NMDA receptor activation mediates copper homeostasis in hippocampal neurons
about
A single PDZ domain protein interacts with the Menkes copper ATPase, ATP7A. A new protein implicated in copper homeostasisBiochemical basis of regulation of human copper-transporting ATPasesNeonatal diagnosis and treatment of Menkes diseaseMissense mutations in the copper transporter gene ATP7A cause X-linked distal hereditary motor neuropathyCellular multitasking: the dual role of human Cu-ATPases in cofactor delivery and intracellular copper balanceZinc and copper modulate Alzheimer Abeta levels in human cerebrospinal fluidMulti-Target Directed Donepezil-Like Ligands for Alzheimer's DiseaseCopper signaling in the mammalian nervous system: synaptic effectsSynthetic fluorescent probes for studying copper in biological systemsATP7A-related copper transport diseases-emerging concepts and future trendsConditional knockout of the Menkes disease copper transporter demonstrates its critical role in embryogenesisRole of the Menkes copper-transporting ATPase in NMDA receptor-mediated neuronal toxicityNumerical Simulations Reveal Randomness of Cu(II) Induced Aβ Peptide Dimerization under Conditions Present in Glutamatergic SynapsesIn vivo and in vitro analyses of amygdalar function reveal a role for copperEssential roles in development and pigmentation for the Drosophila copper transporter DmATP7.Binding of zinc(II) and copper(II) to the full-length Alzheimer's amyloid-beta peptide.Cerebral bioimaging of Cu, Fe, Zn, and Mn in the MPTP mouse model of Parkinson's disease using laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS).Copper: from neurotransmission to neuroproteostasisMetal imaging in neurodegenerative diseases.Copper and angiogenesis: unravelling a relationship key to cancer progression.Copper is an endogenous modulator of neural circuit spontaneous activity.Presenilins promote the cellular uptake of copper and zinc and maintain copper chaperone of SOD1-dependent copper/zinc superoxide dismutase activity.Alzheimer's disease and metals: a review of the involvement of cellular membrane receptors in metallosignalling.Calcium-dependent copper redistributions in neuronal cells revealed by a fluorescent copper sensor and X-ray fluorescence microscopy.Favorably skewed X-inactivation accounts for neurological sparing in female carriers of Menkes disease.Molecular correlates of epilepsy in early diagnosed and treated Menkes diseaseGlutamate-mediated primary somatosensory cortex excitability correlated with circulating copper and ceruloplasminX-linked spinal muscular atrophy in mice caused by autonomous loss of ATP7A in the motor neuronATP7A gene addition to the choroid plexus results in long-term rescue of the lethal copper transport defect in a Menkes disease mouse modelATP7A (Menkes protein) functions in axonal targeting and synaptogenesis.Altered intracellular localization and valosin-containing protein (p97 VCP) interaction underlie ATP7A-related distal motor neuropathyBone marrow from blotchy mice is dispensable to regulate blood copper and aortic pathologies but required for inflammatory mediator production in LDLR-deficient mice during chronic angiotensin II infusionAltered ATP7A expression and other compensatory responses in a murine model of Menkes disease.Cellular sensing and transport of metal ions: implications in micronutrient homeostasis.Autonomous requirements of the Menkes disease protein in the nervous system.Links between copper and cholesterol in Alzheimer's disease.The modulation of metal bio-availability as a therapeutic strategy for the treatment of Alzheimer's disease.Role of the P-Type ATPases, ATP7A and ATP7B in brain copper homeostasis.Clinical outcomes in Menkes disease patients with a copper-responsive ATP7A mutation, G727R.Reversal of physiological deficits caused by diminished levels of peptidylglycine alpha-amidating monooxygenase by dietary copper
P2860
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P2860
NMDA receptor activation mediates copper homeostasis in hippocampal neurons
description
2005 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի հունվարին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2005
@ast
im Januar 2005 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2005/01/05)
@sk
vědecký článek publikovaný v roce 2005
@cs
wetenschappelijk artikel (gepubliceerd op 2005/01/05)
@nl
наукова стаття, опублікована в січні 2005
@uk
مقالة علمية (نشرت في 5-1-2005)
@ar
name
NMDA receptor activation mediates copper homeostasis in hippocampal neurons
@ast
NMDA receptor activation mediates copper homeostasis in hippocampal neurons
@en
NMDA receptor activation mediates copper homeostasis in hippocampal neurons
@nl
type
label
NMDA receptor activation mediates copper homeostasis in hippocampal neurons
@ast
NMDA receptor activation mediates copper homeostasis in hippocampal neurons
@en
NMDA receptor activation mediates copper homeostasis in hippocampal neurons
@nl
prefLabel
NMDA receptor activation mediates copper homeostasis in hippocampal neurons
@ast
NMDA receptor activation mediates copper homeostasis in hippocampal neurons
@en
NMDA receptor activation mediates copper homeostasis in hippocampal neurons
@nl
P2093
P3181
P1476
NMDA receptor activation mediates copper homeostasis in hippocampal neurons
@en
P2093
Ann Marie Craig
Jonathan D Gitlin
Michelle L Schlief
P304
P3181
P356
10.1523/JNEUROSCI.3699-04.2005
P407
P577
2005-01-05T00:00:00Z