1433

P1476

P2093

P2860

P304

P31

P356

P407

P433

P478

P50

P577

P5875

P698

P932