ADP-ribosylation factor-dependent phospholipase D2 activation is required for agonist-induced mu-opioid receptor endocytosis
about
The Grb2/PLD2 interaction is essential for lipase activity, intracellular localization and signaling in response to EGFPhospholipase D2 localizes to the plasma membrane and regulates angiotensin II receptor endocytosisRole of phosphatidic acid in the coupling of the ERK cascade.Novel GPCR paradigms at the μ-opioid receptorA phosphatidylinositol-3-kinase-dependent signal transition regulates ARF1 and ARF6 during Fcgamma receptor-mediated phagocytosisADP-ribosylation factor-dependent phospholipase D activation by the M3 muscarinic receptorSelective interactions between helix VIII of the human mu-opioid receptors and the C terminus of periplakin disrupt G protein activationMembrane glycoprotein M6a interacts with the micro-opioid receptor and facilitates receptor endocytosis and recyclingRegulation of GPCR activity, trafficking and localization by GPCR-interacting proteins.Role of FK506 binding protein 12 in morphine-induced μ-opioid receptor internalization and desensitization.Phospholipase D signaling pathways and phosphatidic acid as therapeutic targets in cancerMembrane glycoprotein M6A promotes mu-opioid receptor endocytosis and facilitates receptor sorting into the recycling pathway.Functional selectivity at the μ-opioid receptor: implications for understanding opioid analgesia and tolerance.The exquisite regulation of PLD2 by a wealth of interacting proteins: S6K, Grb2, Sos, WASp and Rac2 (and a surprise discovery: PLD2 is a GEF).Phospholipase D: enzymology, functionality, and chemical modulationPhospholipase D in brain function and Alzheimer's disease.Mu-opioid receptor desensitization: is morphine different?Chronic morphine treatment up-regulates mu opioid receptor binding in cells lacking filamin A.Regulation of μ-opioid receptors: desensitization, phosphorylation, internalization, and tolerance.Phospholipase D signaling: orchestration by PIP2 and small GTPases.Cellular neuroadaptations to chronic opioids: tolerance, withdrawal and addiction.The potential for phospholipase D as a new therapeutic target.Molecular Pharmacology of δ-Opioid Receptors.Phospholipase D in platelets and other cells.Modulation of opioid receptor function by protein-protein interactions.Role of phospholipase D in parathyroid hormone type 1 receptor signaling and trafficking.Multifactorial Regulation of G Protein-Coupled Receptor Endocytosis.Regulation of aldosterone synthesis and secretion.Role of phospholipase d in g-protein coupled receptor functionInvolvement of Phospholipase D 1 and 2 in the subcellular localization and activity of formyl-peptide-receptors in the human colonic cell line HT29.mu-opioid receptor-stimulated synthesis of reactive oxygen species is mediated via phospholipase D2.Role of phospholipase D2 in the agonist-induced and constitutive endocytosis of G-protein coupled receptors.Effect of the A118G polymorphism on binding affinity, potency and agonist-mediated endocytosis, desensitization, and resensitization of the human mu-opioid receptor.Regulation of phospholipase D2 activity by protein kinase C alpha.Molecular mechanisms of N-formyl-methionyl-leucyl-phenylalanine-induced superoxide generation and degranulation in mouse neutrophils: phospholipase D is dispensable.Opioid agonists have different efficacy profiles for G protein activation, rapid desensitization, and endocytosis of mu-opioid receptors.Sustained Morphine Administration Induces TRPM8-Dependent Cold Hyperalgesia.Protein kinase D2: a versatile player in cancer biology.
