Functional characterization of a mammalian Sac1 and mutants exhibiting substrate-specific defects in phosphoinositide phosphatase activity - Wikidata - awgldk - TriplyDB

Functional characterization of a mammalian Sac1 and mutants exhibiting substrate-specific defects in phosphoinositide phosphatase activity

Functional characterization of a mammalian Sac1 and mutants exhibiting substrate-specific defects in phosphoinositide phosphatase activity

http://www.wikidata.org/entity/Q28567201

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Integral and associated lysosomal membrane proteins The human phosphatidylinositol phosphatase SAC1 interacts with the coatomer I complex Core protein machinery for mammalian phosphatidylinositol 3,5-bisphosphate synthesis and turnover that regulates the progression of endosomal transport. Novel Sac phosphatase joins the ArPIKfyve-PIKfyve complex INTRACELLULAR TRANSPORT. PI4P/phosphatidylserine countertransport at ORP5- and ORP8-mediated ER-plasma membrane contacts Localization of a highly active pool of type II phosphatidylinositol 4-kinase in a p97/valosin-containing-protein-rich fraction of the endoplasmic reticulum The SAC domain-containing protein gene family in Arabidopsis Identification of mitogen-activated protein kinase docking sites in enzymes that metabolize phosphatidylinositols and inositol phosphates.Phosphoinositides: tiny lipids with giant impact on cell regulation Golgi membrane dynamics and lipid metabolism Dynamic formation of ER-PM junctions presents a lipid phosphatase to regulate phosphoinositides PtdIns4 P recognition by Vps74/GOLPH3 links PtdIns 4-kinase signaling to retrograde Golgi trafficking Crystal structure of the yeast Sac1: implications for its phosphoinositide phosphatase function Resurrection of a functional phosphatidylinositol transfer protein from a pseudo-Sec14 scaffold by directed evolution Sac1 lipid phosphatase and Stt4 phosphatidylinositol 4-kinase regulate a pool of phosphatidylinositol 4-phosphate that functions in the control of the actin cytoskeleton and vacuole morphology.Allosteric activation of the phosphoinositide phosphatase Sac1 by anionic phospholipids.Retention of the yeast Sac1p phosphatase in the endoplasmic reticulum causes distinct changes in cellular phosphoinositide levels and stimulates microsomal ATP transport.Analysis of oxysterol binding protein homologue Kes1p function in regulation of Sec14p-dependent protein transport from the yeast Golgi complex.Identification and characterization of a sac domain-containing phosphoinositide 5-phosphatase Sac2/INPP5F is an inositol 4-phosphatase that functions in the endocytic pathway.Spatiotemporal control of phosphatidylinositol 4-phosphate by Sac2 regulates endocytic recycling Identification and characterization of a synaptojanin 2 splice isoform predominantly expressed in nerve terminals rSac3, a novel Sac domain phosphoinositide phosphatase, promotes neurite outgrowth in PC12 cells The Sac1 phosphoinositide phosphatase regulates Golgi membrane morphology and mitotic spindle organization in mammals.A novel probe for phosphatidylinositol 4-phosphate reveals multiple pools beyond the Golgi.The Sac domain-containing phosphoinositide phosphatases: structure, function, and disease Phosphoinositide phosphatases in cell biology and disease.Functional studies of the mammalian Sac1 phosphoinositide phosphatase Zebrafish class 1 phosphatidylinositol transfer proteins: PITPbeta and double cone cell outer segment integrity in retina.The structure of phosphoinositide phosphatases: Insights into substrate specificity and catalysis.Biological functions of phosphatidylinositol transfer proteins.Organelle identity and the organization of membrane traffic.Phosphoinositides and vesicular membrane traffic The Sec14-superfamily and the regulatory interface between phospholipid metabolism and membrane trafficking Phosphatidylinositol transfer proteins and functional specification of lipid signaling pools.An enzymatic cascade of Rab5 effectors regulates phosphoinositide turnover in the endocytic pathway.Synthesis and function of membrane phosphoinositides in budding yeast, Saccharomyces cerevisiae Increased levels of phosphoinositides cause neurodegeneration in a Drosophila model of amyotrophic lateral sclerosis SAC1 lipid phosphatase and growth control of the secretory pathway.The phosphoinositide phosphatase Sac1 is required for midline axon guidance.Regulation of Golgi function via phosphoinositide lipids.

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Functional characterization of a mammalian Sac1 and mutants exhibiting substrate-specific defects in phosphoinositide phosphatase activity

http://www.wikidata.org/entity/Q28567201

description

2000 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

@hyw

2000 թվականի նոյեմբերին հրատարակված գիտական հոդված

@hy

article publié dans la revue scientifique Journal of Biological Chemistry

@fr

artículu científicu espublizáu en 2000

@ast

im November 2000 veröffentlichter wissenschaftlicher Artikel

@de

scientific journal article

@en

vedecký článok (publikovaný 2000/11/03)

@sk

vědecký článek publikovaný v roce 2000

@cs

wetenschappelijk artikel (gepubliceerd op 2000/11/03)

@nl

наукова стаття, опублікована в листопаді 2000

@uk

name

Functional characterization of ...... inositide phosphatase activity

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Functional characterization of ...... inositide phosphatase activity

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Functional characterization of ...... inositide phosphatase activity

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Functional characterization of ...... inositide phosphatase activity

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Functional characterization of ...... inositide phosphatase activity

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Functional characterization of ...... inositide phosphatase activity

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Functional characterization of ...... inositide phosphatase activity

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Functional characterization of ...... inositide phosphatase activity

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Functional characterization of ...... inositide phosphatase activity

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Journal of Biological Chemistry

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Functional characterization of ...... inositide phosphatase activity

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P2093

B. G. Kearns

http://www.w3.org/2001/XMLSchema#string

H. Chen

http://www.w3.org/2001/XMLSchema#string

J. G. Alb

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K. Mori

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M. R. Wenk

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P. De Camilli

http://www.w3.org/2001/XMLSchema#string

V. A. Bankaitis

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Y. Nemoto

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P2860

DNA sequencing with chain-terminating inhibitors

The Lowe's oculocerebrorenal syndrome gene encodes a protein highly homologous to inositol polyphosphate-5-phosphatase

Pheromone-regulated genes required for yeast mating differentiation

A simple method for displaying the hydropathic character of a protein

Isolation of monoclonal antibodies specific for human c-myc proto-oncogene product

SAC1 encodes a regulated lipid phosphoinositide phosphatase, defects in which can be suppressed by the homologous Inp52p and Inp53p phosphatases.

Identification of 23 complementation groups required for post-translational events in the yeast secretory pathway.

The yeast phosphatidylinositol-4-OH kinase pik1 regulates secretion at the Golgi.

Pleiotropic alterations in lipid metabolism in yeast sac1 mutants: relationship to "bypass Sec14p" and inositol auxotrophy.

SAC1-like domains of yeast SAC1, INP52, and INP53 and of human synaptojanin encode polyphosphoinositide phosphatases.

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34293–34305

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scholarly article

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4914132

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P356

10.1074/JBC.M003923200

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P433

44

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275

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2000-11-03T00:00:00Z

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P698

10887188

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