Dominant-negative alpha-subunit of farnesyl- and geranyltransferase inhibits glucose-stimulated, but not KCl-stimulated, insulin secretion in INS 832/13 cells
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Regulation of glucose- and mitochondrial fuel-induced insulin secretion by a cytosolic protein histidine phosphatase in pancreatic beta-cellsFeasibility of pathways for transfer of acyl groups from mitochondria to the cytosol to form short chain acyl-CoAs in the pancreatic beta cellRegulatory roles for Tiam1, a guanine nucleotide exchange factor for Rac1, in glucose-stimulated insulin secretion in pancreatic beta-cellsGlucose activates prenyltransferases in pancreatic islet beta-cells.YES, a Src family kinase, is a proximal glucose-specific activator of cell division cycle control protein 42 (Cdc42) in pancreatic islet β cellsProtein farnesylation-dependent Raf/extracellular signal-related kinase signaling links to cytoskeletal remodeling to facilitate glucose-induced insulin secretion in pancreatic beta-cells.Small G proteins in islet beta-cell function.Phagocyte-like NADPH oxidase promotes cytokine-induced mitochondrial dysfunction in pancreatic β-cells: evidence for regulation by Rac1.Phagocyte-like NADPH oxidase generates ROS in INS 832/13 cells and rat islets: role of protein prenylation.Protein prenylation in glucose-induced insulin secretion from the pancreatic islet beta cell: a perspective.Friendly, and not so friendly, roles of Rac1 in islet β-cell function: lessons learnt from pharmacological and molecular biological approachesA farnesylated G-protein suppresses Akt phosphorylation in INS 832/13 cells and normal rat islets: regulation by pertussis toxin and PGE₂.Isoprenylcysteine carboxyl methyltransferase facilitates glucose-induced Rac1 activation, ROS generation and insulin secretion in INS 832/13 β-cells.EHT 1864, a small molecule inhibitor of Ras-related C3 botulinum toxin substrate 1 (Rac1), attenuates glucose-stimulated insulin secretion in pancreatic β-cells.Tiam1-Rac1 Axis Promotes Activation of p38 MAP Kinase in the Development of Diabetic Retinopathy: Evidence for a Requisite Role for Protein PalmitoylationEmerging roles for protein histidine phosphorylation in cellular signal transduction: lessons from the islet beta-cell.VAV2, a guanine nucleotide exchange factor for Rac1, regulates glucose-stimulated insulin secretion in pancreatic beta cells.Rac-mediated actin remodeling and myosin II are involved in KATP channel trafficking in pancreatic β-cells.Ras-related C3 botulinum toxin substrate 1 (RAC1) regulates glucose-stimulated insulin secretion via modulation of F-actin.A novel histone deacetylase inhibitor prevents IL-1beta induced metabolic dysfunction in pancreatic beta-cells.Regulatory roles for histone deacetylation in IL-1beta-induced nitric oxide release in pancreatic beta-cells.Exposure to chronic hyperglycemic conditions results in Ras-related C3 botulinum toxin substrate 1 (Rac1)-mediated activation of p53 and ATM kinase in pancreatic β-cells.Tiam1/Vav2-Rac1 axis: A tug-of-war between islet function and dysfunction.Rab-geranylgeranyl transferase regulates glucose-stimulated insulin secretion from pancreatic β cells.Nifedipine prevents etoposide-induced caspase-3 activation, prenyl transferase degradation and loss in cell viability in pancreatic β-cells.Exploring the putative self-binding property of the human farnesyltransferase alpha-subunit.TIAM1-RAC1 signalling axis-mediated activation of NADPH oxidase-2 initiates mitochondrial damage in the development of diabetic retinopathy.Role of G-proteins in islet function in health and diabetes.
P2860
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P2860
Dominant-negative alpha-subunit of farnesyl- and geranyltransferase inhibits glucose-stimulated, but not KCl-stimulated, insulin secretion in INS 832/13 cells
description
2007 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի հունվարին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2007
@ast
im Januar 2007 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2007/01/01)
@sk
vědecký článek publikovaný v roce 2007
@cs
wetenschappelijk artikel (gepubliceerd op 2007/01/01)
@nl
наукова стаття, опублікована в січні 2007
@uk
مقالة علمية (نشرت عام 2007)
@ar
name
Dominant-negative alpha-subuni ...... secretion in INS 832/13 cells
@ast
Dominant-negative alpha-subuni ...... secretion in INS 832/13 cells
@en
Dominant-negative alpha-subuni ...... secretion in INS 832/13 cells
@nl
type
label
Dominant-negative alpha-subuni ...... secretion in INS 832/13 cells
@ast
Dominant-negative alpha-subuni ...... secretion in INS 832/13 cells
@en
Dominant-negative alpha-subuni ...... secretion in INS 832/13 cells
@nl
prefLabel
Dominant-negative alpha-subuni ...... secretion in INS 832/13 cells
@ast
Dominant-negative alpha-subuni ...... secretion in INS 832/13 cells
@en
Dominant-negative alpha-subuni ...... secretion in INS 832/13 cells
@nl
P2093
P356
P1433
P1476
Dominant-negative alpha-subuni ...... secretion in INS 832/13 cells
@en
P2093
Hitchintan Kaur
Marc Goalstone
Rajakrishnan Veluthakal
P304
P356
10.2337/DB06-0668
P407
P577
2007-01-01T00:00:00Z