Hedgehog signaling regulation of insulin production by pancreatic beta-cells
about
Deciphering the role of hedgehog signaling in pancreatic cancerHedgehog Signaling in Pancreatic Fibrosis and CancerThe thyroid hormone-inactivating type III deiodinase is expressed in mouse and human beta-cells and its targeted inactivation impairs insulin secretionDevelopment of diabetes mellitus in aging transgenic mice following suppression of pancreatic homeoprotein IDX-1Hedgehog signaling in pancreas epithelium regulates embryonic organ formation and adult beta-cell functionA feat of metabolic proportions: Pdx1 orchestrates islet development and function in the maintenance of glucose homeostasis.Menin epigenetically represses Hedgehog signaling in MEN1 tumor syndrome.Abnormal glucose homeostasis and pancreatic islet function in mice with inactivation of the Fem1b gene.Gli1 promotes cell survival and is predictive of a poor outcome in ERalpha-negative breast cancer.Primary cilia regulate Gli/Hedgehog activation in pancreasDelta-cell-specific expression of hedgehog pathway Ptch1 receptor in murine and human endocrine pancreas.Frequent deregulations in the hedgehog signaling network and cross-talks with the epidermal growth factor receptor pathway involved in cancer progression and targeted therapies.Widespread evidence of viral miRNAs targeting host pathwaysComplex disease interventions from a network model for type 2 diabetesCarriers of loss-of-function mutations in EXT display impaired pancreatic beta-cell reserve due to smaller pancreas volumeHedgehog signaling stimulates the conversion of cholesterol to steroids.Elevated Hedgehog/Gli signaling causes beta-cell dedifferentiation in mice.Two distinct sites in sonic Hedgehog combine for heparan sulfate interactions and cell signaling functions.Dynamics of embryonic pancreas development using real-time imagingRegulation of Dense-Core Granule Replenishment by Autocrine BMP Signalling in Drosophila Secondary CellsHedgehog signaling in development and homeostasis of the gastrointestinal tract.The adventures of Sonic Hedgehog in development and repair. I. Hedgehog signaling in gastrointestinal development and disease.Genetic and Molecular Basis of QTL of Diabetes in Mouse: Genes and PolymorphismsGli-similar proteins: their mechanisms of action, physiological functions, and roles in disease.VHL-mediated disruption of Sox9 activity compromises β-cell identity and results in diabetes mellitus.Hedgehog signaling and gastrointestinal cancerSonic hedgehog expression in a rat model of chronic pancreatitis.Learning from Jekyll to control Hyde: Hedgehog signaling in development and cancer.Novel molecular targets for the treatment of gastroenteropancreatic endocrine tumors: answers and unsolved problemsCanonical and non-canonical Hedgehog signalling and the control of metabolism.Exosome-like vesicles released from lipid-induced insulin-resistant muscles modulate gene expression and proliferation of beta recipient cells in mice.SHP (small heterodimer partner) suppresses the transcriptional activity and nuclear localization of Hedgehog signalling protein Gli1.Menin directly represses Gli1 expression independent of canonical Hedgehog signaling.SHh-Gli1 signaling pathway promotes cell survival by mediating baculoviral IAP repeat-containing 3 (BIRC3) gene in pancreatic cancer cells.Sonic hedgehog.Identification of genes contributing to the obese yellow Avy phenotype: caloric restriction, genotype, diet x genotype interactions.Hedgehog signals inhibit postnatal beta cell neogenesis from adult rat exocrine pancreas in vitro.Pathways governing development of stem cell-derived pancreatic β cells: lessons from embryogenesis.Sex- and Dose-Specific Effects of Maternal Bisphenol A Exposure on Pancreatic Islets of First- and Second-Generation Adult Mice Offspring.The role of adherens junction proteins in the regulation of insulin secretion.
P2860
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P2860
Hedgehog signaling regulation of insulin production by pancreatic beta-cells
description
2000 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2000
@ast
im Dezember 2000 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2000/12/01)
@sk
vědecký článek publikovaný v roce 2000
@cs
wetenschappelijk artikel (gepubliceerd op 2000/12/01)
@nl
наукова стаття, опублікована в грудні 2000
@uk
مقالة علمية (نشرت في ديسمبر 2000)
@ar
name
Hedgehog signaling regulation of insulin production by pancreatic beta-cells
@ast
Hedgehog signaling regulation of insulin production by pancreatic beta-cells
@en
Hedgehog signaling regulation of insulin production by pancreatic beta-cells
@nl
type
label
Hedgehog signaling regulation of insulin production by pancreatic beta-cells
@ast
Hedgehog signaling regulation of insulin production by pancreatic beta-cells
@en
Hedgehog signaling regulation of insulin production by pancreatic beta-cells
@nl
prefLabel
Hedgehog signaling regulation of insulin production by pancreatic beta-cells
@ast
Hedgehog signaling regulation of insulin production by pancreatic beta-cells
@en
Hedgehog signaling regulation of insulin production by pancreatic beta-cells
@nl
P2093
P3181
P1433
P1476
Hedgehog signaling regulation of insulin production by pancreatic beta-cells
@en
P2093
J. F. Habener
M. K. Thomas
N. Rastalsky
P304
P3181
P356
10.2337/DIABETES.49.12.2039
P407
P577
2000-12-01T00:00:00Z