VLA-4 integrin concentrates at the peripheral supramolecular activation complex of the immune synapse and drives T helper 1 responses
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Function and Dynamics of Tetraspanins during Antigen Recognition and Immunological Synapse FormationDiacylglycerol Kinases: Shaping Diacylglycerol and Phosphatidic Acid Gradients to Control Cell PolarityPolymorphisms in the α4 integrin of neotropical primates: insights for binding of natural ligands and HIV-1 gp120 to the human α4β7Natalizumab exerts direct signaling capacity and supports a pro-inflammatory phenotype in some patients with multiple sclerosisThe interaction affinity between vascular cell adhesion molecule-1 (VCAM-1) and very late antigen-4 (VLA-4) analyzed by quantitative FRETThe N terminus of SKAP55 enables T cell adhesion to TCR and integrin ligands via distinct mechanisms.B-cell activation by membrane-bound antigens is facilitated by the interaction of VLA-4 with VCAM-1Beta1 integrins differentially control extravasation of inflammatory cell subsets into the CNS during autoimmunityThe mitochondrial fission factor dynamin-related protein 1 modulates T-cell receptor signalling at the immune synapse.Therapeutic effect of all-trans-retinoic acid (at-RA) on an autoimmune nephritis experimental model: role of the VLA-4 integrin.VCAM-1 and VLA-4 modulate dendritic cell IL-12p40 production in experimental visceral leishmaniasis.Effects of natalizumab treatment on Foxp3+ T regulatory cells.Control of alpha4beta7 integrin expression and CD4 T cell homing by the beta1 integrin subunit.Integrated genomic and prospective clinical studies show the importance of modular pleiotropy for disease susceptibility, diagnosis and treatment.T-cell receptor signaling to integrins.Integrin alpha L controls the homing of regulatory T cells during CNS autoimmunity in the absence of integrin alpha 4.Natalizumab restores aberrant miRNA expression profile in multiple sclerosis and reveals a critical role for miR-20b.Increased B cell and cytotoxic NK cell proportions and increased T cell responsiveness in blood of natalizumab-treated multiple sclerosis patients.Ectopic expression of vascular cell adhesion molecule-1 as a new mechanism for tumor immune evasion.Cutting edge: loss of α4 integrin expression differentially affects the homing of Th1 and Th17 cellsTh17 lymphocytes traffic to the central nervous system independently of α4 integrin expression during EAESodium benzoate, a food additive and a metabolite of cinnamon, modifies T cells at multiple steps and inhibits adoptive transfer of experimental allergic encephalomyelitisTherapeutic anti-integrin (alpha4 and alphaL) monoclonal antibodies: two-edged swords?Natalizumab and progressive multifocal leukoencephalopathy: migrating towards safe adhesion molecule therapy in multiple sclerosis.Integrin antagonists as therapeutics for inflammatory diseases.Postthymic expansion in human CD4 naive T cells defined by expression of functional high-affinity IL-2 receptorsFunctional insights on the polarized redistribution of leukocyte integrins and their ligands during leukocyte migration and immune interactions.The WAVE2 complex regulates T cell receptor signaling to integrins via Abl- and CrkL-C3G-mediated activation of Rap1.Adhesions ring: a structural comparison between podosomes and the immune synapse.Leukocyte integrins and their ligand interactions.Integrin function in T-cell homing to lymphoid and nonlymphoid sites: getting there and staying there.CD11c⁺ cells primed with unrelated antigens facilitate an accelerated immune response to influenza virus in mice.Role of beta7 integrins in intestinal lymphocyte homing and retention.Integrin modulators: a patent review.Location, location, location: the impact of migratory heterogeneity on T cell function.Integrating receptor signal inputs that influence small Rho GTPase activation dynamics at the immunological synapseRole of Drebrin at the Immunological Synapse.WAVE2 regulates high-affinity integrin binding by recruiting vinculin and talin to the immunological synapse.Cytomegalovirus-Associated CD4(+) CD28(null) Cells in NKG2D-Dependent Glomerular Endothelial Injury and Kidney Allograft Dysfunction.Expression of VLA-4 molecule in PBMC from patients with hemorrhagic fever with renal syndrome.
P2860
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P2860
VLA-4 integrin concentrates at the peripheral supramolecular activation complex of the immune synapse and drives T helper 1 responses
description
2004 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
article publié dans les Procee ...... f the United States of America
@fr
artículu científicu espublizáu en 2004
@ast
im Juli 2004 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2004/07/27)
@sk
vědecký článek publikovaný v roce 2004
@cs
wetenschappelijk artikel (gepubliceerd op 2004/07/27)
@nl
наукова стаття, опублікована в липні 2004
@uk
name
VLA-4 integrin concentrates at ...... nd drives T helper 1 responses
@ast
VLA-4 integrin concentrates at ...... nd drives T helper 1 responses
@en
VLA-4 integrin concentrates at ...... nd drives T helper 1 responses
@nl
type
label
VLA-4 integrin concentrates at ...... nd drives T helper 1 responses
@ast
VLA-4 integrin concentrates at ...... nd drives T helper 1 responses
@en
VLA-4 integrin concentrates at ...... nd drives T helper 1 responses
@nl
prefLabel
VLA-4 integrin concentrates at ...... nd drives T helper 1 responses
@ast
VLA-4 integrin concentrates at ...... nd drives T helper 1 responses
@en
VLA-4 integrin concentrates at ...... nd drives T helper 1 responses
@nl
P2093
P2860
P50
P356
P1476
VLA-4 integrin concentrates at ...... nd drives T helper 1 responses
@en
P2093
Ana Molina
Angeles Ursa
Ester Escudero
Francisco Mampaso
Reyes Tejedor
P2860
P304
11058-11063
P356
10.1073/PNAS.0307927101
P407
P577
2004-07-19T00:00:00Z