I1PP2A affects tau phosphorylation via association with the catalytic subunit of protein phosphatase 2A
about
Phosphatases of α-synuclein, LRRK2, and tau: important players in the phosphorylation-dependent pathology of ParkinsonismTargeted ANP32E mutant mice do not demonstrate obvious movement defectsStructural bases for recognition of Anp32/LANP proteinsMemantine Attenuates Alzheimer's Disease-Like Pathology and Cognitive ImpairmentCXCL12-mediated regulation of ANP32A/Lanp, a component of the inhibitor of histone acetyl transferase (INHAT) complex, in cortical neuronsUncovering molecular biomarkers that correlate cognitive decline with the changes of hippocampus' gene expression profiles in Alzheimer's disease.Knockdown of pp32 Increases Histone Acetylation and Ameliorates Cognitive Deficits.Relatively frequent switching of transcription start sites during cerebellar development.Mechanisms of tau-induced neurodegeneration.Cytoplasmic retention of protein phosphatase 2A inhibitor 2 (I2PP2A) induces Alzheimer-like abnormal hyperphosphorylation of Tau.Cracking the ANP32 whips: important functions, unequal requirement, and hints at disease implications.The carboxy-terminal fragment of inhibitor-2 of protein phosphatase-2A induces Alzheimer disease pathology and cognitive impairment.Study of Protein Phosphatase 2A (PP2A) Activity in LPS-Induced Tolerance Using Fluorescence-Based and Immunoprecipitation-Aided Methodology.Advances in the pathogenesis of Alzheimer's disease: focusing on tau-mediated neurodegeneration.GBA deficiency promotes SNCA/α-synuclein accumulation through autophagic inhibition by inactivated PPP2A.Protein carboxyl methylation and the biochemistry of memory.Further understanding of tau phosphorylation: implications for therapy.Intracellular and extracellular microtubule associated protein tau as a therapeutic target in Alzheimer disease and other tauopathies.GSK-3β is Dephosphorylated by PP2A in a Leu309 Methylation-Independent Manner.Microcystin-LR-caused ROS generation involved in p38 activation and tau hyperphosphorylation in neuroendocrine (PC12) cells.Tau as a biomarker of neurodegenerative diseases.Myeloid-Specific Gene Deletion of Protein Phosphatase 2A Magnifies MyD88- and TRIF-Dependent Inflammation following Endotoxin Challenge.The expression and distributions of ANP32A in the developing brain.Capping motifs stabilize the leucine-rich repeat protein PP32 and rigidify adjacent repeats.Tau Proteins and Tauopathies in Alzheimer's Disease.The new indirubin derivative inhibitors of glycogen synthase kinase-3, 6-BIDECO and 6-BIMYEO, prevent tau phosphorylation and apoptosis induced by the inhibition of protein phosphatase-2A by okadaic acid in cultured neurons.A novel function of Ataxin-1 in the modulation of PP2A activity is dysregulated in the spinocerebellar ataxia type 1.
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I1PP2A affects tau phosphorylation via association with the catalytic subunit of protein phosphatase 2A
description
2008 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
artículu científicu espublizáu en 2008
@ast
im April 2008 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2008/04/18)
@sk
vědecký článek publikovaný v roce 2008
@cs
wetenschappelijk artikel (gepubliceerd op 2008/04/18)
@nl
наукова стаття, опублікована у квітні 2008
@uk
name
I1PP2A affects tau phosphoryla ...... unit of protein phosphatase 2A
@ast
I1PP2A affects tau phosphoryla ...... unit of protein phosphatase 2A
@en
I1PP2A affects tau phosphoryla ...... unit of protein phosphatase 2A
@nl
type
label
I1PP2A affects tau phosphoryla ...... unit of protein phosphatase 2A
@ast
I1PP2A affects tau phosphoryla ...... unit of protein phosphatase 2A
@en
I1PP2A affects tau phosphoryla ...... unit of protein phosphatase 2A
@nl
prefLabel
I1PP2A affects tau phosphoryla ...... unit of protein phosphatase 2A
@ast
I1PP2A affects tau phosphoryla ...... unit of protein phosphatase 2A
@en
I1PP2A affects tau phosphoryla ...... unit of protein phosphatase 2A
@nl
P2093
P2860
P356
P1476
I1PP2A affects tau phosphoryla ...... unit of protein phosphatase 2A
@en
P2093
P2860
P304
10513–10521
P356
10.1074/JBC.M709852200
P407
P577
2008-04-18T00:00:00Z