P2860
Q24295239-8DF2B622-4C50-45E2-B4D2-BD0F37EB90E5Q24304439-B488261C-38C3-4D89-839A-0931CE555914Q24643389-676079A5-3200-43D4-84AD-057F3E2784A0Q26864286-A3C715BC-957C-47AE-914D-FFA95F2992FFQ27335399-FDBB8997-5E74-4501-9FB0-DCEEA97633B6Q28178279-6FAB98AF-1C00-47D7-9636-C6BE23B6831AQ28179746-DD08FCAB-9195-422A-8F32-15EBB94E3EB0Q28564599-BAF6A5AC-A211-4F14-81AF-AEDBDE445537Q30010478-6AFF881E-0F65-4612-B5AB-AF333EC2D09CQ33568279-17FA5DEA-B2D2-41BF-8C22-F85333EAEDA8Q34268347-01AD14CD-4BC0-4689-B4EA-FF8F6F61606AQ34788555-4B549D77-162E-4700-87D6-BEA59E9B24CBQ35264421-9B4C8BB5-66D7-4E25-8367-B5E9D53BD1BBQ35486098-34691CA9-134C-430B-AE69-3675D8441BCDQ35599714-C239B407-8DFC-4896-8AC9-1F0A2AC2B24EQ35893701-871200E5-F1BA-46F9-A744-D8CB05C78C53Q35927616-9692D287-223E-41EA-A9D4-811600CBE935Q36328175-25EAD3E2-5013-499F-B7B0-9428EDCAF317Q36591603-C5166FA3-CD49-46CB-BE69-4E297136A9B6Q36716517-33DD2DC8-5750-4522-B02D-6530FA8F0C78Q36741881-E7C2D2E8-6DAA-4EAB-90B3-505BE116211DQ36804452-4ADA7B0D-5969-4AB1-91EB-9856E99E2A38Q37062556-5274F6C2-2EC4-41D6-8C2E-64A69C04A21FQ37326638-08FCF557-6C62-423D-AA45-01D44A376DE0Q37410471-02974F28-F936-4C7E-B13E-15CBC92EDC59Q37484589-42D38826-C283-4E5B-88CD-FAFE01622965Q37551913-AF9424C9-7E73-4596-87B7-AC945D06EF37Q38221449-67B88F49-994D-45D6-AAAA-5B767F5E9355Q38226347-F2C3E57B-EAB3-4345-A612-F64516FB3996Q39808079-6FA63D15-45D7-45D6-81F5-82BA7AC238B5Q39839348-1B3989E3-B258-4BE0-8A35-33E8F70CC4FCQ40304496-CFA6BA8E-5B20-4218-82E5-EF286949F01DQ40566502-1005A269-A418-4D4B-B4A0-B0F326092C25Q42458821-A4347573-57B5-4B49-BFE1-8A83319C1285Q42531338-B99D3753-D375-4CCD-AFA1-0DC6366657F5Q44340828-130A5BCE-1A8A-4937-B109-3325E5A1AC96Q44914027-C36C5E37-1A67-4563-AD08-EA0FD0E8D94CQ47273020-07D1C2B8-F8A9-4030-900F-12B45A48BEF8
P2860
ADP-ribosylation factor-dependent phospholipase D2 activation is required for agonist-induced mu-opioid receptor endocytosis
description
2003 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի մարտին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
artículu científicu espublizáu en 2003
@ast
im März 2003 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2003/03/14)
@sk
vědecký článek publikovaný v roce 2003
@cs
wetenschappelijk artikel (gepubliceerd op 2003/03/14)
@nl
наукова стаття, опублікована в березні 2003
@uk
name
ADP-ribosylation factor-depend ...... mu-opioid receptor endocytosis
@ast
ADP-ribosylation factor-depend ...... mu-opioid receptor endocytosis
@en
ADP-ribosylation factor-depend ...... mu-opioid receptor endocytosis
@nl
type
label
ADP-ribosylation factor-depend ...... mu-opioid receptor endocytosis
@ast
ADP-ribosylation factor-depend ...... mu-opioid receptor endocytosis
@en
ADP-ribosylation factor-depend ...... mu-opioid receptor endocytosis
@nl
prefLabel
ADP-ribosylation factor-depend ...... mu-opioid receptor endocytosis
@ast
ADP-ribosylation factor-depend ...... mu-opioid receptor endocytosis
@en
ADP-ribosylation factor-depend ...... mu-opioid receptor endocytosis
@nl
P2093
P2860
P356
P1476
ADP-ribosylation factor-depend ...... mu-opioid receptor endocytosis
@en
P2093
Jochen Klein
Lars-Ove Brandenburg
Thomas Koch
Volker Hollt
Yingjian Liang
P2860
P304
P356
10.1074/JBC.M206709200
P407
P577
2003-03-14T00:00:00Z