Palmitate induces insulin resistance in H4IIEC3 hepatocytes through reactive oxygen species produced by mitochondria
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Free fatty acid-induced PP2A hyperactivity selectively impairs hepatic insulin action on glucose metabolismBiological and Nutritional Properties of Palm Oil and Palmitic Acid: Effects on HealthSIRT3 regulates progression and development of diseases of aging.Free Fatty acids and their metabolism affect function and survival of podocytesSIRT3 as a Regulator of Non-alcoholic Fatty Liver DiseaseMitochondrial morphology in metabolic diseasesMitochondrial dynamics in diabetic cardiomyopathyActivation of the Liver X Receptor by Agonist TO901317 Improves Hepatic Insulin Resistance via Suppressing Reactive Oxygen Species and JNK PathwayLipotoxicity in the liver.Transgenic control of mitochondrial fission induces mitochondrial uncoupling and relieves diabetic oxidative stress.Insulin resistance in non-obese subjects is associated with activation of the JNK pathway and impaired insulin signaling in skeletal muscle.Saikosaponins induced hepatotoxicity in mice via lipid metabolism dysregulation and oxidative stress: a proteomic studyDisruption of inducible 6-phosphofructo-2-kinase ameliorates diet-induced adiposity but exacerbates systemic insulin resistance and adipose tissue inflammatory response.Genetic ablation of calcium-independent phospholipase A2gamma prevents obesity and insulin resistance during high fat feeding by mitochondrial uncoupling and increased adipocyte fatty acid oxidation.PPAR/RXR Regulation of Fatty Acid Metabolism and Fatty Acid omega-Hydroxylase (CYP4) Isozymes: Implications for Prevention of Lipotoxicity in Fatty Liver DiseaseEvolving concepts in the pathogenesis of NASH: beyond steatosis and inflammation.Redox control of liver function in health and diseaseFFA-induced hepatic insulin resistance in vivo is mediated by PKCδ, NADPH oxidase, and oxidative stress.Hypoxia, lipids, and cancer: surviving the harsh tumor microenvironmentConcentration-dependent dual effects of hydrogen peroxide on insulin signal transduction in H4IIEC hepatocytes.The effects of palmitate on hepatic insulin resistance are mediated by NADPH Oxidase 3-derived reactive oxygen species through JNK and p38MAPK pathwaysDecreasing mitochondrial fission alleviates hepatic steatosis in a murine model of nonalcoholic fatty liver diseasePalmitoleate induces hepatic steatosis but suppresses liver inflammatory response in mice.Nonalcoholic Fatty liver disease: pathogenesis and therapeutics from a mitochondria-centric perspective.Different effects of oleate vs. palmitate on mitochondrial function, apoptosis, and insulin signaling in L6 skeletal muscle cells: role of oxidative stressSteatosis inhibits liver cell store-operated Ca²⁺ entry and reduces ER Ca²⁺ through a protein kinase C-dependent mechanism.Supplementation of persimmon leaf ameliorates hyperglycemia, dyslipidemia and hepatic fat accumulation in type 2 diabetic mice.Mitochondrial DNA damage and dysfunction, and oxidative stress are associated with endoplasmic reticulum stress, protein degradation and apoptosis in high fat diet-induced insulin resistance mice.Carboxylesterase 1 gene duplication and mRNA expression in adipose tissue are linked to obesity and metabolic functionMitochondrial dysfunction and insulin resistance: an update.Lysophosphatidylcholine as an effector of fatty acid-induced insulin resistance.Metabolic regulation by C1q/TNF-related protein-13 (CTRP13): activation OF AMP-activated protein kinase and suppression of fatty acid-induced JNK signalingMetformin ameliorates hepatic steatosis and inflammation without altering adipose phenotype in diet-induced obesity.The metabolically benign and malignant fatty liver.Ectopic fat accumulation and distant organ-specific insulin resistance in Japanese people with nonalcoholic fatty liver disease.Influence of dietary saturated fat intake on endothelial fibrinolytic capacity in adults.Liver steatosis is associated with insulin resistance in skeletal muscle rather than in the liver in Japanese patients with non-alcoholic fatty liver disease.Increased expression of zinc finger protein 267 in non-alcoholic fatty liver disease.Neuroendocrine and metabolic components of dopamine agonist amelioration of metabolic syndrome in SHR ratsProtection from palmitate-induced mitochondrial DNA damage prevents from mitochondrial oxidative stress, mitochondrial dysfunction, apoptosis, and impaired insulin signaling in rat L6 skeletal muscle cells.
P2860
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P2860
Palmitate induces insulin resistance in H4IIEC3 hepatocytes through reactive oxygen species produced by mitochondria
description
2009 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի մայիսին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
artículu científicu espublizáu en 2009
@ast
im Mai 2009 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2009/05/29)
@sk
vědecký článek publikovaný v roce 2009
@cs
wetenschappelijk artikel (gepubliceerd op 2009/05/29)
@nl
наукова стаття, опублікована в травні 2009
@uk
name
Palmitate induces insulin resi ...... ecies produced by mitochondria
@ast
Palmitate induces insulin resi ...... ecies produced by mitochondria
@en
Palmitate induces insulin resi ...... ecies produced by mitochondria
@nl
type
label
Palmitate induces insulin resi ...... ecies produced by mitochondria
@ast
Palmitate induces insulin resi ...... ecies produced by mitochondria
@en
Palmitate induces insulin resi ...... ecies produced by mitochondria
@nl
prefLabel
Palmitate induces insulin resi ...... ecies produced by mitochondria
@ast
Palmitate induces insulin resi ...... ecies produced by mitochondria
@en
Palmitate induces insulin resi ...... ecies produced by mitochondria
@nl
P2093
P2860
P3181
P356
P1476
Palmitate induces insulin resi ...... ecies produced by mitochondria
@en
P2093
Hiroaki Takayama
Hirofumi Misu
Hiroyo Noda
Hitoshi Ando
Ken-Ichi Miyamoto
Naoto Matsuzawa-Nagata
Satoko Nabemoto
Seiichiro Kurita
Seiji Nakamura
Shuichi Kaneko
P2860
P304
14809–14818
P3181
P356
10.1074/JBC.M901488200
P407
P577
2009-05-29T00:00:00Z