N-acetylcysteine attenuates PKCbeta2 overexpression and myocardial hypertrophy in streptozotocin-induced diabetic rats
about
Contractile apparatus dysfunction early in the pathophysiology of diabetic cardiomyopathyN-acetylcysteine and allopurinol synergistically enhance cardiac adiponectin content and reduce myocardial reperfusion injury in diabetic ratsHyperglycemic and hyperlipidemic conditions alter cardiac cell biomechanical propertiesDeficiency of a lipid droplet protein, perilipin 5, suppresses myocardial lipid accumulation, thereby preventing type 1 diabetes-induced heart malfunctionExperimental therapies in hypertrophic cardiomyopathyLow molecular weight fucoidan alleviates cardiac dysfunction in diabetic Goto-Kakizaki rats by reducing oxidative stress and cardiomyocyte apoptosis.An altered pattern of myocardial histopathological and molecular changes underlies the different characteristics of type-1 and type-2 diabetic cardiac dysfunctionRegulation of Inducible Nitric Oxide Synthase (iNOS) and its Potential Role in Insulin Resistance, Diabetes and Heart FailureEffects of N-acetylcysteine on nicotinamide dinucleotide phosphate oxidase activation and antioxidant status in heart, lung, liver and kidney in streptozotocin-induced diabetic rats.N-Acetyl Cysteine Inhibits Endothelin-1-Induced ROS Dependent Cardiac Hypertrophy through Superoxide Dismutase RegulationRhoA/rock signaling mediates peroxynitrite-induced functional impairment of Rat coronary vesselsDiabetes-induced increased oxidative stress in cardiomyocytes is sustained by a positive feedback loop involving Rho kinase and PKCβ2.Exercise-induced cardiac performance in autoimmune (type 1) diabetes is associated with a decrease in myocardial diacylglycerol.Hyperglycemia-induced protein kinase C β2 activation induces diastolic cardiac dysfunction in diabetic rats by impairing caveolin-3 expression and Akt/eNOS signaling.Cypermethrin Induces Macrophages Death through Cell Cycle Arrest and Oxidative Stress-Mediated JNK/ERK Signaling Regulated ApoptosisSuperoxide and respiratory coupling in mitochondria of insulin-deficient diabetic ratsHyperinsulinemia and sulfonylurea use are independently associated with left ventricular diastolic dysfunction in patients with type 2 diabetes mellitus with suboptimal blood glucose controlHyperglycemia-induced inhibition of DJ-1 expression compromised the effectiveness of ischemic postconditioning cardioprotection in rats.N-Acetylcysteine Attenuates Diabetic Myocardial Ischemia Reperfusion Injury through Inhibiting Excessive Autophagy.Reducing methylglyoxal as a therapeutic target for diabetic heart disease.Damaging effects of hyperglycemia on cardiovascular function: spotlight on glucose metabolic pathways.Role of protein kinase C beta2 activation in TNF-alpha-induced human vascular endothelial cell apoptosis.Selective inhibition of protein kinase C beta(2) attenuates inducible nitric oxide synthase-mediated cardiovascular abnormalities in streptozotocin-induced diabetic rats.Antioxidant N-acetylcysteine attenuates the reduction of Brg1 protein expression in the myocardium of type 1 diabetic rats.Inhibition of aldehyde dehydrogenase 2 by oxidative stress is associated with cardiac dysfunction in diabetic rats.Oxidative stress is not associated with vascular dysfunction in a model of alloxan-induced diabetic rats.Myocyte membrane and microdomain modifications in diabetes: determinants of ischemic tolerance and cardioprotection.Ethanol-mediated expression of connective tissue growth factor (CCN2) in mouse pancreatic stellate cells.Mechanism of myocardial ischemia/reperfusion-induced acute kidney injury through DJ-1/Nrf2 pathway in diabetic rats.Synergy of isoflurane preconditioning and propofol postconditioning reduces myocardial reperfusion injury in patients.FP-receptor gene silencing ameliorates myocardial fibrosis and protects from diabetic cardiomyopathy.PKCβ inhibition with ruboxistaurin reduces oxidative stress and attenuates left ventricular hypertrophy and dysfunction in rats with streptozotocin-induced diabetes.Protective effect of ginsenoside Rb1 against myocardial ischemia/reperfusion injury in streptozotocin-induced diabetic rats.Palmitic acid, but not high-glucose, induced myocardial apoptosis is alleviated by N‑acetylcysteine due to attenuated mitochondrial-derived ROS accumulation-induced endoplasmic reticulum stress.Diabetic cardiomyopathy
P2860
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P2860
N-acetylcysteine attenuates PKCbeta2 overexpression and myocardial hypertrophy in streptozotocin-induced diabetic rats
description
2007 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի մարտին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2007
@ast
im März 2007 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2007/03/01)
@sk
vědecký článek publikovaný v roce 2007
@cs
wetenschappelijk artikel (gepubliceerd op 2007/03/01)
@nl
наукова стаття, опублікована в березні 2007
@uk
مقالة علمية (نشرت في مارس 2007)
@ar
name
N-acetylcysteine attenuates PK ...... ozotocin-induced diabetic rats
@ast
N-acetylcysteine attenuates PK ...... ozotocin-induced diabetic rats
@en
N-acetylcysteine attenuates PK ...... ozotocin-induced diabetic rats
@nl
type
label
N-acetylcysteine attenuates PK ...... ozotocin-induced diabetic rats
@ast
N-acetylcysteine attenuates PK ...... ozotocin-induced diabetic rats
@en
N-acetylcysteine attenuates PK ...... ozotocin-induced diabetic rats
@nl
prefLabel
N-acetylcysteine attenuates PK ...... ozotocin-induced diabetic rats
@ast
N-acetylcysteine attenuates PK ...... ozotocin-induced diabetic rats
@en
N-acetylcysteine attenuates PK ...... ozotocin-induced diabetic rats
@nl
P2093
P2860
P3181
P1476
N-acetylcysteine attenuates PK ...... ozotocin-induced diabetic rats
@en
P2093
Jihong Jiang
John H McNeill
Kuo-Hsing Kuo
Tianhai Guo
Zhengyuan Xia
Zhixin Guo
P2860
P304
P3181
P356
10.1016/J.CARDIORES.2006.11.033
P577
2006-11-30T00:00:00Z