Increased cytochrome P-450 2E1 expression sensitizes hepatocytes to c-Jun-mediated cell death from TNF-alpha
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Potential Role of the Gut/Liver/Lung Axis in Alcohol-Induced Tissue PathologyCritical Roles of Kupffer Cells in the Pathogenesis of Alcoholic Liver Disease: From Basic Science to Clinical TrialsCYP2E1 potentiation of LPS and TNFα-induced hepatotoxicity by mechanisms involving enhanced oxidative and nitrosative stress, activation of MAP kinases, and mitochondrial dysfunction.Activation of ASK-1 and downstream MAP kinases in cytochrome P4502E1 potentiated tumor necrosis factor alpha liver injuryChronic ethanol feeding potentiates Fas Jo2-induced hepatotoxicity: role of CYP2E1 and TNF-alpha and activation of JNK and P38 MAP kinase.Chronic alcohol-induced liver injury and oxidant stress are decreased in cytochrome P4502E1 knockout mice and restored in humanized cytochrome P4502E1 knock-in mice.JNK regulation of hepatic manifestations of the metabolic syndrome.Regulation of the effects of CYP2E1-induced oxidative stress by JNK signaling.Liver proteomics in progressive alcoholic steatosis.Hepatotoxicity mediated by pyrazole (cytochrome P450 2E1) plus tumor necrosis factor alpha treatment occurs in c-Jun N-terminal kinase 2-/- but not in c-Jun N-terminal kinase 1-/- mice.Role of CYP2E1 in ethanol-induced oxidant stress, fatty liver and hepatotoxicity.Early-phase alcoholic liver disease: an update on animal models, pathology, and pathogenesis.Mitogen-activated protein kinase phosphatase (Mkp)-1 protects mice against acetaminophen-induced hepatic injury.CYP2E1 and oxidative liver injury by alcohol.Protein targets of reactive metabolites of thiobenzamide in rat liver in vivoCHIP(-/-)-Mouse Liver: Adiponectin-AMPK-FOXO-Activation Overrides CYP2E1-Elicited JNK1-Activation, Delaying Onset of NASH: Therapeutic Implications.Inhibition of the mitochondrial permeability transition by cyclosporin A prevents pyrazole plus lipopolysaccharide-induced liver injury in mice.Mechanisms and cell signaling in alcoholic liver disease.Alcoholic liver disease and the potential role of plasminogen activator inhibitor-1 and fibrin metabolism.Inhibition of autophagy promotes CYP2E1-dependent toxicity in HepG2 cells via elevated oxidative stress, mitochondria dysfunction and activation of p38 and JNK MAPK.Chronic oxidative stress sensitizes hepatocytes to death from 4-hydroxynonenal by JNK/c-Jun overactivation.Role of oxidative stress in alcohol-induced liver injury.CYP2E1 Sensitizes the Liver to LPS- and TNF α-Induced Toxicity via Elevated Oxidative and Nitrosative Stress and Activation of ASK-1 and JNK Mitogen-Activated Kinases.Proapoptotic function of protein kinase CK2alpha" is mediated by a JNK signaling cascade.The future of GI and liver research: editorial perspectives. III. JNK/AP-1 regulation of hepatocyte death.Critical role of c-jun (NH2) terminal kinase in paracetamol- induced acute liver failure.TLRs, Alcohol, HCV, and Tumorigenesis.Qushi Huayu Decoction (祛湿化瘀方) inhibits protein and gene expression of cathepsin B in HepG2 cells induced by free fatty acids.Cytochrome P4502E1 primes macrophages to increase TNF-alpha production in response to lipopolysaccharide.Cytochrome P4502E1 sensitizes to tumor necrosis factor alpha-induced liver injury through activation of mitogen-activated protein kinases in mice.Liver injury in the setting of steatosis: crosstalk between adipokine and cytokine.
P2860
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P2860
Increased cytochrome P-450 2E1 expression sensitizes hepatocytes to c-Jun-mediated cell death from TNF-alpha
description
2002 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2002
@ast
scientific journal article
@en
vedecký článok (publikovaný 2002/02/01)
@sk
vědecký článek publikovaný v roce 2002
@cs
wetenschappelijk artikel (gepubliceerd op 2002/02/01)
@nl
наукова стаття, опублікована в лютому 2002
@uk
مقالة علمية (نشرت في فبراير 2002)
@ar
name
Increased cytochrome P-450 2E1 ...... ated cell death from TNF-alpha
@ast
Increased cytochrome P-450 2E1 ...... ated cell death from TNF-alpha
@en
Increased cytochrome P-450 2E1 ...... ated cell death from TNF-alpha
@nl
type
label
Increased cytochrome P-450 2E1 ...... ated cell death from TNF-alpha
@ast
Increased cytochrome P-450 2E1 ...... ated cell death from TNF-alpha
@en
Increased cytochrome P-450 2E1 ...... ated cell death from TNF-alpha
@nl
prefLabel
Increased cytochrome P-450 2E1 ...... ated cell death from TNF-alpha
@ast
Increased cytochrome P-450 2E1 ...... ated cell death from TNF-alpha
@en
Increased cytochrome P-450 2E1 ...... ated cell death from TNF-alpha
@nl
P2093
P2860
P3181
P356
P1476
Increased cytochrome P-450 2E1 ...... ated cell death from TNF-alpha
@en
P2093
Brett E. Jones
Cynthia Bradham
Hailing Liu
Mark J. Czaja
P2860
P304
P3181
P356
10.1152/AJPGI.00304.2001
P577
2002-02-01T00:00:00Z