Conformational flexibility of metazoan fatty acid synthase enables catalysis
about
Direct structural insight into the substrate-shuttling mechanism of yeast fatty acid synthase by electron cryomicroscopySubunit architecture of general transcription factor TFIIHThe dynamic organization of fungal acetyl-CoA carboxylase.Architecture of the Mediator head moduleBiochemical and Structural Study of the Atypical Acyltransferase Domain from the Mycobacterial Polyketide Synthase Pks13Structural interconversions modulate activity of Escherichia coli ribonucleotide reductaseThe Missing Linker: A Dimerization Motif Located within Polyketide Synthase ModulesInteraction of the Mediator Head Module with RNA Polymerase IITangled up in knots: structures of inactivated forms of E. coli class Ia ribonucleotide reductaseMycocerosic acid synthase exemplifies the architecture of reducing polyketide synthasesArchitecture of the polyketide synthase module: surprises from electron cryo-microscopyA conserved Mediator-CDK8 kinase module association regulates Mediator-RNA polymerase II interaction.Pick-up, transport and release of a molecular cargo using a small-molecule robotic armMaskiton: Interactive, web-based classification of single-particle electron microscopy images.Redefining the modular organization of the core Mediator complexSingle particle tomography in EMAN2Reconstruction of 3D structures of MET antibodies from electron microscopy 2D class averagesThe LINKS motif zippers trans-acyltransferase polyketide synthase assembly lines into a biosynthetic megacomplex.Single-particle EM reveals extensive conformational variability of the Ltn1 E3 ligase.Structural analysis of protein-protein interactions in type I polyketide synthasesSingle-Particle Refinement and Variability Analysis in EMAN2.1.Structural insights into nonribosomal peptide enzymatic assembly linesOptimod--an automated approach for constructing and optimizing initial models for single-particle electron microscopy.Exploring conformational modes of macromolecular assemblies by multiparticle cryo-EM.Current understanding of fatty acid biosynthesis and the acyl carrier protein.Structure and function of eukaryotic fatty acid synthases.The structures of type I polyketide synthases.The structural role of the carrier protein--active controller or passive carrier.Uncovering the structures of modular polyketide synthases.Spatial Organization of Metabolic Enzyme Complexes in Cells.Crystallization and X-ray diffraction studies of a complete bacterial fatty-acid synthase type IA TFIIH-associated mediator head is a basal factor of small nuclear spliced leader RNA gene transcription in early-diverged trypanosomes.TFIID: a closer look highlights its complexity.The changing patterns of covalent active site occupancy during catalysis on a modular polyketide synthase multienzyme revealed by ion-trap mass spectrometry.Engineering of Saccharomyces cerevisiae for the synthesis of short chain fatty acids.Stereodivergent synthesis with a programmable molecular machine.X-rays in the Cryo-Electron Microscopy Era: Structural Biology's Dynamic Future.Directed accumulation of less toxic pimaricin derivatives by improving the efficiency of a polyketide synthase dehydratase domain.Protein dynamic communities from elastic network models align closely to the communities defined by molecular dynamics.
P2860
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P2860
Conformational flexibility of metazoan fatty acid synthase enables catalysis
description
2009 nî lūn-bûn
@nan
2009 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Conformational flexibility of metazoan fatty acid synthase enables catalysis
@ast
Conformational flexibility of metazoan fatty acid synthase enables catalysis
@en
Conformational flexibility of metazoan fatty acid synthase enables catalysis
@nl
type
label
Conformational flexibility of metazoan fatty acid synthase enables catalysis
@ast
Conformational flexibility of metazoan fatty acid synthase enables catalysis
@en
Conformational flexibility of metazoan fatty acid synthase enables catalysis
@nl
prefLabel
Conformational flexibility of metazoan fatty acid synthase enables catalysis
@ast
Conformational flexibility of metazoan fatty acid synthase enables catalysis
@en
Conformational flexibility of metazoan fatty acid synthase enables catalysis
@nl
P2093
P2860
P3181
P356
P1476
Conformational flexibility of metazoan fatty acid synthase enables catalysis
@en
P2093
Edward J Brignole
Francisco J Asturias
Stuart Smith
P2860
P2888
P304
P3181
P356
10.1038/NSMB.1532
P577
2009-01-18T00:00:00Z