Misfolding of proteins with a polyglutamine expansion is facilitated by proteasomal chaperones
about
The DNAJB6 and DNAJB8 protein chaperones prevent intracellular aggregation of polyglutamine peptidesThe life cycle of the 26S proteasome: from birth, through regulation and function, and onto its deathExposure of hydrophobic surfaces initiates aggregation of diverse ALS-causing superoxide dismutase-1 mutants.Widespread Proteome Remodeling and Aggregation in Aging C. elegans.Molecular chaperones antagonize proteotoxicity by differentially modulating protein aggregation pathways.Reduced Levels of Proteasome Products in a Mouse Striatal Cell Model of Huntington's Disease.Paradoxical resistance of multiple myeloma to proteasome inhibitors by decreased levels of 19S proteasomal subunits.Spatial control of Shoc2-scaffold-mediated ERK1/2 signaling requires remodeling activity of the ATPase PSMC5.Expanded polyglutamine-containing N-terminal huntingtin fragments are entirely degraded by mammalian proteasomes.Generalization of the prion hypothesis to other neurodegenerative diseases: an imperfect fit.Evolutionary selection for protein aggregation.The Autophagoproteasome a Novel Cell Clearing Organelle in Baseline and Stimulated Conditions.Dynamic recruitment of active proteasomes into polyglutamine initiated inclusion bodies.The Aggregation of Huntingtin and α-Synuclein.The Ubiquitin-Proteasome System in Huntington's Disease: Are Proteasomes Impaired, Initiators of Disease, or Coming to the Rescue?Essential role of coiled coils for aggregation and activity of Q/N-rich prions and PolyQ proteins.A role for the proteasome in the turnover of Sup35p and in [PSI(+) ] prion propagation.
P2860
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P2860
Misfolding of proteins with a polyglutamine expansion is facilitated by proteasomal chaperones
description
2009 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հունվարին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
artículu científicu espublizáu en 2009
@ast
im Januar 2009 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2009/01/16)
@sk
vědecký článek publikovaný v roce 2009
@cs
wetenschappelijk artikel (gepubliceerd op 2009/01/16)
@nl
наукова стаття, опублікована в січні 2009
@uk
name
Misfolding of proteins with a ...... ated by proteasomal chaperones
@ast
Misfolding of proteins with a ...... ated by proteasomal chaperones
@en
Misfolding of proteins with a ...... ated by proteasomal chaperones
@nl
type
label
Misfolding of proteins with a ...... ated by proteasomal chaperones
@ast
Misfolding of proteins with a ...... ated by proteasomal chaperones
@en
Misfolding of proteins with a ...... ated by proteasomal chaperones
@nl
prefLabel
Misfolding of proteins with a ...... ated by proteasomal chaperones
@ast
Misfolding of proteins with a ...... ated by proteasomal chaperones
@en
Misfolding of proteins with a ...... ated by proteasomal chaperones
@nl
P2093
P2860
P3181
P356
P1476
Misfolding of proteins with a ...... ated by proteasomal chaperones
@en
P2093
Erwann Rousseau
Guylaine Hoffner
Philippe Djian
Rieko Kojima
P2860
P304
P3181
P356
10.1074/JBC.M806256200
P407
P577
2009-01-16T00:00:00Z