Oxidative stress activates the c-Abl/p73 proapoptotic pathway in Niemann-Pick type C neurons
about
Disruption in connexin-based communication is associated with intracellular Ca²⁺ signal alterations in astrocytes from Niemann-Pick type C micePre-symptomatic activation of antioxidant responses and alterations in glucose and pyruvate metabolism in Niemann-Pick Type C1-deficient murine brainMechanisms of activation of the transcription factor Nrf2 by redox stressors, nutrient cues, and energy status and the pathways through which it attenuates degenerative diseaseAlteration of gene expression profile in Niemann-Pick type C mice correlates with tissue damage and oxidative stressc-Abl mediates angiotensin II-induced apoptosis in podocytesAdaptations of energy metabolism associated with increased levels of mitochondrial cholesterol in Niemann-Pick type C1-deficient cells.Reactive oxygen species trigger motoneuron death in non-cell-autonomous models of ALS through activation of c-Abl signalingOxidative stress: a pathogenic mechanism for Niemann-Pick type C disease.Quantitative Proteomics of Human Fibroblasts with I1061T Mutation in Niemann-Pick C1 (NPC1) Protein Provides Insights into the Disease Pathogenesis.Microarray expression analysis and identification of serum biomarkers for Niemann-Pick disease, type C1.Quantitative proteomic analysis of Niemann-Pick disease, type C1 cerebellum identifies protein biomarkers and provides pathological insight.Efficacy of N-acetylcysteine in phenotypic suppression of mouse models of Niemann-Pick disease, type C1.Neuronal gene repression in Niemann-Pick type C models is mediated by the c-Abl/HDAC2 signaling pathway.Human and mouse neuroinflammation markers in Niemann-Pick disease, type C1.Sphingolipids and mitochondrial function, lessons learned from yeastThe emerging role of matrix metalloproteases of the ADAM family in male germ cell apoptosis.Oxidative Stress, DNA Damage, and c-Abl Signaling: At the Crossroad in Neurodegenerative Diseases?Sphingolipids and mitochondrial function in budding yeast.Vitamin E dietary supplementation improves neurological symptoms and decreases c-Abl/p73 activation in Niemann-Pick C miceNiemann-Pick type C1 patient-specific induced pluripotent stem cells display disease specific hallmarksGeneration of a human neuronal stable cell model for niemann-pick C disease by RNA interference.7b, a novel amonafide analog, inhibited proliferation and phorbol 12-myristate 13-acetate/phytohemagglutinin-induced inflammatory responses of Jurkat T cells via p73-dependent pathway and decrease of nuclear factor-κB DNA-binding, respectively.Increased copper levels in in vitro and in vivo models of Niemann-Pick C disease.Role of Diffusion Tensor Imaging in Prognostication and Treatment Monitoring in Niemann-Pick Disease Type C1.The Roles of P53 and its Family Proteins, P63 and P73, in the DNA Damage Stress Response in Organogenesis Stage Mouse Embryos.
P2860
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P2860
Oxidative stress activates the c-Abl/p73 proapoptotic pathway in Niemann-Pick type C neurons
description
2011 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հունվարին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2011
@ast
im Jahr 2011 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2011/01/01)
@sk
vědecký článek publikovaný v roce 2011
@cs
wetenschappelijk artikel (gepubliceerd op 2011/01/01)
@nl
наукова стаття, опублікована в січні 2011
@uk
مقالة علمية (نشرت عام 2011)
@ar
name
Oxidative stress activates the ...... in Niemann-Pick type C neurons
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Oxidative stress activates the ...... in Niemann-Pick type C neurons
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Oxidative stress activates the ...... in Niemann-Pick type C neurons
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type
label
Oxidative stress activates the ...... in Niemann-Pick type C neurons
@ast
Oxidative stress activates the ...... in Niemann-Pick type C neurons
@en
Oxidative stress activates the ...... in Niemann-Pick type C neurons
@nl
prefLabel
Oxidative stress activates the ...... in Niemann-Pick type C neurons
@ast
Oxidative stress activates the ...... in Niemann-Pick type C neurons
@en
Oxidative stress activates the ...... in Niemann-Pick type C neurons
@nl
P2093
P1476
Oxidative stress activates the ...... in Niemann-Pick type C neurons
@en
P2093
Alejandra R. Alvarez
Andres Klein
Carola Maldonado
Claudio Hetz
Fermín Robledo
Francisco J. Muñoz
Karen Perez de Arce
Lina M. Vargas
Marcela Gonzalez
Silvana Zanlungo
P304
P356
10.1016/J.NBD.2010.09.008
P577
2011-01-01T00:00:00Z