Adenosine A2a blockade prevents synergy between mu-opiate and cannabinoid CB1 receptors and eliminates heroin-seeking behavior in addicted rats
about
Heteromerization of G protein-coupled receptors: relevance to neurological disorders and neurotherapeutics.Cannabinoids in health and diseaseThe endocannabinoid system as an emerging target of pharmacotherapyLooking for the role of cannabinoid receptor heteromers in striatal functionAdenosine A2A receptors in ventral striatum, hypothalamus and nociceptive circuitry implications for drug addiction, sleep and painEffect of Pharmacological Modulation of the Endocannabinoid System on Opiate Withdrawal: A Review of the Preclinical Animal LiteratureRole of cues and contexts on drug-seeking behaviourActivators of G protein signaling exhibit broad functionality and define a distinct core signaling triadAdenosine A(2A) receptors and their role in drug addictionThe PDZ and band 4.1 containing protein Frmpd1 regulates the subcellular location of activator of G-protein signaling 3 and its interaction with G-proteinsUp-regulation of AGS3 during morphine withdrawal promotes cAMP superactivation via adenylyl cyclase 5 and 7 in rat nucleus accumbens/striatal neuronsEndogenous opiates and behavior: 2006Cue-conditioned alcohol seeking in rats following abstinence: involvement of metabotropic glutamate 5 receptors.Distribution of activator of G-protein signaling 3 within the aggresomal pathway: role of specific residues in the tetratricopeptide repeat domain and differential regulation by the AGS3 binding partners Gi(alpha) and mammalian inscuteable.Receptor-regulated interaction of activator of G-protein signaling-4 and Galphai.Synergistic regulation of glutamatergic transmission by serotonin and norepinephrine reuptake inhibitors in prefrontal cortical neurons.Regulation of the AGS3·G{alpha}i signaling complex by a seven-transmembrane span receptor.The effects of nucleus accumbens μ-opioid and adenosine 2A receptor stimulation and blockade on instrumental learning.Protein kinases and addiction.Implication of the purinergic system in alcohol use disorders.Presynaptic adenosine A2A receptors dampen cannabinoid CB1 receptor-mediated inhibition of corticostriatal glutamatergic transmissionReinforcing and neurochemical effects of cannabinoid CB1 receptor agonists, but not cocaine, are altered by an adenosine A2A receptor antagonist.Locomotor activity: A distinctive index in morphine self-administration in rats.Opiate-induced changes in brain adenosine levels and narcotic drug responses.Regulation of the G-protein regulatory-Gαi signaling complex by nonreceptor guanine nucleotide exchange factors.Adenosine transporter ENT1 regulates the acquisition of goal-directed behavior and ethanol drinking through A2A receptor in the dorsomedial striatum.Activator of G protein signaling 3 null mice: I. Unexpected alterations in metabolic and cardiovascular functionBehavioural and biochemical responses to morphine associated with its motivational properties are altered in adenosine A(2A) receptor knockout miceTranslocation of activator of G-protein signaling 3 to the Golgi apparatus in response to receptor activation and its effect on the trans-Golgi network.The pharmacology of the endocannabinoid system: functional and structural interactions with other neurotransmitter systems and their repercussions in behavioral addiction.Purinergic signaling and energy homeostasis in psychiatric disordersAdenosine signaling in striatal circuits and alcohol use disorders.Regulation of Chemokine Signal Integration by Activator of G-Protein Signaling 4 (AGS4).Disease-specific heteromerization of G-protein-coupled receptors that target drugs of abuseTuning and fine-tuning of synapses with adenosine.G-protein-coupled receptor heteromers as key players in the molecular architecture of the central nervous system.Crosstalk between dopamine D₂ receptors and cannabinoid CB₁ receptors regulates CNR1 promoter activity via ERK1/2 signaling.The role of nucleus accumbens adenosine-opioid interaction in mediating palatable food intake.Adenosine Receptor Stimulation by Polydeoxyribonucleotide Improves Tissue Repair and Symptomology in Experimental Colitis.Adenosine 2A receptors modulate reward behaviours for methamphetamine.
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P2860
Adenosine A2a blockade prevents synergy between mu-opiate and cannabinoid CB1 receptors and eliminates heroin-seeking behavior in addicted rats
description
2006 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի մայիսին հրատարակված գիտական հոդված
@hy
article publié dans les Procee ...... f the United States of America
@fr
artículu científicu espublizáu en 2006
@ast
im Mai 2006 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2006/05/16)
@sk
vědecký článek publikovaný v roce 2006
@cs
wetenschappelijk artikel (gepubliceerd op 2006/05/16)
@nl
наукова стаття, опублікована в травні 2006
@uk
name
Adenosine A2a blockade prevent ...... king behavior in addicted rats
@ast
Adenosine A2a blockade prevent ...... king behavior in addicted rats
@en
Adenosine A2a blockade prevent ...... king behavior in addicted rats
@nl
type
label
Adenosine A2a blockade prevent ...... king behavior in addicted rats
@ast
Adenosine A2a blockade prevent ...... king behavior in addicted rats
@en
Adenosine A2a blockade prevent ...... king behavior in addicted rats
@nl
prefLabel
Adenosine A2a blockade prevent ...... king behavior in addicted rats
@ast
Adenosine A2a blockade prevent ...... king behavior in addicted rats
@en
Adenosine A2a blockade prevent ...... king behavior in addicted rats
@nl
P2093
P2860
P921
P3181
P356
P1476
Adenosine A2a blockade prevent ...... king behavior in addicted rats
@en
P2093
Ivan Diamond
Krista McFarland
Peidong Fan
Takashi Ueda
Zhan Jiang
P2860
P304
P3181
P356
10.1073/PNAS.0602661103
P407
P577
2006-05-16T00:00:00Z