The functions of five distinct mammalian phospholipase A2S in regulating arachidonic acid release. Type IIa and type V secretory phospholipase A2S are functionally redundant and act in concert with cytosolic phospholipase A2
about
Cloning and characterization of novel mouse and human secretory phospholipase A(2)sStructures, enzymatic properties, and expression of novel human and mouse secretory phospholipase A(2)sCloning and recombinant expression of a structurally novel human secreted phospholipase A2The molecular basis of phosphatidylcholine preference of human group-V phospholipase A2VEGF stimulation of endothelial cell PAF synthesis is mediated by group V 14 kDa secretory phospholipase A2Phospholipase A2 enzymes: physical structure, biological function, disease implication, chemical inhibition, and therapeutic interventionD-Tyrosine as a chiral precusor to potent inhibitors of human nonpancreatic secretory phospholipase A2 (IIa) with antiinflammatory activityNovel contraceptive targets to inhibit ovulation: the prostaglandin E2 pathwayCell-specific expression of group X and group V secretory phospholipases A(2) in human lung airway epithelial cellsLow molecular weight group IIA and group V phospholipase A(2) enzymes have different intracellular locations in mouse bone marrow-derived mast cellsHuman group V phospholipase A2 induces group IVA phospholipase A2-independent cysteinyl leukotriene synthesis in human eosinophilsGroup V phospholipase A2 induces leukotriene biosynthesis in human neutrophils through the activation of group IVA phospholipase A2Fcgamma RI-triggered generation of arachidonic acid and eicosanoids requires iPLA2 but not cPLA2 in human monocytic cellsPhospholipases of mineralization competent cells and matrix vesicles: roles in physiological and pathological mineralizationsThe role of phospholipases A2 in schizophreniaSkeletal muscle necrosis and regeneration after injection of Thalassophryne nattereri (niquim) fish venom in miceUnique membrane interaction mode of group IIF phospholipase A2Group V Secretory Phospholipase A2 Is Involved in Tubular Integrity and Sodium Handling in the KidneyChronic fluoxetine upregulates activity, protein and mRNA levels of cytosolic phospholipase A2 in rat frontal cortexBiosynthesis of anandamide and N-palmitoylethanolamine by sequential actions of phospholipase A2 and lysophospholipase DDomain-induced activation of human phospholipase A2 type IIA: local versus global lipid composition.Toward understanding interfacial activation of secretory phospholipase A2 (PLA2): membrane surface properties and membrane-induced structural changes in the enzyme contribute synergistically to PLA2 activationCytosolic phospholipase A2 alpha inhibition prevents neuronal NMDA receptor-stimulated arachidonic acid mobilization and prostaglandin production but not subsequent cell death.Chronic SSRI stimulation of astrocytic 5-HT2B receptors change multiple gene expressions/editings and metabolism of glutamate, glucose and glycogen: a potential paradigm shift.A decrease in remodeling accounts for the accumulation of arachidonic acid in murine mast cells undergoing apoptosis.Arachidonic acid release from mammalian cells transfected with human groups IIA and X secreted phospholipase A(2) occurs predominantly during the secretory process and with the involvement of cytosolic phospholipase A(2)-alpha.Highly selective hydrolysis of fatty acyl-CoAs by calcium-independent phospholipase A2beta. Enzyme autoacylation and acyl-CoA-mediated reversal of calmodulin inhibition of phospholipase A2 activity.A-002 (Varespladib), a phospholipase A2 inhibitor, reduces atherosclerosis in guinea pigs.Role of secretory phospholipase a(2) in CNS inflammation: implications in traumatic spinal cord injury.Mood-stabilizers target the brain arachidonic acid cascade.Thrombin and activated protein C inhibit the expression of secretory group IIA phospholipase A(2) in the TNF-alpha-activated endothelial cells by EPCR and PAR-1 dependent mechanismsEarly immune responses are independent of RGC dysfunction in glaucoma with complement component C3 being protective.Phospholipase A2 enzymes in eicosanoid generation.Distinct role of Kruppel-like factor 11 in the regulation of prostaglandin E2 biosynthesis.Role of group V phospholipase A2 in zymosan-induced eicosanoid generation and vascular permeability revealed by targeted gene disruption.Novel immunomodulators for topical skin disease therapy.Cellular arachidonate-releasing function of novel classes of secretory phospholipase A2s (groups III and XII).Pyrimidinoceptor potentiation of macrophage PGE(2) release involved in the induction of nitric oxide synthaseThe MAP kinase inhibitors, PD098059, UO126 and SB203580, inhibit IL-1beta-dependent PGE(2) release via mechanistically distinct processes.Comparative protection against rat intestinal reperfusion injury by a new inhibitor of sPLA2, COX-1 and COX-2 selective inhibitors, and an LTC4 receptor antagonist
P2860
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P2860
The functions of five distinct mammalian phospholipase A2S in regulating arachidonic acid release. Type IIa and type V secretory phospholipase A2S are functionally redundant and act in concert with cytosolic phospholipase A2
description
1998 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի հունիսին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
artículu científicu espublizáu en 1998
@ast
im Juni 1998 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 1998/06/05)
@sk
vědecký článek publikovaný v roce 1998
@cs
wetenschappelijk artikel (gepubliceerd op 1998/06/05)
@nl
наукова стаття, опублікована в червні 1998
@uk
name
The functions of five distinct ...... ith cytosolic phospholipase A2
@ast
The functions of five distinct ...... ith cytosolic phospholipase A2
@en
The functions of five distinct ...... ith cytosolic phospholipase A2
@nl
type
label
The functions of five distinct ...... ith cytosolic phospholipase A2
@ast
The functions of five distinct ...... ith cytosolic phospholipase A2
@en
The functions of five distinct ...... ith cytosolic phospholipase A2
@nl
prefLabel
The functions of five distinct ...... ith cytosolic phospholipase A2
@ast
The functions of five distinct ...... ith cytosolic phospholipase A2
@en
The functions of five distinct ...... ith cytosolic phospholipase A2
@nl
P2093
P356
P1476
The functions of five distinct ...... ith cytosolic phospholipase A2
@en
P2093
J. A. Tischfield
M. Murakami
M. V. Winstead
S. Shimbara
P304
14411–14423
P356
10.1074/JBC.273.23.14411
P407
P577
1998-06-05T00:00:00Z