Activation of peroxisome proliferator-activated receptor alpha increases the expression and activity of microsomal triglyceride transfer protein in the liver
about
The blind men 'see' the elephant-the many faces of fatty liver diseaseApolipoprotein B: a clinically important apolipoprotein which assembles atherogenic lipoproteins and promotes the development of atherosclerosisFoxO1 mediates insulin-dependent regulation of hepatic VLDL production in miceNonalcoholic hepatic steatosis in Zucker diabetic rats: spontaneous evolution and effects of metformin and fenofibrateClofibrate causes an upregulation of PPAR-{alpha} target genes but does not alter expression of SREBP target genes in liver and adipose tissue of pigs.Evolutionary conservation of drug action on lipoprotein metabolism-related targets.HIV-1 Vpr induces adipose dysfunction in vivo through reciprocal effects on PPAR/GR co-regulation.PPAR/RXR Regulation of Fatty Acid Metabolism and Fatty Acid omega-Hydroxylase (CYP4) Isozymes: Implications for Prevention of Lipotoxicity in Fatty Liver DiseaseAn intrinsic gut leptin-melanocortin pathway modulates intestinal microsomal triglyceride transfer protein and lipid absorptionTranscriptomic signatures of peroxisome proliferator-activated receptor α (PPARα) in different mouse liver models identify novel aspects of its biology.Hepatic Cerebroside Sulfotransferase Is Induced by PPARα Activation in MicePlasticizers May Activate Human Hepatic Peroxisome Proliferator-Activated Receptor α Less Than That of a Mouse but May Activate Constitutive Androstane Receptor in LiverEffects of insulin resistance and hepatic lipid accumulation on hepatic mRNA expression levels of apoB, MTP and L-FABP in non-alcoholic fatty liver disease.MTP regulated by an alternate promoter is essential for NKT cell development.Alcohol and lipid metabolism.ApoB100 is required for increased VLDL-triglyceride secretion by microsomal triglyceride transfer protein in ob/ob mice.Altered hepatic triglyceride content after partial hepatectomy without impaired liver regeneration in multiple murine genetic models.FoxO1 integrates insulin signaling to VLDL production.Momordica charantia (bitter melon) reduces plasma apolipoprotein B-100 and increases hepatic insulin receptor substrate and phosphoinositide-3 kinase interactions.IRE1beta inhibits chylomicron production by selectively degrading MTP mRNA.Coordinate transcriptional repression of liver fatty acid-binding protein and microsomal triglyceride transfer protein blocks hepatic very low density lipoprotein secretion without hepatosteatosis.Pomegranate flower improves cardiac lipid metabolism in a diabetic rat model: role of lowering circulating lipids.Alcohol and lipid metabolismReduced insulin-mediated inhibition of VLDL secretion upon pharmacological activation of the liver X receptor in miceUpregulation of hepatic VLDLR via PPARα is required for the triglyceride-lowering effect of fenofibrateΩ-3 fatty acids prevent hepatic steatosis, independent of PPAR-α activity, in a murine model of parenteral nutrition-associated liver disease.Fenofibrate increases very low density lipoprotein triglyceride production despite reducing plasma triglyceride levels in APOE*3-Leiden.CETP mice.Peroxisome proliferator-activated receptor alpha target genes.HIV-1 viral protein R (Vpr) induces fatty liver in mice via LXRα and PPARα dysregulation: implications for HIV-specific pathogenesis of NAFLD.Regulation of microsomal triglyceride transfer protein.Peroxisome proliferator activated receptors and lipoprotein metabolism.PPARalpha activation increases triglyceride mass and adipose differentiation-related protein in hepatocytes.High fat diet-induced oxidative stress blocks hepatocyte nuclear factor 4α and leads to hepatic steatosis in mice.The acyl-CoA thioesterase I is regulated by PPARalpha and HNF4alpha via a distal response element in the promoter.Expression of mRNA of apolipoprotein E, apolipoprotein A-IV, and matricellular proteins in the myocardium and intensity of fibroplastic processes during experimental hypercholesterolemia.
P2860
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P2860
Activation of peroxisome proliferator-activated receptor alpha increases the expression and activity of microsomal triglyceride transfer protein in the liver
description
2005 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի հունվարին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
artículu científicu espublizáu en 2005
@ast
im Januar 2005 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2005/01/14)
@sk
vědecký článek publikovaný v roce 2005
@cs
wetenschappelijk artikel (gepubliceerd op 2005/01/14)
@nl
наукова стаття, опублікована в січні 2005
@uk
name
Activation of peroxisome proli ...... transfer protein in the liver
@ast
Activation of peroxisome proli ...... transfer protein in the liver
@en
Activation of peroxisome proli ...... transfer protein in the liver
@nl
type
label
Activation of peroxisome proli ...... transfer protein in the liver
@ast
Activation of peroxisome proli ...... transfer protein in the liver
@en
Activation of peroxisome proli ...... transfer protein in the liver
@nl
prefLabel
Activation of peroxisome proli ...... transfer protein in the liver
@ast
Activation of peroxisome proli ...... transfer protein in the liver
@en
Activation of peroxisome proli ...... transfer protein in the liver
@nl
P2093
P2860
P356
P1476
Activation of peroxisome proli ...... transfer protein in the liver
@en
P2093
Anna Ljungberg
Anna Tuneld
Caroline Améen
Daniel Lindén
Jan Oscarsson
Lennart Asp
Peter Akerblad
Ulrika Edvardsson
P2860
P304
P356
10.1074/JBC.M412107200
P407
P577
2005-01-14T00:00:00Z