Imatinib mesylate blocks a non-Smad TGF-beta pathway and reduces renal fibrogenesis in vivo
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Galectin-3 regulates myofibroblast activation and hepatic fibrosisNew Insight into the Anti-liver Fibrosis Effect of Multitargeted Tyrosine Kinase Inhibitors: From Molecular Target to Clinical TrialsPlatelet-derived growth factors (PDGFs) in glomerular and tubulointerstitial fibrosisKey Fibrogenic SignalingP21-activated kinase-2 is a critical mediator of transforming growth factor-β-induced hepatoma cell migrationNoncanonical TGF-beta pathways, mTORC1 and Abl, in renal interstitial fibrogenesisNf1+/- mast cells induce neurofibroma like phenotypes through secreted TGF-beta signalingNon-Smad pathways in TGF-beta signalingMolecular mechanisms for Alzheimer's disease: implications for neuroimaging and therapeutics.The role of proteomics in dementia and Alzheimer's disease.A non-Smad mechanism of fibroblast activation by transforming growth factor-beta via c-Abl and Egr-1: selective modulation by imatinib mesylate.Activated Abl kinase inhibits oncogenic transforming growth factor-beta signaling and tumorigenesis in mammary tumors.Mechanisms of the epithelial-mesenchymal transition by TGF-betaLate-onset dementia: a mosaic of prototypical pathologies modifiable by diet and lifestyle.Galvanotactic migration of EA.Hy926 endothelial cells in a novel designed electric field bioreactor.Tyrosine kinases in inflammatory dermatologic disease.Mitochondrial dysfunction and cellular metabolic deficiency in Alzheimer's diseaseInvolvement of oxidative stress in Alzheimer disease.Screening candidate longevity therapeutics using gene-expression arrays.Sirtuins in aging and disease.Signal transduction pathway analysis in fibromatosis: receptor and nonreceptor tyrosine kinases.Platelet-derived serotonin links vascular disease and tissue fibrosis.Tyrosine kinases inhibition by Imatinib slows progression in chronic anti-thy1 glomerulosclerosis of the ratBlockade of PDGF receptor signaling reduces myofibroblast number and attenuates renal fibrosis.Platelet-derived growth factor receptor-β and epidermal growth factor receptor in pulmonary vasculature of systemic sclerosis-associated pulmonary arterial hypertension versus idiopathic pulmonary arterial hypertension and pulmonary veno-occlusive dEarly growth response transcription factors: key mediators of fibrosis and novel targets for anti-fibrotic therapy.Platelet-derived growth factor-beta receptor activation is essential for fibroblast and pericyte recruitment during cutaneous wound healing.c-Abl silencing reduced the inhibitory effects of TGF-β1 on apoptosis in systemic sclerosis dermal fibroblasts.Mitochondrial medicine for aging and neurodegenerative diseasesThe Cain and Abl of epithelial-mesenchymal transition and transforming growth factor-β in mammary epithelial cellsSirtuins in neurodegenerative diseases: a biological-chemical perspective.Inhibiting ERK Activation with CI-1040 Leads to Compensatory Upregulation of Alternate MAPKs and Plasminogen Activator Inhibitor-1 following Subtotal Nephrectomy with No Impact on Kidney Fibrosis.Proteomic analysis of neurons microdissected from formalin-fixed, paraffin-embedded Alzheimer's disease brain tissueNetwork-Based Analysis of Nutraceuticals in Human Hepatocellular Carcinomas Reveals Mechanisms of Chemopreventive ActionSmad3 Signaling Promotes Fibrosis While Preserving Cardiac and Aortic Geometry in Obese Diabetic Mice.p21-Activated kinase 2 (PAK2) inhibits TGF-β signaling in Madin-Darby canine kidney (MDCK) epithelial cells by interfering with the receptor-Smad interactionSleep disturbances in Alzheimer's and Parkinson's diseases.Systems biology approaches to study the molecular effects of caloric restriction and polyphenols on aging processes.Imatinib attenuates cardiac fibrosis by inhibiting platelet-derived growth factor receptors activation in isoproterenol induced model.Poly(I:C) increases the expression of mPGES-1 and COX-2 in rat primary microglia
P2860
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P2860
Imatinib mesylate blocks a non-Smad TGF-beta pathway and reduces renal fibrogenesis in vivo
description
2005 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի հունվարին հրատարակված գիտական հոդված
@hy
artikull shkencor
@sq
artículu científicu espublizáu en 2005
@ast
im Januar 2005 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
wetenschappelijk artikel
@nl
наукова стаття, опублікована в січні 2005
@uk
مقالة علمية (نشرت عام 2005)
@ar
name
Imatinib mesylate blocks a non ...... ces renal fibrogenesis in vivo
@ast
Imatinib mesylate blocks a non ...... ces renal fibrogenesis in vivo
@en
Imatinib mesylate blocks a non ...... ces renal fibrogenesis in vivo
@nl
type
label
Imatinib mesylate blocks a non ...... ces renal fibrogenesis in vivo
@ast
Imatinib mesylate blocks a non ...... ces renal fibrogenesis in vivo
@en
Imatinib mesylate blocks a non ...... ces renal fibrogenesis in vivo
@nl
prefLabel
Imatinib mesylate blocks a non ...... ces renal fibrogenesis in vivo
@ast
Imatinib mesylate blocks a non ...... ces renal fibrogenesis in vivo
@en
Imatinib mesylate blocks a non ...... ces renal fibrogenesis in vivo
@nl
P2093
P356
P1433
P1476
Imatinib mesylate blocks a non ...... ces renal fibrogenesis in vivo
@en
P2093
Edward B. Leof
Mark C. Wilkes
Raimund Hirschberg
Shinong Wang
P356
10.1096/FJ.04-2370COM
P407
P577
2005-01-01T00:00:00Z