GADD34 mediates cytoprotective autophagy in mutant huntingtin expressing cells via the mTOR pathway
about
Cutting through the complexities of mTOR for the treatment of strokeShedding new light on neurodegenerative diseases through the mammalian target of rapamycinDriving neural regeneration through the mammalian target of rapamycinLimited ATF4 Expression in Degenerating Retinas with Ongoing ER Stress Promotes Photoreceptor Survival in a Mouse Model of Autosomal Dominant Retinitis PigmentosaTaking aim at Alzheimer's disease through the mammalian target of rapamycinHydrogen sulfide protects spinal cord and induces autophagy via miR-30c in a rat model of spinal cord ischemia-reperfusion injury.GADD34 Keeps the mTOR Pathway Inactivated in Endoplasmic Reticulum Stress Related Autophagy.A Critical Kinase Cascade in Neurological Disorders: PI 3-K, Akt, and mTOR.Oxidant stress and signal transduction in the nervous system with the PI 3-K, Akt, and mTOR cascadeNovel directions for diabetes mellitus drug discoverymTOR: on target for novel therapeutic strategies in the nervous system.Salubrinal-Mediated Upregulation of eIF2α Phosphorylation Increases Doxorubicin Sensitivity in MCF-7/ADR Cells.Mapping the crossroads of immune activation and cellular stress response pathways.mTOR in Brain Physiology and Pathologies.Moving to the Rhythm with Clock (Circadian) Genes, Autophagy, mTOR, and SIRT1 in Degenerative Disease and Cancer.GADD34 inhibits activation-induced apoptosis of macrophages through enhancement of autophagy.Induction of GADD34 Regulates the Neurotoxicity of Amyloid β.Sigma-1 receptor agonist PRE084 is protective against mutant huntingtin-induced cell degeneration: involvement of calpastatin and the NF-κB pathway.Synthetic lethal interactions in yeast reveal functional roles of J protein co-chaperonesmTOR inhibition increases cell viability via autophagy induction during endoplasmic reticulum stress - An experimental and modeling study.Ubiquitin-specific protease-14 reduces cellular aggregates and protects against mutant huntingtin-induced cell degeneration: involvement of the proteasome and ER stress-activated kinase IRE1α.Novel Treatment Strategies for the Nervous System: Circadian Clock Genes, Non-coding RNAs, and Forkhead Transcription Factors.The mechanistic target of rapamycin (mTOR) and the silent mating-type information regulation 2 homolog 1 (SIRT1): oversight for neurodegenerative disorders.Epigallocatechin-3-Gallate (EGCG) Promotes Autophagy-Dependent Survival via Influencing the Balance of mTOR-AMPK Pathways upon Endoplasmic Reticulum Stress.
P2860
Q26851291-5F80DA2D-567B-4AB5-837C-FF59EBC0EA49Q27015640-054F5B10-B5CA-4DB2-8F7F-4DA6BFA7EDA7Q27027516-6621D702-9CDF-4793-8829-2BD674E4CE90Q27348512-DB7C5EBE-5EE1-4541-8273-D5FC10DFE271Q34603651-2CDBD5F2-D0B5-4F8A-AD4D-63EFAB6231F3Q35819303-9235B866-A120-40EB-B755-18F34728446AQ36228566-572BD4AD-D57A-4800-A283-74B8B825644EQ36379761-1C557A4B-7312-4453-A895-FFF9A8326AE3Q36432388-B1388E4F-F9F1-4BC6-B373-38DDF652E3B8Q36487424-E6A2DCD7-4348-49FD-A466-DCAEFFBF77E2Q36501214-441BF2A3-C0FB-4FF0-936F-4F03058D2B01Q36591295-D916FF1A-EE81-4056-B5E2-55B4748568D8Q38098884-0A27E360-8F4E-4FC7-885C-0F537FBF85F0Q38565769-9FCDD0AF-60C3-4459-A047-BE53086D17A8Q38655453-EB5F3F32-B537-4C35-91A4-7F0B137FB195Q38912131-249D4ECE-B321-443B-AE6D-380E3A0E74C1Q38958138-18C71443-9C71-4940-A40D-8DB3D0FF83C5Q39148056-8734DB99-FBDB-479F-ADFD-A36424873471Q41903367-0F140011-569F-4449-8B13-020B6F87B3C2Q42026236-8FD067EC-0375-4DA7-BBB3-E4B479256B11Q45299812-DECC4FFE-248F-47C3-921C-2E82E22A690CQ51761339-906C16BE-6D90-4D09-BDF7-BB8A55E56E49Q52361076-53013F23-6E5B-4475-8A84-420B1EA1B16DQ52595123-6896CB13-0B19-4DA3-B625-FB2D16A8E930
P2860
GADD34 mediates cytoprotective autophagy in mutant huntingtin expressing cells via the mTOR pathway
description
2012 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի հունվարին հրատարակված գիտական հոդված
@hy
artikull shkencor
@sq
artículu científicu espublizáu en 2012
@ast
im Januar 2012 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
wetenschappelijk artikel
@nl
наукова стаття, опублікована в січні 2012
@uk
مقالة علمية (نشرت عام 2012)
@ar
name
GADD34 mediates cytoprotective ...... ing cells via the mTOR pathway
@ast
GADD34 mediates cytoprotective ...... ing cells via the mTOR pathway
@en
GADD34 mediates cytoprotective ...... ing cells via the mTOR pathway
@nl
type
label
GADD34 mediates cytoprotective ...... ing cells via the mTOR pathway
@ast
GADD34 mediates cytoprotective ...... ing cells via the mTOR pathway
@en
GADD34 mediates cytoprotective ...... ing cells via the mTOR pathway
@nl
prefLabel
GADD34 mediates cytoprotective ...... ing cells via the mTOR pathway
@ast
GADD34 mediates cytoprotective ...... ing cells via the mTOR pathway
@en
GADD34 mediates cytoprotective ...... ing cells via the mTOR pathway
@nl
P2093
P3181
P1476
GADD34 mediates cytoprotective ...... ing cells via the mTOR pathway
@en
P2093
Alise Hyrskyluoto
Dan Lindholm
Jenny Kivinen
Laura Korhonen
Sami Reijonen
P3181
P356
10.1016/J.YEXCR.2011.08.020
P407
P577
2012-01-01T00:00:00Z